haloperidol has been researched along with Delayed Effects, Prenatal Exposure in 48 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gestational methylazoxymethanol acetate (MAM) treatment produces offspring with adult phenotype relevant to schizophrenia, including positive- and negative-like symptoms, cognitive deficits, dopaminergic dysfunction, structural and functional abnormalities." | 7.96 | Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment. ( Babinska, Z; Bucolo, C; D'Addario, C; Di Bartolomeo, M; Di Marco, R; Di Marzo, V; Drago, F; Drazanova, E; Fedotova, J; Giurdanella, G; Iannotti, FA; Kratka, L; Mechoulam, R; Micale, V; Pekarik, V; Piscitelli, F; Platania, CBM; Ruda-Kucerova, J; Salomone, S; Starcuk, Z; Stark, T; Sulcova, A; Wotjak, CT, 2020) |
| "Gestational methylazoxymethanol acetate (MAM) treatment produces offspring with adult phenotype relevant to schizophrenia, including positive- and negative-like symptoms, cognitive deficits, dopaminergic dysfunction, structural and functional abnormalities." | 3.96 | Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment. ( Babinska, Z; Bucolo, C; D'Addario, C; Di Bartolomeo, M; Di Marco, R; Di Marzo, V; Drago, F; Drazanova, E; Fedotova, J; Giurdanella, G; Iannotti, FA; Kratka, L; Mechoulam, R; Micale, V; Pekarik, V; Piscitelli, F; Platania, CBM; Ruda-Kucerova, J; Salomone, S; Starcuk, Z; Stark, T; Sulcova, A; Wotjak, CT, 2020) |
| "The methionine-folate cycle-dependent one-carbon metabolism is implicated in the pathophysiology of schizophrenia." | 3.88 | Prenatal one-carbon metabolism dysregulation programs schizophrenia-like deficits. ( Abbott, GW; Alachkar, A; Civelli, O; Hamzeh, AR; Lee, SM; Sanathara, N; Wang, L; Wang, Z; Xu, X; Yoshimura, R, 2018) |
| "Rodents exposed prenatally to valproic acid (VPA) exhibit autism spectrum disorder (ASD)-like behavioral abnormalities." | 3.85 | Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice. ( Ago, Y; Hara, Y; Hasebe, S; Hashimoto, H; Kawase, H; Matsuda, T; Nakazawa, T; Takuma, K; Tanabe, W; Taruta, A; Tsukada, S, 2017) |
| " More recently our laboratory has reported that prenatal exposure to haloperidol (HAL), a neuroleptic which binds to and blocks dopamine receptor sites in the adult brain, permanently stunts body and brain growth when that exposure extends throughout postimplantation pregnancy." | 3.69 | Prenatal neuroleptic exposure and growth stunting in the rat: an in vivo and in vitro examination of sensitive periods and possible mechanisms. ( Grafton, TF; Hansen, DK; Holson, RR; Webb, PJ, 1994) |
| " The dopaminergic turnover was measured by 3,4-dihyroxyphenilacetic acid content and 3H-Spiperone binding has been carried out to determine dopaminergic receptor alterations induced by chronic ethanol consumption during pregnancy." | 3.66 | Effects of ethanol, given during pregnancy, on the offspring dopaminergic system. ( Covelli, V; Lucchi, L; Petkov, VV; Spano, PF; Trabucchi, M, 1983) |
| "Schizophrenia is a severe neuropsychiatric disease associated with substantially higher mortality." | 1.62 | Interacting effects of the MAM model of schizophrenia and antipsychotic treatment: Untargeted proteomics approach in adipose tissue. ( Bienertova-Vasku, J; Horska, K; Hruska, P; Kucera, J; Kuruczova, D; Micale, V; Ruda-Kucerova, J, 2021) |
