haloperidol has been researched along with Choriocarcinoma in 3 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The expression and ligand binding characteristics of sigma-receptors in human placental syncytiotrophoblast and choriocarcinoma cells were investigated using haloperidol as a ligand." | 7.69 | Cocaine-sensitive sigma-receptor and its interaction with steroid hormones in the human placental syncytiotrophoblast and in choriocarcinoma cells. ( Ganapathy, V; Leibach, FH; Mahesh, VB; Ramamoorthy, JD; Ramamoorthy, S, 1995) |
| "Augmentation strategy in the treatment of schizophrenia with the NMDA receptor co-agonist glycine has demonstrated significant improvement in patient symptoms." | 3.72 | Effects of typical and atypical antipsychotics on human glycine transporters. ( Conn, PJ; Mallorga, PJ; Pettibone, DJ; Sur, C; Williams, JB, 2004) |
| "The expression and ligand binding characteristics of sigma-receptors in human placental syncytiotrophoblast and choriocarcinoma cells were investigated using haloperidol as a ligand." | 3.69 | Cocaine-sensitive sigma-receptor and its interaction with steroid hormones in the human placental syncytiotrophoblast and in choriocarcinoma cells. ( Ganapathy, V; Leibach, FH; Mahesh, VB; Ramamoorthy, JD; Ramamoorthy, S, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Williams, JB | 1 |
| Mallorga, PJ | 1 |
| Conn, PJ | 1 |
| Pettibone, DJ | 1 |
| Sur, C | 1 |
| Ramamoorthy, JD | 1 |
| Ramamoorthy, S | 1 |
| Mahesh, VB | 1 |
| Leibach, FH | 2 |
| Ganapathy, V | 2 |
| Seth, P | 1 |
| Fei, YJ | 1 |
| Li, HW | 1 |
| Huang, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Glycine Transport Inhibition on Brain Glycine Concentration[NCT00538070] | 68 participants (Actual) | Interventional | 2007-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for haloperidol and Choriocarcinoma
| Article | Year |
|---|---|
Effects of typical and atypical antipsychotics on human glycine transporters.
Topics: Amino Acid Transport Systems, Neutral; Animals; Antipsychotic Agents; Benzodiazepines; Brain; Chlori | 2004 |
Cocaine-sensitive sigma-receptor and its interaction with steroid hormones in the human placental syncytiotrophoblast and in choriocarcinoma cells.
Topics: Choriocarcinoma; Cocaine; Female; Giant Cells; Gonadal Steroid Hormones; Haloperidol; Humans; Ligand | 1995 |
Cloning and functional characterization of a sigma receptor from rat brain.
Topics: Amino Acid Sequence; Animals; Anticonvulsants; Antidepressive Agents; Base Sequence; Binding, Compet | 1998 |