haloperidol has been researched along with Cocaine Abuse in 14 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-one subjects with cocaine dependence and schizophrenia were randomized to olanzapine or haloperidol, underwent a cue-exposure procedure, and completed psychiatric and substance abuse ratings." | 9.12 | The efficacy of olanzapine for decreasing cue-elicited craving in individuals with schizophrenia and cocaine dependence: a preliminary report. ( Kaune, M; Losonczy, MF; Smelson, DA; Steinberg, ML; Williams, J; Ziedonis, D, 2006) |
| "Comorbid cocaine abuse adversely affects clinical outcomes in schizophrenia." | 6.71 | Cocaine abuse in schizophrenic patients treated with olanzapine versus haloperidol. ( Campbell, EC; Caroff, SN; Cornish, J; Kondrich, J; Mann, SC; O'Brien, C; Sayers, SL, 2005) |
| "Thirty-one subjects with cocaine dependence and schizophrenia were randomized to olanzapine or haloperidol, underwent a cue-exposure procedure, and completed psychiatric and substance abuse ratings." | 5.12 | The efficacy of olanzapine for decreasing cue-elicited craving in individuals with schizophrenia and cocaine dependence: a preliminary report. ( Kaune, M; Losonczy, MF; Smelson, DA; Steinberg, ML; Williams, J; Ziedonis, D, 2006) |
| "The neuropharmacological profile of the atypical antipsychotic, olanzapine, is consistent with a potentially useful medication for cocaine abuse." | 3.73 | Olanzapine-induced suppression of cocaine self-administration in rhesus monkeys. ( Howell, LL; Kimmel, HL; Lindsey, KP; Wilcox, KM, 2006) |
| "Comorbid cocaine abuse adversely affects clinical outcomes in schizophrenia." | 2.71 | Cocaine abuse in schizophrenic patients treated with olanzapine versus haloperidol. ( Campbell, EC; Caroff, SN; Cornish, J; Kondrich, J; Mann, SC; O'Brien, C; Sayers, SL, 2005) |
| "Cocaine dependence is a public health problem characterised by recidivism and a host of medical and psychosocial complications." | 2.53 | Antipsychotic medications for cocaine dependence. ( Amato, L; Indave, BI; Minozzi, S; Pani, PP, 2016) |
| "Risperidone was found to be superior to placebo in diminishing the number of dropouts, four studies, 178 participants, Relative Risk (RR) 0." | 2.44 | Antipsychotic medications for cocaine dependence. ( Amato, L; Davoli, M; Minozzi, S; Pani, PP, 2007) |
| "Cariprazine (RGH-188) is a D₃-preferring dopamine D₃/D₂ receptor partial agonist antipsychotic candidate for the treatment of schizophrenia and bipolar mania." | 1.39 | Cariprazine (RGH-188), a D₃-preferring dopamine D₃/D₂ receptor partial agonist antipsychotic candidate demonstrates anti-abuse potential in rats. ( Gyertyán, I; Kiss, B; Román, V; Sághy, K; Szombathelyi, Z, 2013) |
| "treated with haloperidol (1." | 1.35 | Haloperidol (but not ziprasidone) withdrawal potentiates sensitization to the hyperlocomotor effect of cocaine in mice. ( Alvarez, Jdo N; Carvalho, Rde C; Frussa-Filho, R; Fukushiro, DF; Ribeiro, LT; Ricardo, VP, 2008) |
| "Treatment of schizophrenia is often complicated by substance abuse." | 1.30 | Alcohol dependence and hospitalization in schizophrenia. ( Arana, GW; Gerding, LB; Labbate, LA; Measom, MO; Santos, AB, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 8 (57.14) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mésangeau, C | 1 |
| Narayanan, S | 1 |
| Green, AM | 1 |
| Shaikh, J | 1 |
| Kaushal, N | 1 |
| Viard, E | 1 |
| Xu, YT | 1 |
| Fishback, JA | 1 |
| Poupaert, JH | 1 |
| Matsumoto, RR | 1 |
| McCurdy, CR | 1 |
| Marinho, EA | 1 |
| Oliveira-Lima, AJ | 1 |
| Wuo-Silva, R | 1 |
| Santos, R | 1 |
| Baldaia, MA | 1 |
| Hollais, AW | 1 |
| Longo, BM | 1 |
| Berro, LF | 1 |
| Frussa-Filho, R | 2 |
| Indave, BI | 1 |
| Minozzi, S | 2 |
| Pani, PP | 2 |
| Amato, L | 2 |
| Fukushiro, DF | 1 |
| Carvalho, Rde C | 1 |
| Ricardo, VP | 1 |
| Alvarez, Jdo N | 1 |
| Ribeiro, LT | 1 |
| Oleson, EB | 1 |
| Richardson, JM | 1 |
| Roberts, DC | 1 |
| Román, V | 1 |
| Gyertyán, I | 2 |
| Sághy, K | 1 |
| Kiss, B | 1 |
| Szombathelyi, Z | 1 |
| Vorel, SR | 1 |
