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haloperidol and Death, Sudden, Cardiac

haloperidol has been researched along with Death, Sudden, Cardiac in 15 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)

Research Excerpts

ExcerptRelevanceReference
"Treatment with haloperidol has been shown, in studies using death certificates and prescription files, to be associated with an excess of sudden cardiac deaths, and regulatory warnings highlight this risk in patients with dementia."7.81Haloperidol and sudden cardiac death in dementia: autopsy findings in psychiatric inpatients. ( Correll, CU; Grudnikoff, E; Ifteni, P; Kane, JM; Koppel, J; Kremen, N; Manu, P, 2015)
"Droperidol has been an efficacious, inexpensive butyrophenone used since the early 1970s to prevent or treat postoperative nausea and vomiting."4.82Haloperidol: an alternative butyrophenone for nausea and vomiting prophylaxis in anesthesia. ( Smith, JC; Wright, EL, 2005)
"Treatment with haloperidol has been shown, in studies using death certificates and prescription files, to be associated with an excess of sudden cardiac deaths, and regulatory warnings highlight this risk in patients with dementia."3.81Haloperidol and sudden cardiac death in dementia: autopsy findings in psychiatric inpatients. ( Correll, CU; Grudnikoff, E; Ifteni, P; Kane, JM; Koppel, J; Kremen, N; Manu, P, 2015)
"To compare the rate of ventricular arrhythmia, sudden death and unexplained or unattended death among users of thioridazine and haloperidol."3.72Comparative cardiac safety of low-dose thioridazine and low-dose haloperidol. ( Bilker, WB; Glasser, DB; Hennessy, S; Kimmel, SE; Knauss, JS; Margolis, DJ; Morrison, MF; Reynolds, RF; Strom, BL, 2004)
"Patients with schizophrenia treated with clozapine, haloperidol, risperidone, or thioridazine; a control group of patients with glaucoma; and a control group of patients with psoriasis."3.71Cardiac arrest and ventricular arrhythmia in patients taking antipsychotic drugs: cohort study using administrative data. ( Bilker, WB; Glasser, DB; Hennessy, S; Kimmel, SE; Knauss, JS; Margolis, DJ; Morrison, MF; Reynolds, RF; Strom, BL, 2002)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.67)18.2507
2000's10 (66.67)29.6817
2010's4 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ifteni, P1
Grudnikoff, E1
Koppel, J1
Kremen, N1
Correll, CU1
Kane, JM1
Manu, P1
Muzyk, AJ2
Rayfield, A2
Revollo, JY1
Heinz, H2
Gagliardi, JP2
Rivelli, SK1
Jiang, W1
Cheung, D1
Wolfe, B1
Wald, H1
Cumbler, E1
Veltkamp, R1
Vorel-Havelkova, E1
Brombacher, PJ1
Hennessy, S2
Bilker, WB2
Knauss, JS2
Margolis, DJ2
Kimmel, SE2
Reynolds, RF2
Glasser, DB2
Morrison, MF2
Strom, BL2
Zareba, W1
Lin, DA1
Schoenholtz, JC1
Smith, JC1
Wright, EL1
Pohjola-Sintonen, S1
Metsäniitty, J1
Remijnse, PL1
Eeckhout, AM1
van Guldener, C1
Su, KP1
Chang, HC1
Shen, WW1
Taylor, DM1

Reviews

2 reviews available for haloperidol and Death, Sudden, Cardiac

ArticleYear
Antipsychotic drugs and QT interval prolongation.
    The Psychiatric quarterly, 2003,Fall, Volume: 74, Issue:3

    Topics: Age Factors; Algorithms; Antipsychotic Agents; Benzodiazepines; Death, Sudden, Cardiac; Dopamine Ant

2003
Haloperidol: an alternative butyrophenone for nausea and vomiting prophylaxis in anesthesia.
    AANA journal, 2005, Volume: 73, Issue:4

    Topics: Antiemetics; Butyrophenones; Death, Sudden, Cardiac; Droperidol; Haloperidol; Humans; Postoperative