| "Haloperidol treatment during pre- and post-natal period affects maternal behavior and this may have long-term effects on the offspring." | 1.37 | The effect of haloperidol on maternal behavior in WAG/Rij rats and its consequences in the offspring. ( Dobryakova, YV; Dubynin, VA; Luijtelaar, GV, 2011) |
| "Transient prenatal Vitamin D deficiency is considered a developmental model in schizophrenia research." | 1.33 | Pharmacological treatment to augment hole board habituation in prenatal Vitamin D-deficient rats. ( Becker, A; Grecksch, G, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (33.33) | 18.7374 |
| 1990's | 11 (22.92) | 18.2507 |
| 2000's | 8 (16.67) | 29.6817 |
| 2010's | 11 (22.92) | 24.3611 |
| 2020's | 2 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Stark, T | 1 |
| Di Bartolomeo, M | 1 |
| Di Marco, R | 1 |
| Drazanova, E | 1 |
| Platania, CBM | 1 |
| Iannotti, FA | 1 |
| Ruda-Kucerova, J | 2 |
| D'Addario, C | 1 |
| Kratka, L | 1 |
| Pekarik, V | 1 |
| Piscitelli, F | 1 |
| Babinska, Z | 1 |
| Fedotova, J | 1 |
| Giurdanella, G | 1 |
| Salomone, S | 1 |
| Sulcova, A | 1 |
| Bucolo, C | 1 |
| Wotjak, CT | 1 |
| Starcuk, Z | 1 |
| Drago, F | 1 |
| Mechoulam, R | 1 |
| Di Marzo, V | 1 |
| Micale, V | 2 |
| Kucera, J | 1 |
| Horska, K | 1 |
| Hruska, P | 1 |
| Kuruczova, D | 1 |
| Bienertova-Vasku, J | 1 |
| Hara, Y | 1 |
| Ago, Y | 1 |
| Taruta, A | 1 |
| Hasebe, S | 1 |
| Kawase, H | 1 |
| Tanabe, W | 1 |
| Tsukada, S | 1 |
| Nakazawa, T | 1 |
| Hashimoto, H | 1 |
| Matsuda, T | 1 |
| Takuma, K | 1 |
| Alachkar, A | 1 |
| Wang, L | 1 |
| Yoshimura, R | 1 |
| Hamzeh, AR | 1 |
| Wang, Z | 1 |
| Sanathara, N | 1 |
| Lee, SM | 1 |
| Xu, X | 1 |
| Abbott, GW | 1 |
| Civelli, O | 1 |
| Wang, H | 1 |
| Li, JT | 1 |
| Zhang, Y | 1 |
| Liu, R | 1 |
| Wang, XD | 1 |
| Si, TM | 1 |
| Su, YA | 1 |
| Takahashi, K | 1 |
| Nakagawasai, O | 1 |
| Sakuma, W | 1 |
| Nemoto, W | 1 |
| Odaira, T | 1 |
| Lin, JR | 1 |
| Onogi, H | 1 |
| Srivastava, LK | 1 |
| Tan-No, K | 1 |
| Akar, M | 1 |
| Kasapkara, ÇS | 1 |
| Özbek, MN | 1 |
| Tüzün, H | 1 |
| Aldudak, B | 1 |
| Kanar, B | 1 |
| Lilienthal, H | 1 |
| Korkalainen, M | 1 |
| Andersson, PL | 1 |
| Viluksela, M | 1 |
| Fiore, M | 1 |
| Di Fausto, V | 1 |
| Iannitelli, A | 1 |
| Aloe, L | 1 |
| Meyer, U | 1 |
| Spoerri, E | 1 |
| Yee, BK | 1 |
| Schwarz, MJ | 1 |
| Feldon, J | 1 |
| Kirsten, TB | 1 |
| Taricano, M | 1 |
| Flório, JC | 1 |
| Palermo-Neto, J | 1 |
| Bernardi, MM | 1 |
| Soiza-Reilly, M | 1 |
| Azcurra, JM | 1 |
| Dobryakova, YV | 1 |
| Dubynin, VA | 1 |
| Luijtelaar, GV | 1 |
| Rosengarten, H | 1 |
| Quartermain, D | 1 |
| Zuckerman, L | 1 |
| Rehavi, M | 1 |
| Nachman, R | 1 |
| Weiner, I | 1 |
| Collins, KO | 1 |
| Comer, JB | 1 |
| Becker, A | 1 |
| Grecksch, G | 1 |
| Romero, E | 1 |
| Ali, C | 1 |
| Molina-Holgado, E | 1 |
| Castellano, B | 1 |
| Guaza, C | 1 |
| Borrell, J | 1 |
| Lucchi, L | 2 |
| Covelli, V | 1 |
| Petkov, VV | 1 |
| Spano, PF | 2 |
| Trabucchi, M | 2 |
| Spear, LP | 1 |
| Brake, SC | 1 |
| Feigenbaum, JJ | 1 |
| Yanai, J | 1 |
| Hull, EM | 1 |
| Nishita, JK | 1 |
| Bitran, D | 1 |
| Dalterio, S | 1 |
| Bhanot, R | 1 |
| Wilkinson, M | 1 |
| Madsen, JR | 1 |
| Campbell, A | 1 |
| Baldessarini, RJ | 1 |
| Ikeda, H | 1 |
| Henderson, MG | 1 |
| McMillen, BA | 1 |
| Holson, RR | 4 |
| Webb, PJ | 1 |
| Grafton, TF | 1 |
| Hansen, DK | 1 |
| Castro, R | 2 |
| Brito, B | 2 |
| Segovia, J | 1 |
| Martín-Trujillo, JM | 1 |
| Notario, V | 2 |
| Breum, L | 1 |
| Astrup, A | 1 |
| Quaade, F | 1 |
| Singh, Y | 2 |
| Jaiswal, AK | 3 |
| Singh, M | 3 |
| Bhattacharya, SK | 3 |
