haloperidol has been researched along with Autism in 52 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the study was to investigate safety, efficacy and tolerability of risperidone in comparison with haloperidol in the long-term treatment of autistic disorder." | 9.13 | Comparison of long-term efficacy and safety of risperidone and haloperidol in children and adolescents with autistic disorder. An open label maintenance study. ( Baykara, A; Baykara, B; Dirik, E; Emiroglu, FN; Gencer, O; Miral, S, 2008) |
| "The ABC-C and the Childhood Autism Rating Scale scores improved with cyproheptadine." | 9.11 | Cyproheptadine in the treatment of autistic disorder: a double-blind placebo-controlled trial. ( Akhondzadeh, S; Amini, H; Erfani, S; Gudarzi, SS; Mohammadi, MR; Tehrani-Doost, M; Yasamy, MT, 2004) |
| "Clomipramine, haloperidol, and placebo were compared with baseline in the treatment of autism, and overall outcome, specific symptoms, and side effects were examined." | 9.09 | Clomipramine versus haloperidol in the treatment of autistic disorder: a double-blind, placebo-controlled, crossover study. ( Gow, R; Konstantareas, M; Parker, K; Remington, G; Sloman, L, 2001) |
| "The findings suggest that olanzapine is a promising treatment for children with autistic disorder." | 9.09 | Olanzapine versus haloperidol in children with autistic disorder: an open pilot study. ( Cater, J; Choudhury, MS; Delaney, MA; Malone, RP; Sheikh, RM, 2001) |
| "The aim of the study was to investigate safety, efficacy and tolerability of risperidone in comparison with haloperidol in the long-term treatment of autistic disorder." | 5.13 | Comparison of long-term efficacy and safety of risperidone and haloperidol in children and adolescents with autistic disorder. An open label maintenance study. ( Baykara, A; Baykara, B; Dirik, E; Emiroglu, FN; Gencer, O; Miral, S, 2008) |
| "The ABC-C and the Childhood Autism Rating Scale scores improved with cyproheptadine." | 5.11 | Cyproheptadine in the treatment of autistic disorder: a double-blind placebo-controlled trial. ( Akhondzadeh, S; Amini, H; Erfani, S; Gudarzi, SS; Mohammadi, MR; Tehrani-Doost, M; Yasamy, MT, 2004) |
| "Clomipramine, haloperidol, and placebo were compared with baseline in the treatment of autism, and overall outcome, specific symptoms, and side effects were examined." | 5.09 | Clomipramine versus haloperidol in the treatment of autistic disorder: a double-blind, placebo-controlled, crossover study. ( Gow, R; Konstantareas, M; Parker, K; Remington, G; Sloman, L, 2001) |
| "The findings suggest that olanzapine is a promising treatment for children with autistic disorder." | 5.09 | Olanzapine versus haloperidol in children with autistic disorder: an open pilot study. ( Cater, J; Choudhury, MS; Delaney, MA; Malone, RP; Sheikh, RM, 2001) |
| " We assessed the relationship between pre- and perinatal complications and TD/WD in a sample of 118 children with autism who participated in an ongoing long-term prospective study of the efficacy and safety of haloperidol." | 3.69 | Haloperidol-related dyskinesias and pre- and perinatal complications in autistic children. ( Adams, PB; Armenteros, JL; Campbell, M; Eisenberg, ZW, 1995) |
| "The long-term effects of haloperidol on weight were assessed in 30 children, 25 males and 5 females, diagnosed with autistic disorder whose ages ranged from 3." | 3.68 | Haloperidol withdrawal and weight changes in autistic children. ( Anderson, LT; Campbell, M; Malone, RP; Shay, J; Silva, RR, 1993) |
