Page last updated: 2024-10-28

haloperidol and Blepharoptosis

haloperidol has been researched along with Blepharoptosis in 24 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Blepharoptosis: Drooping of the upper lid due to deficient development or paralysis of the levator palpebrae muscle.

Research Excerpts

ExcerptRelevanceReference
"In a separate test, muscular rigidity is induced by the opioid, fentanyl, and subsequently, test compounds are assessed for their ability to reverse muscular rigidity."1.28An in vivo alpha-2 assay reversal of opioid-induced muscular rigidity and neuroleptic-induced ptosis. ( Benvenga, MJ; Capacchione, JF; Del Vecchio, RA; Jerussi, TP, 1992)
"Severe vomiting was evoked by Apo in dogs, but not by Eph even when lethal dose (20 mg."1.28[Comparison of central stimulating effects between ephedrine and apomorphine]. ( Li, BH; Li, Q, 1991)
"Methylphenidate was weakly effective against clonazepam and haloperidol but inactive versus CER."1.27Neuroleptic-like effects of ceruletide and cholecystokinin octapeptide: interactions with apomorphine, methylphenidate and picrotoxin. ( Zetler, G, 1983)
"Thus, catalepsy is a robust endogenously regulated circadian response that is only slowly influenced by altered lighting conditions which dissociate this rhythm of neuroleptic response from that of spontaneous general arousal."1.26Circadian changes in behavioral effects of haloperidol in rats. ( Baldessarini, RJ; Campbell, A, 1982)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199018 (75.00)18.7374
1990's5 (20.83)18.2507
2000's1 (4.17)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maryanoff, BE1
McComsey, DF1
Gardocki, JF1
Shank, RP1
Costanzo, MJ1
Nortey, SO1
Schneider, CR1
Setler, PE1
Zetler, G2
Campbell, A3
Baldessarini, RJ3
Subarnas, A1
Tadano, T1
Oshima, Y1
Kisara, K1
Ohizumi, Y1
El Yacoubi, M1
Ledent, C1
Parmentier, M1
Bertorelli, R1
Ongini, E1
Costentin, J2
Vaugeois, JM1
Niemegeers, CJ7
Laduron, PM1
Pedigo, NW1
Schallert, T1
Overstreet, DH1
Ling, NC1
Ragan, P1
Reisine, TD1
Yamamura, HI1
Ito, K1
Nurimoto, S1
Shintomi, K1
Kowa, Y1
Yamamura, M1
Ishida, R1
Janssen, PA5
Schellekens, KH2
Lenaerts, FM2
Wauquier, A2
Benvenga, MJ1
Del Vecchio, RA1
Capacchione, JF1
Jerussi, TP1
Li, Q1
Li, BH1
Duterte-Boucher, D1
Kamenka, JM1
Rao, KV2
Puri, VN2
el-Sawaf, HA1
Diwan, PK1
Alvarez, FM1
Dresse, A1
Pinchard, A1
Schaper, WK1
van Nueten, JM1
Verbruggen, FJ3
Borgman, RJ1
Baylor, MR1
McPhillips, JJ1
Stitzel, RE1
Lal, H1
Cools, AR1

Reviews

1 review available for haloperidol and Blepharoptosis

ArticleYear
Pharmacology and biochemistry of haloperidol.
    Proceedings of the Royal Society of Medicine, 1976, Volume: 69 suppl 1

    Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Blepharoptosis; Bra

1976

Other Studies

23 other studies available for haloperidol and Blepharoptosis

ArticleYear
Pyrroloisoquinoline antidepressants. 2. In-depth exploration of structure-activity relationships.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Catecholamines; Chemical Phenomena; Chemistry

1987
Clonidine and yohimbine separate the sedation and the ptosis caused by cholecystokinin octapeptide and ceruletide.
    European journal of pharmacology, 1984, Jul-13, Volume: 102, Issue:2

    Topics: Animals; Apomorphine; Blepharoptosis; Catalepsy; Ceruletide; Clonidine; Drug Antagonism; Haloperidol

1984
Neuroleptic-like effects of ceruletide and cholecystokinin octapeptide: interactions with apomorphine, methylphenidate and picrotoxin.
    European journal of pharmacology, 1983, Oct-28, Volume: 94, Issue:3-4

    Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Blepharoptosis; Body Temperature; Ceru

1983
Effects of maturation and aging on behavioral responses to haloperidol in the rat.
    Psychopharmacology, 1981, Volume: 73, Issue:3

    Topics: Aging; Animals; Behavior, Animal; Blepharoptosis; Dose-Response Relationship, Drug; Haloperidol; Mal

1981
Circadian changes in behavioral effects of haloperidol in rats.
    Psychopharmacology, 1982, Volume: 77, Issue:2

    Topics: Animals; Behavior, Animal; Blepharoptosis; Catalepsy; Circadian Rhythm; Dose-Response Relationship,