| Singh, KP | 1 |
| Mohan, MS | 1 |
| Patole, SK | 1 |
| Whitehall, JS | 1 |
| Bushnell, PJ | 1 |
| Moser, VC | 1 |
| MacPhail, RC | 1 |
| Oshiro, WM | 1 |
| Derr-Yellin, EC | 1 |
| Phillips, PM | 1 |
| Kodavanti, PR | 1 |
| Schmidt, MH | 1 |
| Lee, T | 1 |
| Van Gent, CM | 1 |
| Sandberg, LB | 1 |
| Boucek, RJ | 1 |
| Littlejohns, CS | 1 |
| Clarke, DJ | 1 |
| Corbett, JA | 1 |
| Miller, JC | 1 |
| Friedhoff, AJ | 1 |
| Scalzo, FM | 3 |
| Newport, GD | 1 |
| Gough, BJ | 2 |
| Ali, SF | 3 |
| Cagiano, R | 1 |
| Barfield, RJ | 1 |
| White, NR | 1 |
| Pleim, ET | 1 |
| Weinstein, M | 1 |
| Cuomo, V | 1 |
| Govoni, S | 1 |
| Missale, C | 1 |
| Memo, M | 1 |
| Fujii, T | 1 |
| Ohtaki, Y | 1 |
| Nakanishi, H | 1 |
| Morimoto, S | 1 |
| Hayashi, K | 1 |
| Yamamoto, N | 1 |
| Watanabe, T | 1 |
| Matsuhashi, K | 1 |
| Takayama, S | 1 |
| Sanberg, PR | 1 |
| Pevsner, J | 1 |
| Autuono, PG | 1 |
| Coyle, JT | 1 |
| Mikołajewska, K | 1 |
| Stragierowicz, J | 1 |
| Gromadzińska, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial of Adjunctive Siltuximab in Schizophrenia[NCT02796859] | Phase 1/Phase 2 | 30 participants (Anticipated) | Interventional | 2016-05-31 | Recruiting | ||
| An Open-Label Trial of Tocilizumab in Schizophrenia[NCT01696929] | Phase 1 | 8 participants (Actual) | Interventional | 2012-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The Brief Assessment of Cognition in Schizophrenia (BACS) is the metric used to characterize cognition in this study. The BACS consists of 6 subscales: Verbal Memory (range 0-75), Working Memory (range 0-28), Motor Speed (range 0-100), Verbal Fluency (measure is total number of words generated in two 60 second trials), Attention and Processing speed (range 0-110), and Executive Function (range 0-22). For each subscale, higher scores reflect better cognition. For each subscale, a Standard Deviation Score was calculated based on normative data (Keefe et al. Norms and standardization of the Brief Assessment of Cognition in Schizophrenia (BACS). Schizophrenia Research 102 (2008) 108-115). The BACS composite score is calculated as the average Standard Deviation Score of the 6 subscale scores. The change in BACS composite score was calculated as the BACS composite score at 8 weeks minus the BACS composite score at baseline. (NCT01696929)
Timeframe: Change in BACS composite score from baseline to 8 weeks
| Intervention | Change in BACS Composite Score (Mean) |
|---|---|
| Tocilizumab | 0.7 |
The Positive and Negative Symptoms Scale (PANSS) is the metric used to characterize psychotic symptoms in this study. The PANSS consists of 30 items, each scored 1-7. The range for the PANSS total score is 30-210. There are 3 subscales - PANSS positive score (range 7-49), PANSS negative score (range 7-49), and PANSS general score (range 16-112). PANSS total score is the summation of these 3 subscales. Higher values for the total and subscale scores reflect more severe psychopathology. A positive change in PANSS total score reflects an increase in psychopathology. A negative change in PANSS total score reflects a decrease in psychopathology. (NCT01696929)
Timeframe: Change in PANSS total score from baseline to 8 weeks
| Intervention | Change in PANSS Total Score (Mean) |
|---|---|
| Tocilizumab | -2.6 |
3 reviews available for haloperidol and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Periadolescence: age-dependent behavior and psychopharmacological responsivity in rats.
