Page last updated: 2024-10-28

haloperidol and Coxarthrosis

haloperidol has been researched along with Coxarthrosis in 1 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Research Excerpts

ExcerptRelevanceReference
"To study the effectiveness of haloperidol prophylaxis on incidence, severity, and duration of postoperative delirium in elderly hip-surgery patients at risk for delirium."9.11Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study. ( Bogaards, MJ; Burger, BJ; de Jonghe, JF; Egberts, TC; Eikelenboom, P; Kalisvaart, KJ; van Gool, WA; Vreeswijk, R, 2005)
"To study the effectiveness of haloperidol prophylaxis on incidence, severity, and duration of postoperative delirium in elderly hip-surgery patients at risk for delirium."5.11Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study. ( Bogaards, MJ; Burger, BJ; de Jonghe, JF; Egberts, TC; Eikelenboom, P; Kalisvaart, KJ; van Gool, WA; Vreeswijk, R, 2005)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kalisvaart, KJ1
de Jonghe, JF1
Bogaards, MJ1
Vreeswijk, R1
Egberts, TC1
Burger, BJ1
Eikelenboom, P1
van Gool, WA1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Dexmedetomidine Combined With Ropivacaine for Postoperative Continuous Femoral Nerve Block on Postoperative Delirium and Long-term Oucomes in Elderly Patients After Single Knee Arthroplasty[NCT03629483]Phase 4736 participants (Anticipated)Interventional2018-12-10Suspended (stopped due to Trial stopped by the sponsor because of no funding.)
Usefulness of Bright Light Therapy in the Prevention of Delirium in Patients Undergoing Hematopoietic Stem Cell Transplant (HSCT)[NCT01700816]40 participants (Actual)Interventional2012-10-31Terminated (stopped due to Low incidence of delirium.)
Dynamic Light Application to Prevent ICU Acquired Delirium[NCT01274819]1,000 participants (Actual)Interventional2011-07-31Completed
Impact of Dexmedetomidine Supplemented Intravenous Analgesia on Postoperative Delirium and Long-term Outcomes in Elderly After Orthopedic Surgery: A Multicenter, Double-blinded, Randomized Controlled Trial[NCT03629262]Phase 4712 participants (Actual)Interventional2018-10-28Active, not recruiting
Impact of Dexmedetomidine Supplemented Analgesia on Delirium and Long-term Outcomes in Elderly After Hip Fracture Surgery: A Multicenter, Double-blinded, Randomized Controlled Trial[NCT04955249]Phase 41,440 participants (Anticipated)Interventional2021-11-18Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Hematocrit (HCT)

Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

Interventionvolume percentage (vol%) of red blood ce (Median)
Bright Light Therapy28.20
Sham Light26.70

Hemoglobin (HGB)

Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

Interventiong/dl (Median)
Bright Light Therapy9.70
Sham Light9.55

Hospital Length of Stay

(NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

Interventiondays (Median)
Bright Light Therapy18
Sham Light18.5

Number of Participants Who Developed Delirium Based on Meeting Criteria on the Delirium Rating Scale and/or Memorial Delirium Assessment Scale

Monday, Wednesday, and Friday assessments will begin after beginning light therapy and include the Delirium Rating Scale-Revised-98 (DRS-98)and Memorial Delirium Assessment Scale (MDAS) (NCT01700816)
Timeframe: From hospital admission until the date of first documented delirium, assessed up to 28 days post-transplant

InterventionParticipants (Count of Participants)
Bright Light Therapy1
Sham Light0

Platelet Count

Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

Interventionthousand cells/uL (Median)
Bright Light Therapy39
Sham Light33.5

Red Blood Cells (RBC)

Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

InterventionM/uL (Median)
Bright Light Therapy3.21
Sham Light2.93

Severity of Delirium Episodes: Memorial Delirium Assessment Scale (MDAS)

"Monday, Wednesday, and Friday assessments of the Memorial Delirium Assessment Scale (MDAS); Patients will receive assessments after beginning light therapy until day 28 post-transplant or discharge, whichever comes first.~10 item scale Items are rated on a four-point scale from 0 (none) to 3 (severe) depending on the level of impairment, rendering a maximum possible score of 30.~A score of 13 has been recommended as a cut-off for establishing the diagnosis of delirium" (NCT01700816)
Timeframe: From first documented episode of delirium until discharge from the hospital, assessed up to 28 days post-transplant

Interventionunits on a scale (Number)
Bright Light Therapy18

White Blood Cells (WBC)

Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

InterventionK/uL (Median)
Bright Light Therapy2.30
Sham Light4.75

Serum Creatinine and Blood Urea Nitrogen (BUN)

Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

,
Interventionmg/dl (Median)
Serum CreatinineBlood Urea Nitrogen (BUN)
Bright Light Therapy0.669
Sham Light0.758.5

Sodium (Na), Potassium (K), Chloride (Cl), and Carbon Dioxide (CO2)

Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT (Hematopoietic Stem Cell Transplantation). (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant

,
Interventionmmol/L (Median)
Sodium (Na)Potassium (K)Chloride (Cl)Carbon Dioxide (CO2)
Bright Light Therapy1393.610524.9
Sham Light138.03.80103.025.10

Trials

1 trial available for haloperidol and Coxarthrosis

ArticleYear
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H

2005