1982
Tolerance to behavioral effects of haloperidol.
    Life sciences, 1981, Sep-28, Volume: 29, Issue:13

    Topics: Animals; Behavior, Animal; Blepharoptosis; Body Weight; Catalepsy; Drug Tolerance; Growth; Haloperid

1981
Pharmacological properties of beta-amyrin palmitate, a novel centrally acting compound, isolated from Lobelia inflata leaves.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:6

    Topics: Animals; Antidepressive Agents; Apomorphine; Blepharoptosis; Catalepsy; Central Nervous System; Dose

1993
Adenosine A2A receptor antagonists are potential antidepressants: evidence based on pharmacology and A2A receptor knockout mice.
    British journal of pharmacology, 2001, Volume: 134, Issue:1

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Blepharoptosis; Disease Models, Animal; Dopamine A

2001
Inhibition of in vivo 3H-spiperone binding by the proposed antipsychotic Des-Tyr1-gamma-endorphin.
    European journal of pharmacology, 1979, Dec-20, Volume: 60, Issue:4

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Blepharoptosis; Brain; Butyrophenones; Catalepsy; E

1979
[Pharmacological studies of an antipschotic agent, penfluridol. (1). The central pharmacological actions].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1976, Volume: 72, Issue:7

    Topics: Agonistic Behavior; Animals; Apomorphine; Avoidance Learning; Blepharoptosis; Body Temperature; Cata

1976
Clopimozide (R 29 764), a new highly potent and orally long-acting neuroleptic of the diphenylbutylpiperidine series.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:8

    Topics: Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Benzimidazoles; Blepharoptosis; Body Tem

1975
An in vivo alpha-2 assay reversal of opioid-induced muscular rigidity and neuroleptic-induced ptosis.
    Journal of pharmacological and toxicological methods, 1992, Volume: 27, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blepharoptosis; Drug Evaluation, P

1992
[Comparison of central stimulating effects between ephedrine and apomorphine].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:5

    Topics: Animals; Apomorphine; Blepharoptosis; Catalepsy; Ephedrine; Haloperidol; Male; Mice; Motor Activity;

1991
Comparison of the effects of three indirect dopamine agonists, GK 13, GBR 12783 and dexamphetamine on behavioural tests involving central catecholaminergic transmissions.
    Psychopharmacology, 1990, Volume: 101, Issue:3

    Topics: Animals; Behavior, Animal; Blepharoptosis; Body Temperature; Brain Chemistry; Catecholamines; Dextro

1990
Further studies on the neuroleptic profile of manassantin A.
    European journal of pharmacology, 1990, Apr-25, Volume: 179, Issue:3

    Topics: Adenylyl Cyclase Inhibitors; Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Binding,

1990
Preliminary evaluation of manassantin A, a potential neuroleptic agent from Saururus cernuus.
    Pharmacological research communications, 1987, Volume: 19, Issue:9

    Topics: Amphetamine; Animals; Antipsychotic Agents; Blepharoptosis; Body Temperature; Catalepsy; Furans; Hal

1987
Pimozide, a chemically novel, highly potent and orally long-acting neuroleptic drug. I. The comparative pharmacology of pimozide, haloperidol, and chlorpromazine.
    Arzneimittel-Forschung, 1968, Volume: 18, Issue:3

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Benzimidazoles; Blepharoptosis; Body Temperatur

1968
Bromoperidol, a new potent neuroleptic of the butyrophenone series. Comparative pharmacology of bromoperidol and haloperidol.
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:1

    Topics: Administration, Oral; Amphetamine; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Bleph

1974
Alpha-methyldopamine derivatives. Synthesis and pharmacology.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:4

    Topics: Animals; Apomorphine; Blepharoptosis; Body Temperature; Depression, Chemical; Dihydroxyphenylalanine

1974
Differential antagonism by naloxone of inhibitory effects of haloperidol and morphine on brain self-stimulation.
    Psychopharmacologia, 1974, Volume: 37, Issue:4

    Topics: Animals; Behavior, Animal; Blepharoptosis; Brain; Catalepsy; Catatonia; Electric Stimulation; Electr

1974
The function of dopamine and its antagonism in the caudate nucleus of cats in relation to the stereotyped behaviour.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 194, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Blepharoptosis; Cats; Caudate Nucleus; Dextroamphetamine; Do

1971
The influence of various neuroleptic drugs on shock avoidance responding in rats. II. Nondiscriminated Sidman avoidance procedure with alternate reinforcement and extinction periods and analysis of the interresponse times (IRT's).
    Psychopharmacologia, 1969, Volume: 16, Issue:3

    Topics: Animals; Antidepressive Agents; Avoidance Learning; Benperidol; Blepharoptosis; Butyrophenones; Cata

1969
The influence of various neuroleptic drugs on noise escape response in rats.
    Psychopharmacologia, 1970, Volume: 18, Issue:3

    Topics: Animals; Antidepressive Agents; Avoidance Learning; Benperidol; Blepharoptosis; Butyrophenones; Cata

1970