Topics: Age Factors; Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain; Cocaine; Exploratory Behavi | 1983 |
Evidence for the involvement of central dopaminergic receptors in the acute and chronic effects induced by barbiturates.
Topics: Adenylyl Cyclases; Animals; Barbiturates; Brain; Chlorpromazine; Dopamine; Drug Interactions; Drug T | 1983 |
Bisphenol A - Application, sources of exposure and potential risks in infants, children and pregnant women.
Topics: Abortion, Spontaneous; Adult; Benzhydryl Compounds; Birth Weight; Child; Child, Preschool; Drinking; | 2015 |
45 other studies available for haloperidol and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment.
Topics: Animals; Antipsychotic Agents; Brain; Cannabidiol; Cerebrovascular Circulation; Disease Models, Anim | 2020 |
Interacting effects of the MAM model of schizophrenia and antipsychotic treatment: Untargeted proteomics approach in adipose tissue.
Topics: Adipose Tissue; Animals; Antipsychotic Agents; Disease Models, Animal; Female; Haloperidol; Intra-Ab | 2021 |
Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice.
Topics: Animals; Aripiprazole; Autism Spectrum Disorder; Dendritic Spines; Disease Models, Animal; Dopamine; | 2017 |
Prenatal one-carbon metabolism dysregulation programs schizophrenia-like deficits.
Topics: Animals; Antipsychotic Agents; Basic Helix-Loop-Helix Transcription Factors; CA1 Region, Hippocampal | 2018 |
Prenatal Exposure to Antipsychotics Disrupts the Plasticity of Dentate Neurons and Memory in Adult Male Mice.
Topics: Animals; Antipsychotic Agents; Dentate Gyrus; Female; Haloperidol; Male; Memory; Mice, Inbred C57BL; | 2019 |
Prenatal treatment with methylazoxymethanol acetate as a neurodevelopmental disruption model of schizophrenia in mice.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Clozapine; Disease Models, Animal; Fe | 2019 |
Transient nephrogenic diabetes insipidus caused by fetal exposure to haloperidol.
Topics: Adult; Antipsychotic Agents; Diabetes Insipidus, Nephrogenic; Female; Haloperidol; Humans; Infant, N | 2014 |
Developmental exposure to purity-controlled polychlorinated biphenyl congeners (PCB74 and PCB95) in rats: effects on brainstem auditory evoked potentials and catalepsy.
Topics: Animals; Brain Stem; Catalepsy; Evoked Potentials, Auditory; Female; Haloperidol; Male; Polychlorina | 2015 |
Clozapine or Haloperidol in rats prenatally exposed to methylazoxymethanol, a compound inducing entorhinal-hippocampal deficits, alter brain and blood neurotrophins' concentrations.
Topics: Alkylating Agents; Animals; Antipsychotic Agents; Body Weight; Brain Chemistry; Clozapine; Entorhina | 2008 |
Evaluating early preventive antipsychotic and antidepressant drug treatment in an infection-based neurodevelopmental mouse model of schizophrenia.
