haloperidol has been researched along with Complication, Postoperative in 61 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is limited but promising evidence that haloperidol and ketamine can be used to prevent delirium." | 9.27 | Baden Prevention and Reduction of Incidence of Postoperative Delirium Trial (PRIDe): a phase IV multicenter, randomized, placebo-controlled, double-blind clinical trial of ketamine versus haloperidol for prevention of postoperative delirium. ( Blum, A; Hollinger, A; Riegger, H; Seifert, B; Siegemund, M; Toft, K; Zehnder, T, 2018) |
| "The aim of this study was to evaluate the safety and efficacy of the early administration haloperidol in preventing the aggravation of postoperative delirium in elderly patients." | 9.24 | Haloperidol prophylaxis for preventing aggravation of postoperative delirium in elderly patients: a randomized, open-label prospective trial. ( Akiyama, H; Ando, M; Fujishiro, K; Fukata, S; Hattori, H; Kawabata, Y; Kitagawa, Y; Kuroiwa, K; Takemura, M, 2017) |
| "The preventive administration of low-dose haloperidol did not induce any adverse events, but also did not significantly decrease the incidence or severity of postoperative delirium or shorten its persistence." | 9.19 | Haloperidol prophylaxis does not prevent postoperative delirium in elderly patients: a randomized, open-label prospective trial. ( Akiyama, H; Ando, M; Fujisiro, K; Fukata, S; Hattori, H; Katagawa, Y; Kawabata, Y; Kawamura, T; Kuroiwa, K; Terabe, Y, 2014) |
| "Patients were randomized into 2 groups; in group 1, patients received 5mg of haloperidol intramuscularly and in group 2, patients received 5mg of morphine sulfate intramuscularly to control delirium symptoms." | 9.17 | Morphine is a reasonable alternative to haloperidol in the treatment of postoperative hyperactive-type delirium after cardiac surgery. ( Akgün, S; Atalan, N; Başaran, C; Efe Sevim, M; Fazlıoğulları, O, 2013) |
| "For elderly patients admitted to intensive care unit after noncardiac surgery, short-term prophylactic administration of low-dose intravenous haloperidol significantly decreased the incidence of postoperative delirium." | 9.16 | Haloperidol prophylaxis decreases delirium incidence in elderly patients after noncardiac surgery: a randomized controlled trial*. ( Chen, KS; Gu, XE; Li, HL; Li, SL; Wang, DX; Wang, W; Yao, GQ; Zhu, SN; Zhu, X, 2012) |
| "Both ondasetron and haloperidol had very good delirium controlling effects, without statistically significant differences." | 9.16 | Ondasetron versus haloperidol for the treatment of postcardiotomy delirium: a prospective, randomized, double-blinded study. ( Daskalopoulos, ME; Gogaki, E; Papaliagkas, V; Parisis, C; Sataitidis, I; Tagarakis, GI; Tsagalas, I; Tsilimingas, NB; Tsolaki, F; Tsolaki, M; Voucharas, C, 2012) |
| "Low-dose haloperidol prophylactic treatment demonstrated no efficacy in reducing the incidence of postoperative delirium." | 9.11 | Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study. ( Bogaards, MJ; Burger, BJ; de Jonghe, JF; Egberts, TC; Eikelenboom, P; Kalisvaart, KJ; van Gool, WA; Vreeswijk, R, 2005) |
| "Sixty-two postoperative patients were admitted to a double-blind study to compare the therapeutic effectiveness of a single intramuscular injection of 1 mg of haloperidol with that of a placebo for the relief of vomiting and nausea following surgical procedures." | 9.04 | The use of haloperidol for treatment of postoperative nausea and vomiting--a double-blind placebo-controlled trial. ( Barton, MD; Cohen, PJ; Libonati, M, 1975) |
| "In this study, the limited available data revealed that prophylaxis haloperidol at a dose of ≥5 mg/day might help reduce delirium in adult surgical patients." | 8.98 | Effects of Haloperidol on Delirium in Adult Patients: A Systematic Review and Meta-Analysis. ( Ji, FH; Meng, XW; Peng, K; Shen, YZ; Zhang, J, 2018) |
| "Adjunctive low-dose haloperidol prophylaxis reduces delirium severity, duration, and subsequent hospitalization length in elderly at-risk patients." | 8.84 | Adjunctive haloperidol prophylaxis reduces postoperative delirium severity and duration in at-risk elderly patients. ( Caselli, RJ; Demaerschalk, BM; Schrader, SL; Wellik, KE; Wingerchuk, DM; Woodruff, BK, 2008) |
| " In this regard, hyperventilation leading to apnea and desaturation is a rare entity." | 7.91 | A case of hyperventilation leading to apnea and desaturation in PACU. ( Baral, P; Poudel, A; Subedi, A; Thapa, P, 2019) |
| " Dexmedetomidine significantly decreased the ICU LOS and ICU LOS after the occurrence of delirium compared to haloperidol (13." | 7.83 | Use of Dexmedetomidine in Liver Transplant Recipients With Postoperative Agitated Delirium. ( Choi, JY; Gwak, MS; Joh, JW; Kim, GS; Kim, JM; Kim, SJ; Ko, JS; Kwon, CH; Lee, S; Lee, SK; Park, JB, 2016) |
| "There is limited but promising evidence that haloperidol and ketamine can be used to prevent delirium." | 5.27 | Baden Prevention and Reduction of Incidence of Postoperative Delirium Trial (PRIDe): a phase IV multicenter, randomized, placebo-controlled, double-blind clinical trial of ketamine versus haloperidol for prevention of postoperative delirium. ( Blum, A; Hollinger, A; Riegger, H; Seifert, B; Siegemund, M; Toft, K; Zehnder, T, 2018) |
