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haloperidol and Cerebral Ischemia

haloperidol has been researched along with Cerebral Ischemia in 19 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Research Excerpts

ExcerptRelevanceReference
" Strong concerns have been raised about whether the risk of ischemic stroke differs between risperidone and haloperidol."7.81A comparison of risperidone and haloperidol for the risk of ischemic stroke in the elderly: a propensity score-matched cohort analysis. ( Choi, NK; Lee, J; Lee, SH; Park, BJ; Park, MJ; Shin, JY, 2015)
" Strong concerns have been raised about whether the risk of ischemic stroke differs between risperidone and haloperidol."3.81A comparison of risperidone and haloperidol for the risk of ischemic stroke in the elderly: a propensity score-matched cohort analysis. ( Choi, NK; Lee, J; Lee, SH; Park, BJ; Park, MJ; Shin, JY, 2015)
"Global cerebral ischemia/reperfusion (GCI/R) injury in swiss albino mice was induced by occluding the common carotid arteries for 17 min, followed by 24 h reperfusion."1.56Possible involvement of D2/D3 receptor activation in ischemic preconditioning mediated protection of the brain. ( Kulkarni, GT; Sharma, B; Sharma, P, 2020)
"Haloperidol is an effective antipsychotic agent, but it causes Parkinsonian-like extrapyramidal symptoms in the majority of treated subjects."1.43A Pharmacogenetic Discovery: Cystamine Protects Against Haloperidol-Induced Toxicity and Ischemic Brain Injury. ( Clark, JD; Dill, DL; Giffard, R; Nishimura, T; Nishimura, Y; Peltz, G; Sahbaie, P; Wu, M; Xiong, X; Xu, D; Xu, LJ; Zhang, H; Zheng, M, 2016)
" Piglets subjected to hypoxia followed by asphyxic cardiac arrest were treated with saline or two dosing regimens of PPBP after resuscitation."1.36Sigma receptor ligand 4-phenyl-1-(4-phenylbutyl)-piperidine modulates neuronal nitric oxide synthase/postsynaptic density-95 coupling mechanisms and protects against neonatal ischemic degeneration of striatal neurons. ( Carter, EL; Koehler, RC; Martin, LJ; Torbey, MT; Yang, ZJ, 2010)
"Hemiballismus is characterized by the abrupt onset of violent proximal flinging movements, affecting the limbs, neck and trunk on one side of the body."1.32Hemiballismus following general anesthesia. A case report. ( Buraczyńska, K; Pilarczyk, M; Sagan, M; Stelmasiak, Z; Tynecka, M, 2003)
"When haloperidol 2 mg/kg was administered i."1.31Dopaminergic neurotransmission triggers ischemia-induced hyperactivity in Mongolian gerbils. ( Araki, H; Futagami, K; Gomita, Y; Kawasaki, H; Yamamoto, T, 2001)
"Risperidone was well tolerated despite this adolescent's severe cardiac and pulmonary illnesses."1.29Use of risperidone in psychotic disorder following ischemic brain damage. ( DeMaso, DR; Steingard, RJ; Zimnitzky, BM, 1996)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.79)18.7374
1990's6 (31.58)18.2507
2000's5 (26.32)29.6817
2010's4 (21.05)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Sharma, P1
Kulkarni, GT1
Sharma, B1
Shin, JY1
Choi, NK1
Lee, J1
Park, MJ1
Lee, SH1
Park, BJ1
Zhang, H1
Zheng, M1
Wu, M1
Xu, D1
Nishimura, T1
Nishimura, Y1
Giffard, R1
Xiong, X1
Xu, LJ1
Clark, JD1
Sahbaie, P1
Dill, DL1
Peltz, G1
Rajput, SK1
Sharma, AK1
Meena, CL1
Pant, AB1
Jain, R1
Sharma, SS1
Yang, ZJ1
Carter, EL1
Torbey, MT1
Martin, LJ1
Koehler, RC2
Goyagi, T2
Bhardwaj, A4
Traystman, RJ3
Hurn, PD3
Kirsch, JR4
Pilarczyk, M1
Buraczyńska, K1
Sagan, M1
Tynecka, M1
Stelmasiak, Z1
Okajima, Y1
Nishi, K1
Busch, KT1
Schulz, H1
Wishart, TB1
Ijaz, S1
Shuaib, A1
Dragunow, M1
Young, D1
Hughes, P1
MacGibbon, G1
Lawlor, P1
Singleton, K1
Sirimanne, E1
Beilharz, E1
Gluckman, P1
Zimnitzky, BM1
DeMaso, DR1
Steingard, RJ1
Vila, N1
Chamorro, A1
O'Neill, MJ1
Hicks, CA1
Ward, MA1
Cardwell, GP1
Reymann, JM1
Allain, H1
Bentué-Ferrer, D1
Harukuni, I2
Crain, B1
London, ED2
Shaivitz, AB1
DeVries, AC1
Faraci, FM1
Goto, S1
Dawson, VL1
Yamamoto, T1
Araki, H1
Futagami, K1
Kawasaki, H1
Gomita, Y1
Ahlemeyer, B1
Krieglstein, J1

Other Studies

19 other studies available for haloperidol and Cerebral Ischemia

ArticleYear
Possible involvement of D2/D3 receptor activation in ischemic preconditioning mediated protection of the brain.
    Brain research, 2020, 12-01, Volume: 1748