Topics: Age Factors; Amphetamine; Animals; Animals, Newborn; Antidepressive Agents, Second-Generation; Antip | 2010 |
Prenatal lipopolysaccharide reduces motor activity after an immune challenge in adult male offspring.
Topics: Animals; Apomorphine; Brain; Catalepsy; Dopamine; Dopamine Agonists; Dopamine Antagonists; Explorato | 2010 |
Activity-dependent reduction of dopamine D2 receptors during a postnatal critical period of plasticity in rat striatum is not affected by prenatal haloperidol treatment.
Topics: Animals; Behavior, Animal; Binding Sites; Corpus Striatum; Dopamine; Dopamine Antagonists; Female; F | 2011 |
The effect of haloperidol on maternal behavior in WAG/Rij rats and its consequences in the offspring.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anti-Dyskinesia Agents; Brain Waves; D | 2011 |
Effect of prenatal administration of haloperidol, risperidone, quetiapine and olanzapine on spatial learning and retention in adult rats.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Dibenzothiazepines; Drinking; Female; Haloper | 2002 |
Immune activation during pregnancy in rats leads to a postpubertal emergence of disrupted latent inhibition, dopaminergic hyperfunction, and altered limbic morphology in the offspring: a novel neurodevelopmental model of schizophrenia.
Topics: Aging; Amphetamine; Animals; Central Nervous System Stimulants; Clozapine; Corpus Striatum; Disease | 2003 |
Maternal haloperidol therapy associated with dyskinesia in a newborn.
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Clonazepam; Dyskinesia, Drug-Induced; Female; Haloperi | 2003 |
Pharmacological treatment to augment hole board habituation in prenatal Vitamin D-deficient rats.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Exploratory Behavior; Female; Glycine; Habituation, | 2006 |
Neurobehavioral and immunological consequences of prenatal immune activation in rats. Influence of antipsychotics.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Brain; Brain Chemistry; Cytok | 2007 |
Neurobehavioral and immunological consequences of prenatal immune activation in rats. Influence of antipsychotics.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Brain; Brain Chemistry; Cytok | 2007 |
Neurobehavioral and immunological consequences of prenatal immune activation in rats. Influence of antipsychotics.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Brain; Brain Chemistry; Cytok | 2007 |
Neurobehavioral and immunological consequences of prenatal immune activation in rats. Influence of antipsychotics.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Brain; Brain Chemistry; Cytok | 2007 |
Effects of ethanol, given during pregnancy, on the offspring dopaminergic system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dextroamphetamine; Dopamine; Ethanol; Fema | 1983 |
Perinatal dopamine-related drugs demasculinize rats.
Topics: Animals; Animals, Newborn; Apomorphine; Dopamine; Ejaculation; Female; Haloperidol; Male; Methyltyro | 1984 |
Treatment of pregnant rats with haloperidol delays the onset of sexual maturation in female offspring.
Topics: Animals; Body Weight; Female; Haloperidol; Male; Pregnancy; Pregnancy, Animal; Prenatal Exposure Del | 1982 |
Effects of prenatal treatment of rats with haloperidol due to altered drug distribution in neonatal brain.
Topics: Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Brain; Female; Haloperidol; Humans; Kineti | 1981 |
[Pharmacological studies on the functional development of the central nervous system in first generation rats born to phenytoin-treated mothers (author's transl)].
Topics: Animals; Animals, Newborn; Ataxia; Birth Rate; Brain; Catalepsy; Diazepam; Eye; Feeding Behavior; Fe | 1982 |
Changes in dopamine, serotonin and their metabolites in discrete brain areas of rat offspring after in utero exposure to cocaine or related drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amitriptyline; Amygdala; Analysis of Variance; Animals; Brain | 1993 |
Prenatal neuroleptic exposure and growth stunting in the rat: an in vivo and in vitro examination of sensitive periods and possible mechanisms.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Benzazepines; Body Weight; Brain; Dopamine D2 R | 1994 |
Prenatal haloperidol induces a selective reduction in the expression of plasticity-related genes in neonate rat forebrain.
Topics: Actins; Animals; Animals, Newborn; Blotting, Northern; Calmodulin; Cell Adhesion Molecules, Neuronal | 1994 |
Increased appetite after prenatal haloperidol exposure--a case report.