| "To assess the efficacy of haloperidol in reducing postoperative delirium in individuals undergoing thoracic surgery." | 5.27 | Preventing Postoperative Delirium After Major Noncardiac Thoracic Surgery-A Randomized Clinical Trial. ( Boustani, MA; Campbell, NL; Fuchita, M; Gao, S; Kesler, K; Khan, BA; Khan, SH; Perkins, AJ; Wang, S; Weber, DJ; Zarzaur, BL, 2018) |
| "The aim of this study was to evaluate the safety and efficacy of the early administration haloperidol in preventing the aggravation of postoperative delirium in elderly patients." | 5.24 | Haloperidol prophylaxis for preventing aggravation of postoperative delirium in elderly patients: a randomized, open-label prospective trial. ( Akiyama, H; Ando, M; Fujishiro, K; Fukata, S; Hattori, H; Kawabata, Y; Kitagawa, Y; Kuroiwa, K; Takemura, M, 2017) |
| "The preventive administration of low-dose haloperidol did not induce any adverse events, but also did not significantly decrease the incidence or severity of postoperative delirium or shorten its persistence." | 5.19 | Haloperidol prophylaxis does not prevent postoperative delirium in elderly patients: a randomized, open-label prospective trial. ( Akiyama, H; Ando, M; Fujisiro, K; Fukata, S; Hattori, H; Katagawa, Y; Kawabata, Y; Kawamura, T; Kuroiwa, K; Terabe, Y, 2014) |
| "Patients were randomized into 2 groups; in group 1, patients received 5mg of haloperidol intramuscularly and in group 2, patients received 5mg of morphine sulfate intramuscularly to control delirium symptoms." | 5.17 | Morphine is a reasonable alternative to haloperidol in the treatment of postoperative hyperactive-type delirium after cardiac surgery. ( Akgün, S; Atalan, N; Başaran, C; Efe Sevim, M; Fazlıoğulları, O, 2013) |
| "For elderly patients admitted to intensive care unit after noncardiac surgery, short-term prophylactic administration of low-dose intravenous haloperidol significantly decreased the incidence of postoperative delirium." | 5.16 | Haloperidol prophylaxis decreases delirium incidence in elderly patients after noncardiac surgery: a randomized controlled trial*. ( Chen, KS; Gu, XE; Li, HL; Li, SL; Wang, DX; Wang, W; Yao, GQ; Zhu, SN; Zhu, X, 2012) |
| "Both ondasetron and haloperidol had very good delirium controlling effects, without statistically significant differences." | 5.16 | Ondasetron versus haloperidol for the treatment of postcardiotomy delirium: a prospective, randomized, double-blinded study. ( Daskalopoulos, ME; Gogaki, E; Papaliagkas, V; Parisis, C; Sataitidis, I; Tagarakis, GI; Tsagalas, I; Tsilimingas, NB; Tsolaki, F; Tsolaki, M; Voucharas, C, 2012) |
| " Hip surgery patients (n = 112) aged 70 years and older, who participated in a controlled clinical trial of haloperidol prophylaxis for delirium, were followed for an average of 30 months after discharge." | 5.13 | Long-term cognitive outcome of delirium in elderly hip surgery patients. A prospective matched controlled study over two and a half years. ( de Jonghe, JF; Eikelenboom, P; Kalisvaart, KJ; Kat, MG; van der Ploeg, T; van Gool, WA; Vreeswijk, R, 2008) |
| "Low-dose haloperidol prophylactic treatment demonstrated no efficacy in reducing the incidence of postoperative delirium." | 5.11 | Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study. ( Bogaards, MJ; Burger, BJ; de Jonghe, JF; Egberts, TC; Eikelenboom, P; Kalisvaart, KJ; van Gool, WA; Vreeswijk, R, 2005) |
| "Sixty-two postoperative patients were admitted to a double-blind study to compare the therapeutic effectiveness of a single intramuscular injection of 1 mg of haloperidol with that of a placebo for the relief of vomiting and nausea following surgical procedures." | 5.04 | The use of haloperidol for treatment of postoperative nausea and vomiting--a double-blind placebo-controlled trial. ( Barton, MD; Cohen, PJ; Libonati, M, 1975) |
| "In this study, the limited available data revealed that prophylaxis haloperidol at a dose of ≥5 mg/day might help reduce delirium in adult surgical patients." | 4.98 | Effects of Haloperidol on Delirium in Adult Patients: A Systematic Review and Meta-Analysis. ( Ji, FH; Meng, XW; Peng, K; Shen, YZ; Zhang, J, 2018) |
| "The use of antipsychotics for surgical ICU patients and dexmedetomidine for mechanically ventilated patients as a preventive strategy may reduce the prevalence of delirium in the ICU." | 4.91 | Pharmacologic prevention and treatment of delirium in intensive care patients: A systematic review. ( Bozza, FA; do Brasil, PE; Ely, EW; Salluh, JI; Serafim, RB; Soares, M; Tura, BR, 2015) |
| "Adjunctive low-dose haloperidol prophylaxis reduces delirium severity, duration, and subsequent hospitalization length in elderly at-risk patients." | 4.84 | Adjunctive haloperidol prophylaxis reduces postoperative delirium severity and duration in at-risk elderly patients. ( Caselli, RJ; Demaerschalk, BM; Schrader, SL; Wellik, KE; Wingerchuk, DM; Woodruff, BK, 2008) |
| " In this regard, hyperventilation leading to apnea and desaturation is a rare entity." | 3.91 | A case of hyperventilation leading to apnea and desaturation in PACU. ( Baral, P; Poudel, A; Subedi, A; Thapa, P, 2019) |