2005

Other Studies

13 other studies available for haloperidol and Death, Sudden, Cardiac

ArticleYear
Haloperidol and sudden cardiac death in dementia: autopsy findings in psychiatric inpatients.
    International journal of geriatric psychiatry, 2015, Volume: 30, Issue:12

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Autopsy; Death, Sudden, Cardiac; Dementia; Female; Ha

2015
Examination of baseline risk factors for QTc interval prolongation in patients prescribed intravenous haloperidol.
    Drug safety, 2012, Jul-01, Volume: 35, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Cohort Studies; Death, Sudden, Cardiac; Female; Haloperidol; Hosp

2012
A computerized physician order entry set designed to improve safety of intravenous haloperidol utilization: a retrospective study in agitated hospitalized patients.
    Drug safety, 2012, Sep-01, Volume: 35, Issue:9

    Topics: Aged; Antipsychotic Agents; Cohort Studies; Death, Sudden, Cardiac; Electrocardiography; Female; Hal

2012
Unsafe use of intravenous haloperidol: evaluation of recommendation-concordant care in hospitalized elderly adults.
    Journal of the American Geriatrics Society, 2013, Volume: 61, Issue:1

    Topics: Age Factors; Aged; Antipsychotic Agents; Colorado; Death, Sudden, Cardiac; Delirium; Electrocardiogr

2013
[Sudden death following a single oral administration of haloperidol].
    Nederlands tijdschrift voor geneeskunde, 2002, Jul-06, Volume: 146, Issue:27

    Topics: Administration, Oral; Alcoholism; Antipsychotic Agents; Death, Sudden, Cardiac; Haloperidol; Humans;

2002
[Sudden death following a single oral administration of haloperidol].
    Nederlands tijdschrift voor geneeskunde, 2002, Jul-06, Volume: 146, Issue:27

    Topics: Antipsychotic Agents; Death, Sudden, Cardiac; Dose-Response Relationship, Drug; Drug Interactions; F

2002
Cardiac arrest and ventricular arrhythmia in patients taking antipsychotic drugs: cohort study using administrative data.
    BMJ (Clinical research ed.), 2002, Nov-09, Volume: 325, Issue:7372

    Topics: Adult; Aged; Antipsychotic Agents; Arrhythmias, Cardiac; Clozapine; Cohort Studies; Confidence Inter

2002
Comparative cardiac safety of low-dose thioridazine and low-dose haloperidol.
    British journal of clinical pharmacology, 2004, Volume: 58, Issue:1

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Arrhythmias, Cardiac; Child; Child, Preschool; Cohort

2004
Oral erythromycin and the risk of sudden death.
    The New England journal of medicine, 2005, Jan-20, Volume: 352, Issue:3

    Topics: Anti-Bacterial Agents; Antipsychotic Agents; Cytochrome P-450 Enzyme Inhibitors; Death, Sudden, Card

2005
[Treatment of alcohol delirium can cause sudden cardiac death].
    Duodecim; laaketieteellinen aikakauskirja, 1997, Volume: 113, Issue:13

    Topics: Adult; Alcohol Withdrawal Delirium; Antipsychotic Agents; Death, Sudden, Cardiac; Haloperidol; Human

1997
[Sudden death following a single oral administration of haloperidol].
    Nederlands tijdschrift voor geneeskunde, 2002, Apr-20, Volume: 146, Issue:16

    Topics: Administration, Oral; Adult; Antipsychotic Agents; Arrhythmias, Cardiac; Cardiomyopathies; Death, Su

2002
Prolongation of QTc interval and antipsychotics.
    The American journal of psychiatry, 2002, Volume: 159, Issue:6

    Topics: Antipsychotic Agents; Death, Sudden, Cardiac; Haloperidol; Humans; Long QT Syndrome; Thioridazine; T

2002
Prolongation of QTc interval and antipsychotics.
    The American journal of psychiatry, 2002, Volume: 159, Issue:6

    Topics: Antipsychotic Agents; Death, Sudden, Cardiac; Drug Administration Schedule; Drug Labeling; Drug Moni

2002