haloperidol has been researched along with Brain Neoplasms in 13 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Temozolomide resistance remains a major obstacle in the treatment of glioblastoma (GBM)." | 8.31 | The DRD2 Antagonist Haloperidol Mediates Autophagy-Induced Ferroptosis to Increase Temozolomide Sensitivity by Promoting Endoplasmic Reticulum Stress in Glioblastoma. ( Chen, H; Chen, K; Chen, L; Huang, A; Huang, Y; Li, C; Li, H; Lu, Y; Qi, S; Shi, L; Song, C; Wang, T; Zhong, C, 2023) |
| "In this study, the inhibitory effects of R(-)-NPA (R(-)-Propylnorapomorphine) and haloperidol on voltage-dependent K+ currents in rat C6 glioma cells (C6 cells) were observed by means of the whole-cell patch-clamp recording technique." | 7.69 | [Inhibition of voltage-dependent K+ currents in rat C6 glioma cells by haloperidol and R(-)-NPA]. ( He, SF; Xie, Z, 1997) |
| "Temozolomide (TMZ) has been the first-line chemotherapeutic agent used, although to achieve a satisfactory clinical effect." | 5.51 | Synergistic Suppression of Glioblastoma Cell Growth by Combined Application of Temozolomide and Dopamine D2 Receptor Antagonists. ( Gao, L; Huang, X; Jiang, X; Li, J; Liu, X; Liu, Z; Zeng, T, 2019) |
| "Temozolomide resistance remains a major obstacle in the treatment of glioblastoma (GBM)." | 4.31 | The DRD2 Antagonist Haloperidol Mediates Autophagy-Induced Ferroptosis to Increase Temozolomide Sensitivity by Promoting Endoplasmic Reticulum Stress in Glioblastoma. ( Chen, H; Chen, K; Chen, L; Huang, A; Huang, Y; Li, C; Li, H; Lu, Y; Qi, S; Shi, L; Song, C; Wang, T; Zhong, C, 2023) |
| "In this study, the inhibitory effects of R(-)-NPA (R(-)-Propylnorapomorphine) and haloperidol on voltage-dependent K+ currents in rat C6 glioma cells (C6 cells) were observed by means of the whole-cell patch-clamp recording technique." | 3.69 | [Inhibition of voltage-dependent K+ currents in rat C6 glioma cells by haloperidol and R(-)-NPA]. ( He, SF; Xie, Z, 1997) |
| "Glioblastoma multiforme is the most common malignant primary brain tumor in adults." | 1.72 | Antitumor Effect of Traditional Drugs for Neurological Disorders: Preliminary Studies in Neural Tumor Cell Lines. ( Doello, K; Mesas, C; Ortiz, R; Perazzoli, G; Quiñonero, F; Rama, AR; Vélez, C, 2022) |
| "Temozolomide (TMZ) has been the first-line chemotherapeutic agent used, although to achieve a satisfactory clinical effect." | 1.51 | Synergistic Suppression of Glioblastoma Cell Growth by Combined Application of Temozolomide and Dopamine D2 Receptor Antagonists. ( Gao, L; Huang, X; Jiang, X; Li, J; Liu, X; Liu, Z; Zeng, T, 2019) |
| "Pretreatment of haloperidol significantly reduced the radiotracer accumulation of [(99m)Tc]23 or [(99m)Tc]24 in the brain." | 1.40 | Novel cyclopentadienyl tricarbonyl (99m)tc complexes containing 1-piperonylpiperazine moiety: potential imaging probes for sigma-1 receptors. ( Brust, P; Cui, M; Deuther-Conrad, W; Jia, B; Jia, H; Li, D; Liu, B; Lu, J; Steinbach, J; Wang, X; Xie, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Doello, K | 3 |
| Mesas, C | 3 |
| Quiñonero, F | 3 |
| Rama, AR | 3 |
| Vélez, C | 3 |
| Perazzoli, G | 3 |
| Ortiz, R | 3 |
| Shi, L | 1 |
| Chen, H | 1 |
| Chen, K | 1 |
| Zhong, C | 1 |
| Song, C | 1 |
| Huang, Y | 1 |
| Wang, T | 1 |
| Chen, L | 1 |
| Li, C | 1 |
| Huang, A | 1 |
| Qi, S | 1 |
| Li, H | 1 |
| Lu, Y | 1 |
| Liu, Z | 1 |
| Jiang, X | 1 |
| Gao, L | 1 |
| Liu, X | 1 |
| Li, J | 1 |
| Huang, X | 1 |
| Zeng, T | 1 |
| Wang, X | 1 |
| Li, D | 1 |
| Deuther-Conrad, W | 1 |
| Lu, J | 1 |
| Xie, Y | 1 |
| Jia, B | 1 |
| Cui, M | 1 |
| Steinbach, J | 1 |
| Brust, P | 1 |
| Liu, B | 1 |
| Jia, H | 1 |
| Golan, M | 1 |
| Schreiber, G | 1 |
| Avissar, S | 1 |
| Ushizima, M | 2 |
| Amano, N | 1 |
| Guimarães, CA | 1 |
| Franzon, RC | 1 |
| Souza, EA | 1 |
| Schmutzler, KM | 1 |
| Montenegro, MA | 1 |
| Queiroz, Lde S | 1 |
| Cendes, F | 1 |
| Guerreiro, MM | 1 |
| Irvin, W | 1 |
| MacDonald, G | 1 |
| Smith, JK | 1 |
| Kim, WY | 1 |
| Burke, L | 1 |
| Berenberg, RA | 1 |
| Kim, KS | 1 |
| Morio, Y | 1 |
| Tanimoto, H | 1 |
| Yakushiji, T | 1 |
| Morimoto, Y | 1 |
| Xie, Z | 1 |
| He, SF | 1 |
| Wildbolz, A | 1 |
| Matakas, F | 1 |
2 reviews available for haloperidol and Brain Neoplasms
| Article | Year |
|---|---|
[Brain tumor].