Topics: Appetite; Child; Female; Haloperidol; Humans; Pregnancy; Prenatal Exposure Delayed Effects | 1993 |
Effect of prenatal haloperidol administration on anxiety patterns in rats.
Topics: Animals; Antipsychotic Agents; Anxiety; Exploratory Behavior; Female; Haloperidol; Maze Learning; Pr | 1997 |
Behavioural alterations in rats induced by single prenatal exposure of haloperidol.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Female; Gestational Age; Haloperidol; Male; Materna | 1998 |
Effect of prenatal diazepam, phenobarbital, haloperidol and fluoxetine exposure on foot shock induced aggression in rats.
Topics: Aggression; Animals; Diazepam; Drug Evaluation, Preclinical; Electroshock; Female; Fluoxetine; Halop | 1998 |
Severe hypothermia in a neonate following antenatal exposure to haloperidol.
Topics: Adult; Antipsychotic Agents; Female; Haloperidol; Humans; Hypothermia; Infant, Newborn; Male; Pregna | 2000 |
Neurobehavioral assessments of rats perinatally exposed to a commercial mixture of polychlorinated biphenyls.
Topics: Administration, Oral; Animals; Animals, Newborn; Animals, Suckling; Behavior, Animal; Chlorodiphenyl | 2002 |
Investigation of striatal dopamine D2 receptor acquisition following prenatal neuroleptic exposure.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Corpus Striatum; Dose-Response Relationship, Dr | 1991 |
Haloperidol administration to rats during pregnancy induces permanent alterations in serum lipoprotein patterns of progeny.
Topics: Animals; Body Weight; Brain; Cholesterol; Female; Haloperidol; Lipoproteins; Male; Pregnancy; Prenat | 1991 |
Tourette-like disorder in Asperger's syndrome.
Topics: Adolescent; Autistic Disorder; Female; Haloperidol; Humans; Male; Pregnancy; Prenatal Exposure Delay | 1990 |
Prenatal haloperidol alters the expression of DNA polymerases in brain regions of neonate rats.
Topics: Animals; Animals, Newborn; Brain; DNA-Directed DNA Polymerase; Female; Gene Expression Regulation, E | 1990 |
Prenatal neuroleptic exposure alters postnatal striatal cholinergic activity in the rat.
Topics: Animals; Butaclamol; Choline O-Acetyltransferase; Cholinergic Fibers; Corpus Striatum; Dibenzocycloh | 1986 |
Chronic prenatal haloperidol exposure: lack of effect on presynaptic dopamine autoreceptors.
Topics: 4-Butyrolactone; Animals; Apomorphine; Brain Chemistry; Caudate Nucleus; Chromatography, High Pressu | 1989 |
Neurochemical effects of prenatal haloperidol exposure.
Topics: Amphetamine; Animals; Body Weight; Brain Chemistry; Female; Haloperidol; Male; Pregnancy; Pregnancy | 1989 |
Behavioral effects of prenatal haloperidol exposure.
Topics: Anesthesia; Animals; Avoidance Learning; Behavior, Animal; Conditioning, Operant; Female; Haloperido | 1989 |
Subtle behavioural changes produced in rat pups by in utero exposure to haloperidol.
Topics: Animals; Female; Haloperidol; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Sexual Behav | 1988 |
Effect of lead exposure on dopaminergic receptors in rat striatum and nucleus accumbens.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Corpus Striatum; Female; Haloperidol; Lead Poisoni | 1986 |
Alterations in the thermic response to chlorpromazine in rats exposed prenatally to central nervous system depressants.
Topics: Animals; Body Temperature; Central Nervous System Depressants; Chlorpromazine; Drug Interactions; Et | 1986 |
[Study on the postnatal neuro-behavioral development in rats treated prenatally with drugs acting on the autonomic nervous systems].
Topics: Animals; Atropine; Autonomic Agents; Central Nervous System Diseases; Chlorpromazine; Epinephrine; F | 1985 |
Fetal methylazoxymethanol acetate-induced lesions cause reductions in dopamine receptor-mediated catalepsy and stereotypy.
Topics: Animals; Azo Compounds; Brain; Brain Chemistry; Catalepsy; Choline O-Acetyltransferase; Depression, | 1985 |