| "Haloperidol was shown to be a powerful therapeutic agent when administered for 4 weeks and free of side effects; at doses ranging from 0." | 2.66 | The effects of haloperidol on discrimination learning and behavioral symptoms in autistic children. ( Adams, P; Anderson, LT; Campbell, M; Perry, R; Shell, J; Small, AM, 1989) |
| "Bilateral intraocular pressures were monitored before and after the first 7 ECTs and intermittently after ECT for 10 months of maintenance ECT." | 1.40 | Stability of intraocular pressure after retinal reattachment surgery during electroconvulsive therapy for intractable self-injury in a 12-year-old autistic boy. ( Reti, IM; Wachtel, LE; Ying, H, 2014) |
| "Subjects were children with autism requiring pharmacotherapy for target symptoms." | 1.30 | Neuroleptic-related dyskinesias in autistic children: a prospective, longitudinal study. ( Adams, PB; Armenteros, JL; Campbell, M; Eisenberg, ZW; Malone, RP; Overall, JE, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (50.00) | 18.7374 |
| 1990's | 15 (28.85) | 18.2507 |
| 2000's | 8 (15.38) | 29.6817 |
| 2010's | 2 (3.85) | 24.3611 |
| 2020's | 1 (1.92) | 2.80 |
| Authors | Studies |
|---|---|
| Syamkumar, S | 1 |
| Dossetor, D | 1 |
| Wachtel, LE | 1 |
| Reti, IM | 1 |
| Ying, H | 1 |
| Nakamae, T | 1 |
| Ribeiro, KM | 1 |
| Assumpção, FB | 1 |
| Valente, KD | 1 |
| Akhondzadeh, S | 1 |
| Erfani, S | 1 |
| Mohammadi, MR | 1 |
| Tehrani-Doost, M | 1 |
| Amini, H | 1 |
| Gudarzi, SS | 1 |
| Yasamy, MT | 1 |
| Nilsson, M | 1 |
| Carlsson, A | 1 |
| Markinhuhta, KR | 1 |
| Sonesson, C | 1 |
| Pettersson, F | 1 |
| Gullme, M | 1 |
| Carlsson, ML | 1 |
| Strawn, JR | 1 |
| Keck, PE | 1 |
| Gencer, O | 1 |
| Emiroglu, FN | 1 |
| Miral, S | 1 |
| Baykara, B | 1 |
| Baykara, A | 1 |
| Dirik, E | 1 |
| Realmuto, GM | 1 |
| Main, B | 1 |
| Campbell, M | 20 |
| Anderson, LT | 8 |
| Deutsch, SI | 4 |
| Green, WH | 6 |
| Grega, DM | 1 |
| Perry, R | 8 |
| Small, AM | 9 |
| Caplan, R | 1 |
| Cohen, IL | 3 |
| Posner, D | 2 |
| Triebel, D | 1 |
| Armenteros, JL | 2 |
| Adams, PB | 3 |
| Eisenberg, ZW | 2 |
| Sanchez, LE | 1 |
| Uysal, S | 1 |
| Hallin, A | 1 |
| Minderaa, RB | 3 |
| Anderson, GM | 3 |
| Volkmar, FR | 3 |
| Akkerhuis, GW | 2 |
| Cohen, DJ | 4 |
| Ernst, M | 2 |
| Devi, L | 1 |
| Silva, RR | 2 |
| Gonzalez, NM | 1 |
| Malone, RP | 6 |
| Shay, J | 1 |
| Brasić, JR | 1 |
| Barnett, JY | 1 |
| Overall, JE | 4 |
| Kobayashi, R | 1 |
| Kurita, H | 1 |
| Remington, G | 1 |
| Sloman, L | 1 |
| Konstantareas, M | 1 |
| Parker, K | 1 |
| Gow, R | 1 |
| Cater, J | 1 |
| Sheikh, RM | 1 |
| Choudhury, MS | 1 |
| Delaney, MA | 1 |
| Heath, A | 1 |
| Meier, M | 2 |
| Samit, C | 1 |
| Sachar, EJ | 1 |
| Hoshino, Y | 1 |
| Yashima, Y | 1 |
| Ishige, K | 1 |
| Kaneko, M | 1 |
| Kumashiro, H | 1 |
| Johnson, WT | 1 |
| Caparulo, BK | 1 |
| Stárková, L | 1 |
| Wiedermann, J | 1 |
| Wong, SE | 1 |
| Floyd, J | 1 |
| Innocent, AJ | 1 |
| Woolsey, JE | 1 |
| Locascio, JJ | 2 |
| Kafantaris, V | 2 |
| Lynch, NS | 1 |
| Ghaziuddin, M | 1 |
| Tsai, LY | 1 |
| Ghaziuddin, N | 1 |
| Choroco, MC | 1 |
| Spencer, EK | 3 |
| Littlejohns, CS | 1 |
| Clarke, DJ | 1 |
| Corbett, JA | 1 |
| Meiselas, KD | 1 |
| Oberfield, R | 1 |
| Peselow, ED | 1 |
| Angrist, B | 1 |
| Fisher, W | 1 |
| Piazza, CC | 1 |
| Page, TJ | 1 |
| Adams, P | 2 |
| Shell, J | 1 |
| Harcherick, D | 1 |
| McDaniel, KD | 1 |
| Poland, RE | 1 |
| Rubin, RT | 1 |
| Lynch, N | 1 |
| Curren, EL | 1 |
| Nobler, MS | 1 |