| Ashby, CR | 1 |
| Paul, M | 1 |
| Liu, X | 1 |
| Hayes, R | 1 |
| Hagan, JJ | 1 |
| Middlemiss, DN | 1 |
| Stemp, G | 1 |
| Gardner, EL | 1 |
| Sayers, SL | 1 |
| Campbell, EC | 1 |
| Kondrich, J | 1 |
| Mann, SC | 1 |
| Cornish, J | 1 |
| O'Brien, C | 1 |
| Caroff, SN | 1 |
| Gál, K | 1 |
| Howell, LL | 1 |
| Wilcox, KM | 1 |
| Lindsey, KP | 1 |
| Kimmel, HL | 1 |
| Smelson, DA | 1 |
| Ziedonis, D | 1 |
| Williams, J | 2 |
| Losonczy, MF | 1 |
| Steinberg, ML | 1 |
| Kaune, M | 1 |
| Davoli, M | 1 |
| Garver, DL | 1 |
| Nair, TR | 1 |
| Christensen, JD | 1 |
| Holcomb, J | 1 |
| Ramberg, J | 1 |
| Kingsbury, S | 1 |
| Gerding, LB | 1 |
| Labbate, LA | 1 |
| Measom, MO | 1 |
| Santos, AB | 1 |
| Arana, GW | 1 |
2 reviews available for haloperidol and Cocaine Abuse
| Article | Year |
|---|---|
Antipsychotic medications for cocaine dependence.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Cocaine-Related Disorders; Haloperidol; Humans; | 2016 |
Antipsychotic medications for cocaine dependence.
Topics: Antipsychotic Agents; Benzodiazepines; Cocaine-Related Disorders; Haloperidol; Humans; Olanzapine; R | 2007 |
3 trials available for haloperidol and Cocaine Abuse
| Article | Year |
|---|---|
Cocaine abuse in schizophrenic patients treated with olanzapine versus haloperidol.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Behavior, Addictive; Benzodiazepines; Cocaine-Related | 2005 |
The efficacy of olanzapine for decreasing cue-elicited craving in individuals with schizophrenia and cocaine dependence: a preliminary report.
Topics: Adult; Antipsychotic Agents; Behavior, Addictive; Benzodiazepines; Cocaine-Related Disorders; Cues; | 2006 |
Atrophic and static (neurodevelopmental) schizophrenic psychoses: premorbid functioning, symptoms and neuroleptic response.
Topics: Adult; Aging; Alcohol Drinking; Algorithms; Antipsychotic Agents; Atrophy; Brain; Cerebral Ventricle | 1999 |
9 other studies available for haloperidol and Cocaine Abuse
| Article | Year |
|---|---|
Conversion of a highly selective sigma-1 receptor-ligand to sigma-2 receptor preferring ligands with anticocaine activity.
Topics: Animals; Anticonvulsants; Brain; Cocaine; Cocaine-Related Disorders; In Vitro Techniques; Ligands; M | 2008 |
Selective action of an atypical neuroleptic on the mechanisms related to the development of cocaine addiction: a pre-clinical behavioural study.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Central Nervous System Sensitization; | 2014 |
Haloperidol (but not ziprasidone) withdrawal potentiates sensitization to the hyperlocomotor effect of cocaine in mice.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Haloperidol; Hu | 2008 |
A novel IV cocaine self-administration procedure in rats: differential effects of dopamine, serotonin, and GABA drug pre-treatments on cocaine consumption and maximal price paid.
Topics: Analysis of Variance; Animals; Appetitive Behavior; Baclofen; Behavior, Animal; Central Nervous Syst | 2011 |
Cariprazine (RGH-188), a D₃-preferring dopamine D₃/D₂ receptor partial agonist antipsychotic candidate demonstrates anti-abuse potential in rats.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Benzoxazoles; Cocaine-Related Disorders; Dopamine Agoni | 2013 |
Dopamine D3 receptor antagonism inhibits cocaine-seeking and cocaine-enhanced brain reward in rats.
Topics: Animals; Behavior, Animal; Brain; Catalepsy; Cocaine; Cocaine-Related Disorders; Conditioning, Opera | 2002 |
Dopamine D3 as well as D2 receptor ligands attenuate the cue-induced cocaine-seeking in a relapse model in rats.
Topics: Animals; Brain; Cocaine-Related Disorders; Cues; Dopamine Agonists; Dopamine Antagonists; Dose-Respo | 2006 |
Olanzapine-induced suppression of cocaine self-administration in rhesus monkeys.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Cocaine-Related Disorders; Data Interpretation, Stat | 2006 |
Alcohol dependence and hospitalization in schizophrenia.
Topics: Adult; Alcoholism; Antipsychotic Agents; Cocaine-Related Disorders; Comorbidity; Female; Fluphenazin | 1999 |