| " Dexmedetomidine significantly decreased the ICU LOS and ICU LOS after the occurrence of delirium compared to haloperidol (13." | 3.83 | Use of Dexmedetomidine in Liver Transplant Recipients With Postoperative Agitated Delirium. ( Choi, JY; Gwak, MS; Joh, JW; Kim, GS; Kim, JM; Kim, SJ; Ko, JS; Kwon, CH; Lee, S; Lee, SK; Park, JB, 2016) |
| "Secondary analysis of haloperidol prophylaxis for delirium clinical trial data." | 3.77 | Anesthesia and postoperative delirium in older adults undergoing hip surgery. ( de Jonghe, JF; Eikelenboom, P; Groot, E; Kalisvaart, KJ; Ploeg, TV; Schmand, B; Slor, CJ; Snoeck, M; van Gool, WA; Vreeswijk, R, 2011) |
| "this is a secondary analysis based on data from a controlled clinical trial evaluating efficacy of haloperidol prophylaxis for delirium conducted in a large medical school-affiliated general hospital in Alkmaar, The Netherlands." | 3.77 | Mortality associated with delirium after hip-surgery: a 2-year follow-up study. ( de Jonghe, JF; Eikelenboom, P; Kalisvaart, KJ; Kat, MG; van der Ploeg, T; van Gool, WA; Vreeswijk, R, 2011) |
| "Neuroleptic malignant syndrome occurred in a 71-year-old man on haloperidol therapy for mild depressive dementia." | 3.71 | Neuroleptic malignant syndrome: uncommon postoperative diagnostic dilemma. ( Bhan, S; Kulkarni, V; Mehta, Y; Sharma, KK; Suri, ML; Trehan, N, 2002) |
| " Administration of large intravenous doses of haloperidol was necessary for control of psychomotor agitation due to delirium." | 3.70 | Torsades de pointes secondary to intravenous haloperidol after coronary bypass grafting surgery. ( Bélisle, S; Carrier, M; Cartier, R; Denault, AY; Perrault, LP, 2000) |
| " Treatment with antipsychotics in this limited pilot trial did not improve the number of days alive without delirium or coma, nor did it increase adverse outcomes." | 2.75 | Feasibility, efficacy, and safety of antipsychotics for intensive care unit delirium: the MIND randomized, placebo-controlled trial. ( Bernard, GR; Canonico, AE; Carson, SS; Dittus, RS; Ely, EW; Girard, TD; Meltzer, HY; Pandharipande, PP; Pun, BT; Schmidt, GA; Shintani, AK; Thompson, JL; Wright, PE, 2010) |
| "Postoperative delirium is the most common neurological complication of cardiac surgery." | 1.48 | The influence of oxygen delivery during cardiopulmonary bypass on the incidence of delirium in CABG patients; a retrospective study. ( Golab, H; Leenders, J; Overdevest, E; van Straten, B, 2018) |
| "Strategies to prevent and treat delirium during hospitalization for hip fracture have been less studied." | 1.40 | [Delirium prevention and treatment in elderly hip fracture]. ( Formiga, F; Robles, MJ; Vidán, MT, 2014) |
| "Hyperventilation syndrome has often occurred as a reaction to anxiety and stress." | 1.35 | [Hyperventilation syndrome before induction of and after awakening from general anesthesia]. ( Hanaoka, K; Honda, M; Itou, Y; Mizuno, J; Momoeda, K; Morita, S, 2009) |
| " Carbamazepine at a dosage of 800 mg daily was the most effective medication used." | 1.33 | Auditory hallucinations after right temporal gyri resection. ( Brennan, DM; Stewart, B, 2005) |
| "A case is reported, in which fatal pulmonary embolism complicated the course of a neuroleptic malignant syndrome (NMS)." | 1.28 | [Malignant neuroleptic syndrome: complete anticoagulant treatment or not?]. ( van Agtmael, MA; van Harten, PN, 1992) |
| "The neuroleptic malignant syndrome is a serious and potentially fatal complication of neuroleptic and other dopamine antagonist drugs that are commonly used in symptom control in advanced cancer." | 1.28 | The neuroleptic malignant syndrome. ( O'Neill, WM, 1990) |
| "Six patients who had had severe migraine attacks after previous operations were given sedative before operation and dextrose 50 g and haloperidol 1." | 1.26 | Migraine and surgery. Avoidance of trigger mechanisms. ( Fell, RH, 1980) |
| "Prochlorperazine has an intermediate onset of action and droperidol is the slowest of the three compounds but the only one to provide significant anti-emesis 4-24 hours following administration." | 1.26 | Comparison of droperidol, haloperidol and prochlorperazine as postoperative anti-emetics. ( Bennett, G; Loeser, EA; Machin, R; Stanley, TH, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (14.75) | 18.7374 |
| 1990's | 8 (13.11) | 18.2507 |
| 2000's | 15 (24.59) | 29.6817 |
| 2010's | 28 (45.90) | 24.3611 |
| 2020's | 1 (1.64) | 2.80 |
| Authors | Studies |
|---|---|
| Thapa, P | 1 |
| Subedi, A | 1 |
| Poudel, A | 1 |
| Baral, P | 1 |
| Park, SK | 1 |
| Lim, T | 1 |
| Cho, H | 1 |
| Yoon, HK | 1 |
| Lee, HJ | 1 |
| Lee, JH | 1 |
| Yoo, S | 1 |
| Kim, JT | 1 |
| Kim, WH | 1 |
| Regan, DW | 1 |
| Kashiwagi, D | 1 |
| Dougan, B | 1 |
| Sundsted, K | 1 |
| Mauck, K | 1 |
| Riegger, H | 1 |
| Hollinger, A | 1 |
| Seifert, B | 1 |
| Toft, K | 1 |
| Blum, A | 1 |
| Zehnder, T | 1 |
| Siegemund, M | 1 |
| Shen, YZ | 1 |
| Peng, K | 1 |
| Zhang, J | 1 |
| Meng, XW | 1 |
| Ji, FH | 1 |
| Leenders, J | 1 |
| Overdevest, E | 1 |
| van Straten, B | 1 |