Topics: Antipsychotic Agents; Benzodiazepines; Brain Neoplasms; Haloperidol; Humans; Hydrocephalus; Immunogl | 2003 |
[Diagnostic errors due to unilateral psychiatric or unilateral somatic appreciation (author's transl)].
Topics: Adjustment Disorders; Adult; Aged; Brain Neoplasms; Bronchial Neoplasms; Diagnostic Errors; Echinoco | 1979 |
11 other studies available for haloperidol and Brain Neoplasms
| Article | Year |
|---|---|
Antitumor Effect of Traditional Drugs for Neurological Disorders: Preliminary Studies in Neural Tumor Cell Lines.
Topics: Adult; Apoptosis; Biperiden; Brain Neoplasms; Cell Line, Tumor; Dextromethorphan; Fingolimod Hydroch | 2022 |
Antitumor Effect of Traditional Drugs for Neurological Disorders: Preliminary Studies in Neural Tumor Cell Lines.
Topics: Adult; Apoptosis; Biperiden; Brain Neoplasms; Cell Line, Tumor; Dextromethorphan; Fingolimod Hydroch | 2022 |
Antitumor Effect of Traditional Drugs for Neurological Disorders: Preliminary Studies in Neural Tumor Cell Lines.
Topics: Adult; Apoptosis; Biperiden; Brain Neoplasms; Cell Line, Tumor; Dextromethorphan; Fingolimod Hydroch | 2022 |
Antitumor Effect of Traditional Drugs for Neurological Disorders: Preliminary Studies in Neural Tumor Cell Lines.
Topics: Adult; Apoptosis; Biperiden; Brain Neoplasms; Cell Line, Tumor; Dextromethorphan; Fingolimod Hydroch | 2022 |
The DRD2 Antagonist Haloperidol Mediates Autophagy-Induced Ferroptosis to Increase Temozolomide Sensitivity by Promoting Endoplasmic Reticulum Stress in Glioblastoma.
Topics: Autophagy; Brain Neoplasms; Cell Line, Tumor; Dopamine D2 Receptor Antagonists; Drug Resistance, Neo | 2023 |
Synergistic Suppression of Glioblastoma Cell Growth by Combined Application of Temozolomide and Dopamine D2 Receptor Antagonists.
Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proli | 2019 |
Novel cyclopentadienyl tricarbonyl (99m)tc complexes containing 1-piperonylpiperazine moiety: potential imaging probes for sigma-1 receptors.
Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Glioma; Haloperidol; Ligands; Male; Mice, Inbred | 2014 |
Antidepressants elevate GDNF expression and release from C₆ glioma cells in a β-arrestin1-dependent, CREB interactive pathway.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents | 2011 |
Abnormal behavior in children with temporal lobe epilepsy and ganglioglioma.
Topics: Anticonvulsants; Antipsychotic Agents; Brain Neoplasms; Child; Electroencephalography; Epilepsy, Tem | 2004 |
Dexamethasone-induced posterior reversible encephalopathy syndrome.
Topics: Anti-Inflammatory Agents; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dexamethasone; Dopamine A | 2007 |
Choreoballismus: a nonhemorrhagic complication of venous angiomas.
Topics: Brain Neoplasms; Caudate Nucleus; Chorea; Clonazepam; Haloperidol; Hemangioma; Humans; Male; Middle | 1984 |
Characterization of the currents induced by sigma ligands in NCB20 neuroblastoma cells.
Topics: Animals; Antipsychotic Agents; Brain Neoplasms; Cricetinae; Electrophysiology; Haloperidol; Ligands; | 1994 |
[Inhibition of voltage-dependent K+ currents in rat C6 glioma cells by haloperidol and R(-)-NPA].
Topics: Animals; Apomorphine; Biological Transport, Active; Brain Neoplasms; Dopamine Agonists; Dopamine Ant | 1997 |
[Staining technics and histochemical reactions in thin synthetic resin sections for light microscopic examination].
Topics: Aniline Compounds; Animals; Brain Neoplasms; Epoxy Resins; Histocytochemistry; Humans; Medulloblasto | 1969 |