    Topics: Animals; Brain Ischemia; Cytokines; Dopamine Antagonists; Haloperidol; Ischemic Preconditioning; Mal

2020
A comparison of risperidone and haloperidol for the risk of ischemic stroke in the elderly: a propensity score-matched cohort analysis.
    Journal of psychopharmacology (Oxford, England), 2015, Volume: 29, Issue:8

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Brain Ischemia; Cohort Studies; Female; Haloperidol;

2015
A Pharmacogenetic Discovery: Cystamine Protects Against Haloperidol-Induced Toxicity and Ischemic Brain Injury.
    Genetics, 2016, Volume: 203, Issue:1

    Topics: Amidohydrolases; Animals; Antipsychotic Agents; Brain Ischemia; Cell Adhesion Molecules; Cystamine;

2016
Effect of L-pGlu-(1-benzyl)-l-His-l-Pro-NH
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain Ischemia; Catalepsy; Cell Death; Diseas

2016
Sigma receptor ligand 4-phenyl-1-(4-phenylbutyl)-piperidine modulates neuronal nitric oxide synthase/postsynaptic density-95 coupling mechanisms and protects against neonatal ischemic degeneration of striatal neurons.
    Experimental neurology, 2010, Volume: 221, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Ischemia; Corpus Striatum; Disease Models, An

2010
Potent sigma 1-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine provides ischemic neuroprotection without altering dopamine accumulation in vivo in rats.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Blood Gas Analysis; Body Temperature; Brain Chemistry; Brai

2003
Hemiballismus following general anesthesia. A case report.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2003, Volume: 24, Issue:4

    Topics: Anesthesia, General; Anticonvulsants; Antipsychotic Agents; Brain Ischemia; Clonazepam; Dyskinesias;

2003
Analysis of inhibitory and excitatory actions of dopamine on chemoreceptor discharges of carotid body of cat in vivo.
    The Japanese journal of physiology, 1981, Volume: 31, Issue:5

    Topics: Animals; Brain Ischemia; Carotid Body; Cats; Chemoreceptor Cells; Dopamine; Electrophysiology; Halop

1981
[The acute psychiatric emergency].
    Zeitschrift fur Alternsforschung, 1981, Volume: 36, Issue:4

    Topics: Acute Disease; Aged; Alcoholism; Amitriptyline; Brain Ischemia; Cognition Disorders; Consciousness D

1981
Differential effects of amphetamine and haloperidol on recovery after global forebrain ischemia.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:4

    Topics: Animals; Brain Ischemia; Dextroamphetamine; Disease Models, Animal; Gerbillinae; Haloperidol; Male;

1994
Is c-Jun involved in nerve cell death following status epilepticus and hypoxic-ischaemic brain injury?
    Brain research. Molecular brain research, 1993, Volume: 18, Issue:4

    Topics: Animals; Apoptosis; Brain Ischemia; Dizocilpine Maleate; Genes, fos; Genes, jun; Haloperidol; Hypoxi

1993
Use of risperidone in psychotic disorder following ischemic brain damage.
    Journal of child and adolescent psychopharmacology, 1996,Spring, Volume: 6, Issue:1

    Topics: Adult; Brain Ischemia; Haloperidol; Humans; Male; Perphenazine; Psychotic Disorders; Risperidone

1996
Ballistic movements due to ischemic infarcts after intravenous heroin overdose: report of two cases.
    Clinical neurology and neurosurgery, 1997, Volume: 99, Issue:4

    Topics: Adult; Anti-Dyskinesia Agents; Basal Ganglia; Brain Ischemia; Coma; Corpus Striatum; Drug Overdose;

1997
Dopamine D2 receptor agonists protect against ischaemia-induced hippocampal neurodegeneration in global cerebral ischaemia.
    European journal of pharmacology, 1998, Jul-03, Volume: 352, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Brain Ischemia; B

1998
Neuroprotection from focal ischemia by 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) is dependent on treatment duration in rats.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:6

    Topics: Animals; Brain Ischemia; Cerebral Infarction; Haloperidol; Infusions, Intravenous; Male; Neuroprotec

1998
sigma(1)-receptor ligand 4-phenyl-1-(4-phenylbutyl)-piperidine affords neuroprotection from focal ischemia with prolonged reperfusion.
    Stroke, 2000, Volume: 31, Issue:4

    Topics: Animals; Behavior, Animal; Brain Ischemia; Cerebral Infarction; Drug Administration Schedule; Halope

2000
Neuroprotective effect of sigma(1)-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) is linked to reduced neuronal nitric oxide production.
    Stroke, 2001, Volume: 32, Issue:7

    Topics: Animals; Brain; Brain Ischemia; Citrulline; Enzyme Inhibitors; Haloperidol; Indazoles; Infarction, M

2001
Dopaminergic neurotransmission triggers ischemia-induced hyperactivity in Mongolian gerbils.
    Acta medica Okayama, 2001, Volume: 55, Issue:5

    Topics: Animals; Brain Ischemia; Dopamine; Dopamine Antagonists; Gerbillinae; Haloperidol; Hyperkinesis; Inj

2001
Testing drug effects against hypoxic damage of cultured neurons during long-term recovery.
    Life sciences, 1989, Volume: 45, Issue:9

    Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Brain Ischemia; Cell Count; Cell Survival; Cells,

1989