| Golab, H | 1 |
| Siuciuno, T | 1 |
| Shimakawa, N | 1 |
| Shibuya, H | 1 |
| Suzuki, H | 1 |
| Ozawa, A | 1 |
| Moriwaki, K | 1 |
| Hirao, M | 1 |
| Khan, BA | 1 |
| Perkins, AJ | 1 |
| Campbell, NL | 1 |
| Gao, S | 1 |
| Khan, SH | 1 |
| Wang, S | 1 |
| Fuchita, M | 1 |
| Weber, DJ | 1 |
| Zarzaur, BL | 1 |
| Boustani, MA | 1 |
| Kesler, K | 1 |
| Robles, MJ | 1 |
| Formiga, F | 1 |
| Vidán, MT | 1 |
| Atalan, N | 1 |
| Efe Sevim, M | 1 |
| Akgün, S | 1 |
| Fazlıoğulları, O | 1 |
| Başaran, C | 1 |
| Fukata, S | 2 |
| Kawabata, Y | 2 |
| Fujisiro, K | 1 |
| Katagawa, Y | 1 |
| Kuroiwa, K | 2 |
| Akiyama, H | 2 |
| Terabe, Y | 1 |
| Ando, M | 2 |
| Kawamura, T | 1 |
| Hattori, H | 2 |
| Yara, M | 1 |
| Tomino, M | 1 |
| Miyata, K | 1 |
| Ishida, Y | 1 |
| Saiki, I | 1 |
| Seta, N | 1 |
| Hara, N | 1 |
| Uchino, H | 1 |
| Serafim, RB | 1 |
| Bozza, FA | 1 |
| Soares, M | 1 |
| do Brasil, PE | 1 |
| Tura, BR | 1 |
| Ely, EW | 2 |
| Salluh, JI | 1 |
| Choi, JY | 1 |
| Kim, JM | 1 |
| Kwon, CH | 1 |
| Joh, JW | 1 |
| Lee, S | 1 |
| Park, JB | 1 |
| Ko, JS | 1 |
| Gwak, MS | 1 |
| Kim, GS | 1 |
| Kim, SJ | 1 |
| Lee, SK | 1 |
| Park, JI | 1 |
| Fujishiro, K | 1 |
| Kitagawa, Y | 1 |
| Takemura, M | 1 |
| Freter, S | 1 |
| Koller, K | 1 |
| Dunbar, M | 1 |
| MacKnight, C | 1 |
| Rockwood, K | 1 |
| Kat, MG | 3 |
| Vreeswijk, R | 5 |
| de Jonghe, JF | 5 |
| van der Ploeg, T | 3 |
| van Gool, WA | 5 |
| Eikelenboom, P | 5 |
| Kalisvaart, KJ | 5 |
| Fricchione, GL | 1 |
| Nejad, SH | 1 |
| Esses, JA | 1 |
| Cummings, TJ | 1 |
| Querques, J | 1 |
| Cassem, NH | 1 |
| Murray, GB | 1 |
| Narayanan, D | 1 |
| Varghese, ST | 1 |
| Dinesh, D | 1 |
| Mizuno, J | 1 |
| Morita, S | 1 |
| Itou, Y | 1 |
| Honda, M | 1 |
| Momoeda, K | 1 |
| Hanaoka, K | 1 |
| Balas, MC | 1 |
| Girard, TD | 1 |
| Pandharipande, PP | 1 |
| Carson, SS | 1 |
| Schmidt, GA | 1 |
| Wright, PE | 1 |
| Canonico, AE | 1 |
| Pun, BT | 1 |
| Thompson, JL | 1 |
| Shintani, AK | 1 |
| Meltzer, HY | 1 |
| Bernard, GR | 1 |
| Dittus, RS | 1 |
| Özdemir, B | 1 |
| Çelik, C | 1 |
| Çinar, A | 1 |
| Özşahin, A | 1 |
| Slor, CJ | 1 |
| Groot, E | 1 |
| Ploeg, TV | 1 |
| Snoeck, M | 1 |
| Schmand, B | 1 |
| Wang, W | 1 |
| Li, HL | 1 |
| Wang, DX | 1 |
| Zhu, X | 1 |
| Li, SL | 1 |
| Yao, GQ | 1 |
| Chen, KS | 1 |
| Gu, XE | 1 |
| Zhu, SN | 1 |
| Caplan, JP | 1 |
| Tagarakis, GI | 1 |
| Voucharas, C | 1 |
| Tsolaki, F | 1 |
| Daskalopoulos, ME | 1 |
| Papaliagkas, V | 1 |
| Parisis, C | 1 |
| Gogaki, E | 1 |
| Tsagalas, I | 1 |
| Sataitidis, I | 1 |
| Tsolaki, M | 1 |
| Tsilimingas, NB | 1 |
| Colombo, R | 1 |
| Corona, A | 1 |
| Praga, F | 1 |
| Minari, C | 1 |
| Giannotti, C | 1 |
| Castelli, A | 1 |
| Raimondi, F | 1 |
| Reade, MC | 1 |
| Bhan, S | 1 |
| Kulkarni, V | 1 |
| Mehta, Y | 1 |
| Sharma, KK | 1 |
| Trehan, N | 1 |
| Suri, ML | 1 |
| Stanley, KM | 1 |
| Amabile, CM | 1 |
| Simpson, KN | 1 |
| Couillard, D | 1 |
| Norcross, ED | 1 |
| Worrall, CL | 1 |
| Kudoh, A | 1 |
| Katagai, H | 1 |
| Takase, H | 1 |
| Takazawa, T | 1 |
| Young, CC | 1 |
| Lujan, E | 1 |
| Stewart, B | 1 |
| Brennan, DM | 1 |
| Bogaards, MJ | 1 |
| Egberts, TC | 1 |
| Burger, BJ | 1 |
| Wang, MD | 1 |
| Seitz, D | 1 |
| Gill, SS | 1 |
| Dijkstra, M | 1 |
| van Dis, H | 1 |
| Schrader, SL | 1 |
| Wellik, KE | 1 |
| Demaerschalk, BM | 1 |
| Caselli, RJ | 1 |
| Woodruff, BK | 1 |
| Wingerchuk, DM | 1 |
| Hales, RE | 1 |
| Holtz, JL | 1 |
| Cassem, EH | 1 |
| Magni, G | 1 |
| De Leo, D | 1 |
| Fell, RH | 1 |
| Tamai, S | 1 |
| Soares, JC | 1 |
| Fráguas Júnior, R | 1 |
| Spies, CD | 1 |
| Dubisz, N | 1 |
| Funk, W | 1 |
| Blum, S | 1 |
| Müller, C | 1 |
| Rommelspacher, H | 1 |
| Brummer, G | 1 |
| Specht, M | 1 |
| Hannemann, L | 1 |
| Striebel, HW | 1 |
| Manos, PJ | 1 |
| Wu, R | 1 |
| Gherpelli, JL | 1 |
| Azeka, E | 1 |
| Riso, A | 1 |
| Atik, E | 1 |
| Ebaid, M | 1 |
| Barbero-Marcial, M | 1 |
| Perrault, LP | 1 |
| Denault, AY | 1 |
| Carrier, M | 1 |
| Cartier, R | 1 |
| Bélisle, S | 1 |
| Loeser, EA | 1 |
| Bennett, G | 1 |
| Stanley, TH | 1 |
| Machin, R | 1 |
| Barton, MD | 1 |
| Libonati, M | 1 |
| Cohen, PJ | 1 |
| van Agtmael, MA | 1 |
| van Harten, PN | 1 |
| Heil, T | 1 |
| Martens, D | 1 |
| Eyrich, K | 1 |
| Gribbin, JC | 1 |
| Cox, CJ | 1 |
| O'Neill, WM | 1 |
| Moulaert, P | 1 |
| Mahmoodian, S | 1 |
| Walsh, AC | 1 |
| Walsh, BH | 1 |
| De Vries, PM | 1 |
| Karaskov, A | 1 |
| Bogachev-Prokophiev, A | 1 |
| Sharifulin, R | 1 |
| Zheleznev, S | 1 |
| Demin, I | 1 |
| Pivkin, A | 1 |
| Zhuravleva, I | 1 |
| Oshino, S | 1 |
| Saitoh, Y | 1 |
| Yoshimine, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Baden PRIDe Trial - Baden Prevention and Reduction of Incidence of Postoperative Delirium Trial[NCT02433041] | Phase 4 | 200 participants (Actual) | Interventional | 2013-07-31 | Completed | ||
| El DORADO STUDY (Evaluation of Delivery of Oxygen on Renal, Arrhythmia and Delirium Outcomes Study)[NCT04895384] | 600 participants (Anticipated) | Observational | 2021-07-27 | Recruiting | |||
| Preventing Post-Operative Delirium in Pneumonectomy, Esophagectomy and Thoracotomy Patients[NCT02213900] | Phase 4 | 135 participants (Actual) | Interventional | 2013-09-30 | Completed | ||