| van Engeland, H | 1 |
| Freedman, DX | 1 |
| Hoder, EL | 1 |
| McPhedran, P | 1 |
| Hansen, CR | 1 |
| Young, JG | 1 |
| Milstoc, M | 1 |
| Platovsky, G | 1 |
| Wolsky, BB | 1 |
| Die Trill, ML | 1 |
| Meiselas, K | 1 |
| Golden, RR | 1 |
| Ornitz, EM | 1 |
| Sandyk, R | 1 |
| Faretra, G | 1 |
| Dooher, L | 1 |
| Dowling, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Galantamine Versus Placebo in Childhood Autism[NCT00252603] | Phase 3 | 20 participants | Interventional | 2004-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for haloperidol and Autism
| Article | Year |
|---|---|
[Diversity of obsessive-compulsive disorder and pharmacotherapy associated with obsessive-compulsive spectrum disorders].
Topics: Antipsychotic Agents; Autistic Disorder; Body Dysmorphic Disorders; Clomipramine; Comorbidity; Disru | 2011 |
Psychiatric drug treatment in children.
Topics: Adolescent; Amphetamines; Antipsychotic Agents; Anxiety; Autistic Disorder; Behavior Therapy; Child; | 1979 |
13 trials available for haloperidol and Autism
| Article | Year |
|---|---|
Cyproheptadine in the treatment of autistic disorder: a double-blind placebo-controlled trial.
Topics: Autistic Disorder; Basal Ganglia Diseases; Child; Child, Preschool; Cyproheptadine; Double-Blind Met | 2004 |
Comparison of long-term efficacy and safety of risperidone and haloperidol in children and adolescents with autistic disorder. An open label maintenance study.
Topics: Adolescent; Adolescent Behavior; Antipsychotic Agents; Autistic Disorder; Child; Child Behavior; Dos | 2008 |
Haloperidol in the treatment of infantile autism: effects on learning and behavioral symptoms.
Topics: Autistic Disorder; Child; Child, Preschool; Clinical Trials as Topic; Discrimination Learning; Doubl | 1984 |
The effects of haloperidol on learning and behavior in autistic children.
Topics: Autistic Disorder; Child; Child Behavior; Child, Preschool; Discrimination Learning; Double-Blind Me | 1982 |
A comparison of live and videotape ratings: clomipramine and haloperidol in autism.
Topics: Autistic Disorder; Child; Child, Preschool; Clomipramine; Double-Blind Method; Female; Haloperidol; | 1995 |
Plasma beta-endorphin levels, naltrexone, and haloperidol in autistic children.
Topics: Autistic Disorder; beta-Endorphin; Child; Child, Preschool; Double-Blind Method; Female; Haloperidol | 1993 |
Clomipramine versus haloperidol in the treatment of autistic disorder: a double-blind, placebo-controlled, crossover study.
Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Autistic Disorder; Basal | 2001 |
Olanzapine versus haloperidol in children with autistic disorder: an open pilot study.
Topics: Antipsychotic Agents; Autistic Disorder; Benzodiazepines; Child; Child Development Disorders, Pervas | 2001 |
A comparison of haloperidol and behavior therapy and their interaction in autistic children.
Topics: Autistic Disorder; Behavior Therapy; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind | 1978 |
A comparison of haloperidol, behavior therapy, and their interaction in autistic children [proceedings].
Topics: Autistic Disorder; Behavior Therapy; Child; Child, Preschool; Clinical Trials as Topic; Female; Halo | 1979 |
The effects of haloperidol on discrimination learning and behavioral symptoms in autistic children.
Topics: Autistic Disorder; Child, Preschool; Clinical Trials as Topic; Discrimination Learning; Double-Blind | 1989 |
Neuroleptic-related dyskinesias in autistic children: a prospective study.