| Delirium: Is Prophylactic Drug Therapy Useful in High Risk Patients as Defined by the Delirium Risk Prediction Model?[NCT03199950] | Phase 4 | 1,366 participants (Anticipated) | Interventional | 2017-06-23 | Recruiting | ||
| Virtual Reality Stimulation to Relax and Reduce the Incidence of Delirium[NCT04498585] | 920 participants (Anticipated) | Interventional | 2021-04-14 | Suspended (stopped due to Decreased resources due to COVID-19) | |||
| Effect of Regional Anaesthesia and General Anaesthesia on Postoperative Delirium in Elderly Patients Undergoing Hip Fracture Surgery: a Multicenter Randomized Controlled Trial.[NCT02213380] | 950 participants (Actual) | Interventional | 2014-09-30 | Completed | |||
| Usefulness of Bright Light Therapy in the Prevention of Delirium in Patients Undergoing Hematopoietic Stem Cell Transplant (HSCT)[NCT01700816] | 40 participants (Actual) | Interventional | 2012-10-31 | Terminated (stopped due to Low incidence of delirium.) | |||
| Delirium in the ICU: a Prospective, Randomized, Trial of Placebo vs. Haloperidol vs. Ziprasidone[NCT00096863] | Phase 2 | 102 participants (Actual) | Interventional | 2004-12-31 | Completed | ||
| Southern Medical University Clinical Research Project Initiative：Efficacy and Safety of a Multicomponent Physical Therapy Program in Mechanically Ventilated Patient With Sepsis[NCT03406494] | 800 participants (Anticipated) | Interventional | 2018-03-31 | Not yet recruiting | |||
| Impact of Dexmedetomidine Combined With Ropivacaine for Postoperative Continuous Femoral Nerve Block on Postoperative Delirium and Long-term Oucomes in Elderly Patients After Single Knee Arthroplasty[NCT03629483] | Phase 4 | 736 participants (Anticipated) | Interventional | 2018-12-10 | Suspended (stopped due to Trial stopped by the sponsor because of no funding.) | ||
| Dynamic Light Application to Prevent ICU Acquired Delirium[NCT01274819] | 1,000 participants (Actual) | Interventional | 2011-07-31 | Completed | |||
| Impact of Dexmedetomidine Supplemented Intravenous Analgesia on Postoperative Delirium and Long-term Outcomes in Elderly After Orthopedic Surgery: A Multicenter, Double-blinded, Randomized Controlled Trial[NCT03629262] | Phase 4 | 712 participants (Actual) | Interventional | 2018-10-28 | Active, not recruiting | ||
| Impact of Dexmedetomidine Supplemented Analgesia on Delirium and Long-term Outcomes in Elderly After Hip Fracture Surgery: A Multicenter, Double-blinded, Randomized Controlled Trial[NCT04955249] | Phase 4 | 1,440 participants (Anticipated) | Interventional | 2021-11-18 | Recruiting | ||
| Risk Assessment for Postoperative Delirium: Derivation of a Self-Administered Tablet Computer-based Clinical Screening Tool[NCT02377115] | 54 participants (Actual) | Interventional | 2015-03-31 | Completed | |||
| Cukurova University Faculty of Medicine[NCT02360982] | 120 participants (Actual) | Observational | 2012-03-31 | Completed | |||
| Evaluation of the Standardised Nurse-led Approach for Risk Screening and Decrease of Alcohol Withdrawal Among Adult Inpatients With Alcohol Dependence in an Ear, Nose, Throat and Jaw Surgery Department[NCT02782156] | 89 participants (Actual) | Observational | 2014-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Test the efficacy of low dose haloperidol in reducing the number of days with delirium among patients who are status post esophagectomy, pneumonectomy or thoracotomy compared to placebo. (NCT02213900)
Timeframe: Up to 30 days
| Intervention | Days with Delirium (Mean) |
|---|---|
| Haloperidol | 0.3 |
| Placebo | 0.5 |
Test the efficacy of low dose haloperidol in reducing delirium incidence among patients who are status post esophagectomy, pneumonectomy or thoracotomy compared to placebo. (NCT02213900)
Timeframe: Up to 30 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Haloperidol | 15 |
| Placebo | 19 |
Test the efficacy of low dose haloperidol in reducing cognitive impairment at post-operative follow-up among patients who are status post esophagectomy, pneumonectomy or thoracotomy compared to placebo. Cognitive status is assessed using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). The RBANS measures attention, language, visuospatial/constructional abilities, and memory. It is made up of 12 subtests. The subtests produce 5 index scores and a total scale score. All the subtest scores are summed to calculate a Total Index score. The Total Index score is presented. The Total Index score scale is from 0-100 with higher scores indicating less cognitive impairment. (NCT02213900)
Timeframe: Up to 3 months after hospital discharge on average.
| Intervention | Units on a scale (Mean) | |
|---|---|---|
| Baseline RBANS Total Score | 3 Month RBANS Total Score | |
| Haloperidol | 31.7 | 31.8 |
| Placebo | 30.1 | 22.7 |
Test the efficacy of low dose haloperidol in reducing ICU and hospital length of stay among patients who are status post esophagectomy or pneumonectomy compared to placebo. (NCT02213900)
Timeframe: Date of hospital admission through date of hospital discharge, up to 3 weeks on average.
| Intervention | Days (Mean) | |
|---|---|---|
| ICU Length of Stay | Overall Length of Stay | |
| Haloperidol | 2.5 | 9.3 |
| Placebo | 2.8 | 10.2 |
Mortality within 30 days post operation (NCT02213380)
Timeframe: 30 days after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Group RA | 8 |
| Group GA | 4 |
The worst pain score within 7 days post-operation in both groups. The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between no pain(0 point) to worst pain (100 points). (NCT02213380)
Timeframe: In 7days post operation
| Intervention | score on a scale (Median) |
|---|---|
| Group RA | 0 |
| Group GA | 0 |
Costs of anesthetic procedure only (NCT02213380)
Timeframe: 1 day after operation
| Intervention | dollars (Median) |
|---|---|
| Group RA | 159 |
| Group GA | 268 |
Length of hospital stay are measured from the anesthesia starting day to the discharge day (NCT02213380)
Timeframe: till the day of discharge from hospital, an average of 7 days
| Intervention | days (Median) |
|---|---|
| Group RA | 7 |
| Group GA | 7 |
Post-operative delirium diagnosed with Confusion Assessment Method (NCT02213380)
Timeframe: in 7 days post operation
| Intervention | Participants (Count of Participants) |
|---|---|
| Group RA | 29 |
| Group GA | 24 |
The worst severity scores of delirium was diagnosed with the DRS-R-98 within 7 days (NCT02213380)
Timeframe: within first 7days post operation
| Intervention | score on a scale (Mean) |
|---|---|
| Group RA | 23.48 |
| Group GA | 24.22 |
Entire expenditure in-hospital (NCT02213380)
Timeframe: till the day of discharge
| Intervention | dollars (Median) |
|---|---|
| Group RA | 5582 |
| Group GA | 5908 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | volume percentage (vol%) of red blood ce (Median) |
|---|---|
| Bright Light Therapy | 28.20 |
| Sham Light | 26.70 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | g/dl (Median) |
|---|---|
| Bright Light Therapy | 9.70 |
| Sham Light | 9.55 |
(NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | days (Median) |
|---|---|
| Bright Light Therapy | 18 |
| Sham Light | 18.5 |
Monday, Wednesday, and Friday assessments will begin after beginning light therapy and include the Delirium Rating Scale-Revised-98 (DRS-98)and Memorial Delirium Assessment Scale (MDAS) (NCT01700816)
Timeframe: From hospital admission until the date of first documented delirium, assessed up to 28 days post-transplant
| Intervention | Participants (Count of Participants) |
|---|---|
| Bright Light Therapy | 1 |
| Sham Light | 0 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | thousand cells/uL (Median) |
|---|---|
| Bright Light Therapy | 39 |
| Sham Light | 33.5 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | M/uL (Median) |
|---|---|
| Bright Light Therapy | 3.21 |
| Sham Light | 2.93 |
"Monday, Wednesday, and Friday assessments of the Memorial Delirium Assessment Scale (MDAS); Patients will receive assessments after beginning light therapy until day 28 post-transplant or discharge, whichever comes first.~10 item scale Items are rated on a four-point scale from 0 (none) to 3 (severe) depending on the level of impairment, rendering a maximum possible score of 30.~A score of 13 has been recommended as a cut-off for establishing the diagnosis of delirium" (NCT01700816)
Timeframe: From first documented episode of delirium until discharge from the hospital, assessed up to 28 days post-transplant
| Intervention | units on a scale (Number) |
|---|---|
| Bright Light Therapy | 18 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | K/uL (Median) |
|---|---|
| Bright Light Therapy | 2.30 |
| Sham Light | 4.75 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | mg/dl (Median) | |
|---|---|---|
| Serum Creatinine | Blood Urea Nitrogen (BUN) | |
| Bright Light Therapy | 0.66 | 9 |
| Sham Light | 0.75 | 8.5 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT (Hematopoietic Stem Cell Transplantation). (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | mmol/L (Median) | |||
|---|---|---|---|---|
| Sodium (Na) | Potassium (K) | Chloride (Cl) | Carbon Dioxide (CO2) | |
| Bright Light Therapy | 139 | 3.6 | 105 | 24.9 |
| Sham Light | 138.0 | 3.80 | 103.0 | 25.10 |
6 reviews available for haloperidol and Complication, Postoperative
| Article | Year |
|---|---|
Comparative effectiveness of pharmacological interventions to prevent postoperative delirium: a network meta-analysis.
Topics: Adult; Antipsychotic Agents; Bayes Theorem; Delirium; Haloperidol; Humans; Network Meta-Analysis; Ph | 2021 |
Update in perioperative medicine: practice changing evidence published in 2016.
Topics: Amines; Analgesics; Anticoagulants; Antipsychotic Agents; Arthritis, Rheumatoid; Blood Transfusion; | 2017 |
Effects of Haloperidol on Delirium in Adult Patients: A Systematic Review and Meta-Analysis.
Topics: Adult; Antipsychotic Agents; Delirium; Female; Haloperidol; Humans; Male; Postoperative Complication | 2018 |
Pharmacologic prevention and treatment of delirium in intensive care patients: A systematic review.
Topics: Antipsychotic Agents; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Haloperidol; Human | 2015 |
Adjunctive haloperidol prophylaxis reduces postoperative delirium severity and duration in at-risk elderly patients.
Topics: Aged; Antipsychotic Agents; Chemotherapy, Adjuvant; Delirium; Haloperidol; Humans; Male; Postoperati | 2008 |
Adjunctive haloperidol prophylaxis reduces postoperative delirium severity and duration in at-risk elderly patients.
Topics: Aged; Antipsychotic Agents; Chemotherapy, Adjuvant; Delirium; Haloperidol; Humans; Male; Postoperati | 2008 |
Adjunctive haloperidol prophylaxis reduces postoperative delirium severity and duration in at-risk elderly patients.
Topics: Aged; Antipsychotic Agents; Chemotherapy, Adjuvant; Delirium; Haloperidol; Humans; Male; Postoperati | 2008 |
Adjunctive haloperidol prophylaxis reduces postoperative delirium severity and duration in at-risk elderly patients.
Topics: Aged; Antipsychotic Agents; Chemotherapy, Adjuvant; Delirium; Haloperidol; Humans; Male; Postoperati | 2008 |
[Delirium after open-heart surgery. Prevalence, risk factors and therapeutic approach].