Topics: Autistic Disorder; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Dyskinesi | 1985 |
Should autistic children be treated with haloperidol?
Topics: Autistic Disorder; Child; Clinical Trials as Topic; Dyskinesia, Drug-Induced; Haloperidol; Hospitali | 1985 |
37 other studies available for haloperidol and Autism
| Article | Year |
|---|---|
Severe movement disorder and psychosis from haloperidol withdrawal in a 7-year-old girl with autism.
Topics: Antipsychotic Agents; Autistic Disorder; Child; Female; Haloperidol; Humans; Movement Disorders; Psy | 2021 |
Stability of intraocular pressure after retinal reattachment surgery during electroconvulsive therapy for intractable self-injury in a 12-year-old autistic boy.
Topics: Aggression; Anticonvulsants; Antipsychotic Agents; Autistic Disorder; Child; Electroconvulsive Thera | 2014 |
[Landau-Kleffner and autistic regression: the importance of differential diagnosis].
Topics: Anticonvulsants; Autistic Disorder; Child, Preschool; Diagnosis, Differential; Electroencephalograph | 2002 |
The dopaminergic stabiliser ACR16 counteracts the behavioural primitivization induced by the NMDA receptor antagonist MK-801 in mice: implications for cognition.
Topics: Animals; Autistic Disorder; Behavior, Animal; Cognition; Dizocilpine Maleate; Dopamine Antagonists; | 2004 |
Risperidone: new indication. Behavioural disorders in children with autism or mental disabilities: no progress.
Topics: Adolescent; Antipsychotic Agents; Autistic Disorder; Child; Child Behavior Disorders; Child, Prescho | 2006 |
Early bicarbonate loading and dantroline for ziprasidone/haloperidol-induced neuroleptic malignant syndrome.
Topics: Adolescent; Antipsychotic Agents; Autistic Disorder; Combined Modality Therapy; Dantrolene; Disrupti | 2006 |
Coincidence of Tourette's disorder and infantile autism.
Topics: Adolescent; Autistic Disorder; Dopamine; Haloperidol; Humans; Male; Neurotransmitter Agents; Tourett | 1982 |
Psychopharmacological treatment of children with the syndrome of autism.
Topics: Amphetamines; Antipsychotic Agents; Autistic Disorder; Child; Child, Preschool; Haloperidol; Humans; | 1984 |
Behavioral effects of haloperidol in young autistic children. An objective analysis using a within-subjects reversal design.
Topics: Autistic Disorder; Child; Child, Preschool; Female; Haloperidol; Humans; Male | 1980 |
A study of haloperidol in young autistic children: a within-subjects design using objective rating scales.
Topics: Autistic Disorder; Child; Child, Preschool; Double-Blind Method; Female; Haloperidol; Humans; Male; | 1980 |
Haloperidol-related dyskinesias and pre- and perinatal complications in autistic children.
Topics: Autistic Disorder; Child; Child, Preschool; Diagnosis, Differential; Dyskinesia, Drug-Induced; Femal | 1995 |
Noradrenergic and adrenergic functioning in autism.
Topics: Adolescent; Adult; Anticonvulsants; Autistic Disorder; Brain; Child; Epinephrine; Female; Haloperido | 1994 |
Haloperidol withdrawal and weight changes in autistic children.
Topics: Autistic Disorder; Body Weight; Child; Child, Preschool; Female; Haloperidol; Humans; Male; Prospect | 1993 |
Hyperkinesias in a prepubertal boy with autistic disorder treated with haloperidol and valproic acid.
Topics: Anti-Dyskinesia Agents; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Autistic Dis | 1997 |
Neuroleptic-related dyskinesias in autistic children: a prospective, longitudinal study.
Topics: Antipsychotic Agents; Autistic Disorder; Child; Child, Preschool; Dyskinesia, Drug-Induced; Female; | 1997 |
Perception metamorphosis phenomenon in autism.
Topics: Adolescent; Auditory Perception; Autistic Disorder; Female; Haloperidol; Humans; Intellectual Disabi | 1998 |
Brief report: delusional disorder in a male adolescent with high-functioning PDDNOS.
Topics: Adolescent; Adult; Antipsychotic Agents; Autistic Disorder; Child Development Disorders, Pervasive; | 1999 |
Effects of small doses of haloperidol on autistic children.