Topics: Cardiac Surgical Procedures; Delirium; Haloperidol; Humans; Intraoperative Period; Postoperative Com | 1994 |
18 trials available for haloperidol and Complication, Postoperative
| Article | Year |
|---|---|
Baden Prevention and Reduction of Incidence of Postoperative Delirium Trial (PRIDe): a phase IV multicenter, randomized, placebo-controlled, double-blind clinical trial of ketamine versus haloperidol for prevention of postoperative delirium.
Topics: Anesthetics, Dissociative; Antipsychotic Agents; Clinical Trials, Phase IV as Topic; Delirium; Doubl | 2018 |
Preventing Postoperative Delirium After Major Noncardiac Thoracic Surgery-A Randomized Clinical Trial.
Topics: Administration, Intravenous; Antipsychotic Agents; Delirium; Double-Blind Method; Esophagectomy; Fem | 2018 |
Morphine is a reasonable alternative to haloperidol in the treatment of postoperative hyperactive-type delirium after cardiac surgery.
Topics: Aged; Antipsychotic Agents; Cardiac Surgical Procedures; Delirium; Female; Haloperidol; Humans; Male | 2013 |
Haloperidol prophylaxis does not prevent postoperative delirium in elderly patients: a randomized, open-label prospective trial.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Digestive System Surgical Procedures; Elect | 2014 |
Haloperidol prophylaxis for preventing aggravation of postoperative delirium in elderly patients: a randomized, open-label prospective trial.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Elective Surgical Procedures; Female; Halop | 2017 |
Translating Delirium Prevention Strategies for Elderly Adults with Hip Fracture into Routine Clinical Care: A Pragmatic Clinical Trial.
Topics: Aged; Aged, 80 and over; Analgesics; Anti-Dyskinesia Agents; Dehydration; Delirium; Female; Haloperi | 2017 |
Long-term cognitive outcome of delirium in elderly hip surgery patients. A prospective matched controlled study over two and a half years.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Arthroplasty, Replacement, Hip; Case-Control Studies; | 2008 |
Feasibility, efficacy, and safety of antipsychotics for intensive care unit delirium: the MIND randomized, placebo-controlled trial.
Topics: Adult; Aged; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; Humans; Inten | 2010 |
Haloperidol prophylaxis decreases delirium incidence in elderly patients after noncardiac surgery: a randomized controlled trial*.
Topics: Aged; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; Humans; Incidence; M | 2012 |
Ondasetron versus haloperidol for the treatment of postcardiotomy delirium: a prospective, randomized, double-blinded study.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Cardiac Surgical Procedures; Delirium; Double-Blind M | 2012 |
A reorientation strategy for reducing delirium in the critically ill. Results of an interventional study.
Topics: Acoustic Stimulation; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Critical Care; | 2012 |
Effect of preoperative discontinuation of antipsychotics in schizophrenic patients on outcome during and after anaesthesia.
Topics: Adult; Analysis of Variance; Anesthesia; Anesthesia Recovery Period; Anesthetics, Intravenous; Antip | 2004 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Early symptoms in the prodromal phase of delirium: a prospective cohort study in elderly patients undergoing hip surgery.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; APACHE; Cohort Studies; Delirium; Double-Blind Method | 2007 |
Prophylaxis of alcohol withdrawal syndrome in alcohol-dependent patients admitted to the intensive care unit after tumour resection.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Chlormethiazole; Clonidine; Critical Care | 1995 |
The use of haloperidol for treatment of postoperative nausea and vomiting--a double-blind placebo-controlled trial.
Topics: Abdomen; Adolescent; Adult; Aged; Anesthesia, Inhalation; Anesthetics; Clinical Trials as Topic; Col | 1975 |
[Alcohol withdrawal syndrome in the postoperative phase--therapy or prevention?].
Topics: Alcohol Withdrawal Delirium; Chlormethiazole; Critical Care; Drug Therapy, Combination; Haloperidol; | 1990 |
A double-blind cross-over clinical valuation of metoclopramide and a combination of haloperidol and isopropamide iodide in gastroenterology.
Topics: Adolescent; Adult; Antiemetics; Clinical Trials as Topic; Colonic Diseases; Constipation; Crohn Dise | 1969 |
37 other studies available for haloperidol and Complication, Postoperative
| Article | Year |
|---|---|
A case of hyperventilation leading to apnea and desaturation in PACU.
Topics: Adolescent; Anesthesia Recovery Period; Anesthesia, General; Apnea; Female; Haloperidol; Humans; Hyp | 2019 |
The influence of oxygen delivery during cardiopulmonary bypass on the incidence of delirium in CABG patients; a retrospective study.
Topics: Aged; Cardiopulmonary Bypass; Coronary Artery Bypass; Delirium; Female; Haloperidol; Humans; Inciden | 2018 |
[A Multicenter Questionnaire Survey of Postoperative Delirium -National Hospital Organization, Surgery and Anesthesia Network Group-].
Topics: Aged; Anesthesia; Delirium; Female; Haloperidol; Humans; Incidence; Postoperative Complications; Pos | 2016 |
[Delirium prevention and treatment in elderly hip fracture].
Topics: Aged; Anesthesia, Epidural; Anesthesia, General; Benzodiazepines; Cognition Disorders; Combined Moda | 2014 |
[Perioperative management of off-pump CABG for a 93-year-old man].
Topics: Aged, 80 and over; Anesthesia; Brain; Cerebrovascular Circulation; Consciousness Monitors; Coronary | 2014 |
Use of Dexmedetomidine in Liver Transplant Recipients With Postoperative Agitated Delirium.
Topics: Adult; Aged; Antipsychotic Agents; Delirium; Dexmedetomidine; Female; Haloperidol; Humans; Hypnotics | 2016 |
Delirium associated with olanzapine use in the elderly.
Topics: Aged; Antipsychotic Agents; Aortic Aneurysm; Benzodiazepines; Delirium; Haloperidol; Humans; Male; O | 2017 |
Postoperative delirium.
Topics: Antipsychotic Agents; Delirium; Diagnosis, Differential; Electrocardiography; Electroencephalography | 2008 |
New-onset psychosis after temporal lobectomy.
Topics: Antipsychotic Agents; Electroencephalography; Epilepsy, Temporal Lobe; Haloperidol; Humans; Magnetic | 2008 |
[Hyperventilation syndrome before induction of and after awakening from general anesthesia].
Topics: Anesthesia, Epidural; Anesthesia, General; Antipsychotic Agents; Anxiety; Arthroplasty, Replacement, | 2009 |
Free your MIND and the rest will follow: decoding delirium in the intensive care unit.
Topics: Antipsychotic Agents; Delirium; Haloperidol; Humans; Intensive Care Units; Piperazines; Postoperativ | 2010 |
Relief by electroconvulsive therapy for postsurgical delirium in malignant catatonia.
Topics: Antipsychotic Agents; Cardiac Surgical Procedures; Catatonia; Coronary Artery Bypass; Delirium; Elec | 2010 |
Mortality associated with delirium after hip-surgery: a 2-year follow-up study.
Topics: Aged; Antipsychotic Agents; Delirium; Female; Follow-Up Studies; Haloperidol; Hip; Hospitalization; | 2011 |
Anesthesia and postoperative delirium in older adults undergoing hip surgery.
Topics: Aged; Anesthesia, Conduction; Anesthesia, General; Cognition Disorders; Delirium; Female; Haloperido | 2011 |
Delirium, sigma-1 receptors, dopamine, and glutamate: how does haloperidol keep the genie in the bottle?*.
Topics: Antipsychotic Agents; Delirium; Female; Haloperidol; Humans; Male; Postoperative Complications | 2012 |
The largest ever trial demonstrating effectiveness of intensive care unit delirium prophylaxis--we must know more!
Topics: Antipsychotic Agents; Delirium; Female; Haloperidol; Humans; Male; Postoperative Complications | 2012 |
Neuroleptic malignant syndrome: uncommon postoperative diagnostic dilemma.
Topics: Aged; Bromocriptine; Coronary Artery Bypass; Coronary Artery Disease; Dementia; Diagnosis, Different | 2002 |
Impact of an alcohol withdrawal syndrome practice guideline on surgical patient outcomes.
Topics: Adolescent; Adult; Aged; Alcohol-Related Disorders; Clonidine; Ethanol; Female; Haloperidol; Humans; | 2003 |
Intravenous ziprasidone for treatment of delirium in the intensive care unit.
Topics: Antipsychotic Agents; Bone Transplantation; Critical Care; Delirium; Haloperidol; Humans; Male; Midd | 2004 |
Auditory hallucinations after right temporal gyri resection.
Topics: Adult; Affect; Anticonvulsants; Antipsychotic Agents; Brain Injuries; Carbamazepine; Electroencephal | 2005 |
Perioperative haloperidol usage for delirium management.
Topics: Aged; Antipsychotic Agents; Delirium; Haloperidol; Humans; Length of Stay; Perioperative Care; Posto | 2006 |
Perioperative haloperidol to prevent postoperative delirium.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dose-Response Relationship, Drug; Drug Th | 2006 |
Issues in reimbursement for consultation-liaison psychiatry.
Topics: Coronary Artery Bypass; Delirium; Haloperidol; Humans; Insurance, Health, Reimbursement; Male; Middl | 1984 |
Complex management of postcardiotomy delirium.
Topics: Cardiac Surgical Procedures; Delirium; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; | 1983 |
Migraine and surgery. Avoidance of trigger mechanisms.
Topics: Anesthesia, General; Diazepam; Female; Glucose; Haloperidol; Humans; Intraoperative Period; Male; Mi | 1980 |
The duration of delirium in medical and postoperative patients referred for psychiatric consultation.
Topics: Aged; Delirium; Dementia; Female; Haloperidol; Humans; Length of Stay; Male; Middle Aged; Patient Ca | 1997 |
Choreoathetosis after cardiac surgery with hypothermia and extracorporeal circulation.
Topics: Adolescent; Anti-Dyskinesia Agents; Athetosis; Benzodiazepines; Cardiac Surgical Procedures; Chorea; | 1998 |
Torsades de pointes secondary to intravenous haloperidol after coronary bypass grafting surgery.
Topics: Anti-Dyskinesia Agents; Antipsychotic Agents; Coronary Artery Bypass; Critical Care; Delirium; Elect | 2000 |
Comparison of droperidol, haloperidol and prochlorperazine as postoperative anti-emetics.
Topics: Droperidol; Haloperidol; Humans; Postoperative Complications; Prochlorperazine; Sodium Chloride; Vom | 1979 |
[Malignant neuroleptic syndrome: complete anticoagulant treatment or not?].
Topics: Adult; Anticoagulants; Biperiden; Depressive Disorder; Drug Therapy, Combination; Haloperidol; Human | 1992 |
Spontaneous bacterial peritonitis in a healthy adult male.
Topics: Adult; Alcohol Withdrawal Delirium; Diazepam; Haloperidol; Humans; Male; Peritonitis; Postoperative | 1990 |
The neuroleptic malignant syndrome.
Topics: Adult; Female; Haloperidol; Humans; Metoclopramide; Neuroleptic Malignant Syndrome; Postoperative Co | 1990 |
Treatment of acute nonspecific delirium with i.v. haloperidol in surgical intensive care patients.
Topics: Acute Disease; Aged; Delirium; Female; Haloperidol; Humans; Infusions, Intravenous; Male; Postoperat | 1989 |
Neuroleptic malignant syndrome.
Topics: Adult; Female; Haloperidol; Humans; Hysterectomy; Hysterectomy, Vaginal; Neuroleptic Malignant Syndr | 1986 |
Presenile dementia: further experience with an anticoagulant-psychotherapy regimen.
Topics: Adult; Aged; Anticoagulants; Anxiety; Atrophy; Brain Diseases; Dementia; Dicumarol; Fear; Female; Ha | 1974 |
Right Ventricular Outflow Tract Replacement With Xenografts in Ross Patients Older Than 60 Years.
Topics: Age Factors; Aged; Animals; Aortic Valve; Autografts; Bioprosthesis; Calcinosis; Cattle; Endocarditi | 2016 |
Withstand pressure of a simple fibrin glue sealant: experimental study of mimicked sellar reconstruction in extended transsphenoidal surgery.
Topics: Cerebrospinal Fluid Pressure; Cranial Fossa, Anterior; Craniotomy; Epoxy Resins; Fibrin Tissue Adhes | 2010 |