Topics: Autistic Disorder; Child, Preschool; Female; Haloperidol; Humans; Intellectual Disability; Male | 1979 |
Pica and elevated blood lead level in autistic and atypical children.
Topics: Adolescent; Autistic Disorder; Cerebrospinal Fluid Proteins; Child; Child, Preschool; Dimercaprol; E | 1976 |
Our experience with incisive neuroleptic drugs in child psychiatry.
Topics: Antipsychotic Agents; Autistic Disorder; Child; Haloperidol; Humans; Mental Disorders; Obsessive-Com | 1991 |
Applying a DRO schedule and compliance training to reduce aggressive and self-injurious behavior in an autistic man: a case report.
Topics: Adult; Aggression; Autistic Disorder; Behavior Therapy; Carbamazepine; Combined Modality Therapy; Ha | 1991 |
Factors related to haloperidol response and dyskinesias in autistic children.
Topics: Autistic Disorder; Child, Preschool; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Infant; | 1991 |
Brief report: haloperidol treatment of trichotillomania in a boy with autism and mental retardation.
Topics: Autistic Disorder; Child; Dose-Response Relationship, Drug; Education of Intellectually Disabled; Ha | 1991 |
Stereotypies and tardive dyskinesia: abnormal movements in autistic children.
Topics: Adolescent; Autistic Disorder; Child, Preschool; Dyskinesia, Drug-Induced; Haloperidol; Humans; Infa | 1990 |
Tourette-like disorder in Asperger's syndrome.
Topics: Adolescent; Autistic Disorder; Female; Haloperidol; Humans; Male; Pregnancy; Prenatal Exposure Delay | 1990 |
Differentiation of stereotypies from neuroleptic-related dyskinesias in autistic children.
Topics: Autistic Disorder; Blinking; Child; Child, Preschool; Diagnosis, Differential; Dyskinesia, Drug-Indu | 1989 |
Assessing independent and interactive effects of behavioral and pharmacologic interventions for a client with dual diagnoses.
Topics: Autistic Disorder; Behavior Therapy; Child; Combined Modality Therapy; Follow-Up Studies; Hallucinat | 1989 |
Whole blood serotonin and tryptophan in autism: temporal stability and the effects of medication.
Topics: Adolescent; Adult; Anticonvulsants; Autistic Disorder; Female; Haloperidol; Humans; Male; Phenothiaz | 1989 |
Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 2).
Topics: Adolescent; Antipsychotic Agents; Autistic Disorder; Benzodiazepines; Child; Chlorpromazine; Haloper | 1986 |
Plasma growth hormone response to insulin-induced hypoglycemia in infantile autism: a pilot study.
Topics: Autistic Disorder; Child, Preschool; Female; Growth Hormone; Haloperidol; Humans; Hypoglycemia; Hypo | 1986 |
Long-term efficacy of haloperidol in autistic children: continuous versus discontinuous drug administration.
Topics: Autistic Disorder; Child; Child, Preschool; Drug Administration Schedule; Dyskinesia, Drug-Induced; | 1989 |
Tourette-like symptoms associated with neuroleptic therapy in an autistic child.
Topics: Autistic Disorder; Child, Preschool; Diagnosis, Differential; Dyskinesia, Drug-Induced; Haloperidol; | 1989 |
[Current developments in the treatment of autistic children].
Topics: Autistic Disorder; Behavior Therapy; Child; Child Development; Haloperidol; Humans; Psychotherapy | 1989 |
Whole blood serotonin in autistic and normal subjects.
Topics: Adolescent; Adult; Anticonvulsants; Autistic Disorder; Blood Platelets; Child; Child, Preschool; Chr | 1987 |
Cholinesterase activities in blood in infantile autism.
Topics: Acetylcholinesterase; Autistic Disorder; Butyrylcholinesterase; Cholinesterases; Erythrocytes; Femal | 1987 |
Further speculations on possible dopamine-opioid link in autism.
Topics: Autistic Disorder; Dopamine; Endorphins; Haloperidol; Humans | 1986 |
Comparison of haloperidol and fluphenazine in disturbed children.
Topics: Aggression; Anxiety; Autistic Disorder; Child; Child, Preschool; Female; Fluphenazine; Haloperidol; | 1970 |