Page last updated: 2024-10-28

haloperidol and Atrophy

haloperidol has been researched along with Atrophy in 17 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"Cerebral cortical gray was examined volumetrically in 19 patients with schizophrenia before and following 28 days of treatment with two SGAs (risperidone and ziprasidone; n = 13) or a FGA (haloperidol; n = 6)."5.11Cerebral cortical gray expansion associated with two second-generation antipsychotics. ( Christensen, JD; Garver, DL; Holcomb, JA, 2005)
"Schizophrenia is a neurodevelopmental disorder associated with persistent symptomatology, severe functional disability, and residual morbidity characteristic of neurodegenerative brain diseases."1.34Neuroprotection: a therapeutic strategy to prevent deterioration associated with schizophrenia. ( Jarskog, LF; Lieberman, JA; Perkins, DO, 2007)
"Cranial magnetic resonance image (MRI) of the patient showed bilateral symmetric hyperintensity in the caudate nucleus and putamen."1.32Transient tic disorder following carbon monoxide poisoning. ( Alioglu, Z; Aynaci, M; Boz, C; Sari, A, 2004)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19904 (23.53)18.7374
1990's6 (35.29)18.2507
2000's4 (23.53)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stiefelhagen, P1
Vernon, AC1
Crum, WR1
Lerch, JP1
Chege, W1
Natesan, S1
Modo, M1
Cooper, JD1
Williams, SC1
Kapur, S1
Konopaske, GT1
Lange, N1
Coyle, JT1
Benes, FM1
Alioglu, Z1
Boz, C1
Sari, A1
Aynaci, M1
Garver, DL2
Holcomb, JA1
Christensen, JD2
Lieberman, JA1
Perkins, DO1
Jarskog, LF1
Snider, SR1
Factor, SA1
Podskalny, GD1
Barron, KD1
Lawson, WB1
Karson, CN1
Mowadat, HR1
Kerr, EE1
StClair, D1
Nair, TR1
Holcomb, J1
Ramberg, J1
Kingsbury, S1
Maruka, Y1
Esumi, E1
Kojima, S1
van Kammen, DP1
Peters, J1
Yao, J1
Neylan, T1
Beuger, M1
Pontius, E1
O'Connor, DT1
Lazarus, A1
Smith, RC1
Baumgartner, R1
Ravichandran, GK1
Largen, J1
Calderon, M1
Burd, A1
Mauldin, M1
Morihisa, JM1
McAnulty, GB1
Walsh, AC1
Walsh, BH1

Reviews

1 review available for haloperidol and Atrophy

ArticleYear
Cerebellar pathology in schizophrenia--cause or consequence?
    Neuroscience and biobehavioral reviews, 1982,Spring, Volume: 6, Issue:1

    Topics: Animals; Apomorphine; Atrophy; Behavior, Animal; Brain Stem; Cats; Cerebellar Diseases; Cerebellum;

1982

Trials

2 trials available for haloperidol and Atrophy

ArticleYear
Cerebral cortical gray expansion associated with two second-generation antipsychotics.
    Biological psychiatry, 2005, Jul-01, Volume: 58, Issue:1

    Topics: Adult; Antipsychotic Agents; Atrophy; Cerebral Cortex; Cognition Disorders; Female; Follow-Up Studie

2005
Atrophic and static (neurodevelopmental) schizophrenic psychoses: premorbid functioning, symptoms and neuroleptic response.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 21, Issue:1

    Topics: Adult; Aging; Alcohol Drinking; Algorithms; Antipsychotic Agents; Atrophy; Brain; Cerebral Ventricle

1999

Other Studies

14 other studies available for haloperidol and Atrophy

ArticleYear
[In process].
    Medizinische Monatsschrift fur Pharmazeuten, 2016, Volume: 39, Issue:9

    Topics: Antipsychotic Agents; Atrophy; Brain; Cerebral Cortex; Dopamine; Dose-Response Relationship, Drug; G

2016
Reduced cortical volume and elevated astrocyte density in rats chronically treated with antipsychotic drugs-linking magnetic resonance imaging findings to cellular pathology.
    Biological psychiatry, 2014, Jun-15, Volume: 75, Issue:12

    Topics: Animals; Antipsychotic Agents; Astrocytes; Atrophy; Benzodiazepines; Cell Count; Cerebral Cortex; Ha

2014
Prefrontal cortical dendritic spine pathology in schizophrenia and bipolar disorder.
    JAMA psychiatry, 2014, Dec-01, Volume: 71, Issue:12

    Topics: Animals; Atrophy; Bipolar Disorder; Case-Control Studies; Clozapine; Dendritic Spines; Female; Front

2014
Transient tic disorder following carbon monoxide poisoning.
    Journal of neuroradiology = Journal de neuroradiologie, 2004, Volume: 31, Issue:3

    Topics: Atrophy; Carbon Monoxide Poisoning; Caudate Nucleus; Child; Dominance, Cerebral; Follow-Up Studies;

2004
Neuroprotection: a therapeutic strategy to prevent deterioration associated with schizophrenia.
    CNS spectrums, 2007, Volume: 12, Issue:3 Suppl 4

    Topics: Adolescent; Adult; Antipsychotic Agents; Atrophy; Benzodiazepines; Cerebral Cortex; Child; Cognition

2007
Persistent neuroleptic-induced rigidity and dystonia in AIDS dementia complex: a clinico-pathological case report.
    Journal of the neurological sciences, 1994, Dec-01, Volume: 127, Issue:1

    Topics: Adult; AIDS Dementia Complex; Antipsychotic Agents; Astrocytes; Atrophy; Brain; Cell Count; Dystonia

1994
Clinical correlates of body weight changes in schizophrenia.
    The Journal of neuropsychiatry and clinical neurosciences, 1994,Spring, Volume: 6, Issue:2

    Topics: Adult; Atrophy; Brain; Cerebral Ventricles; Energy Intake; Female; Haloperidol; Humans; Male; Psychi

1994
Sporadic Pick's disease in a 28-year-old woman.
    The British journal of psychiatry : the journal of mental science, 1993, Volume: 162

    Topics: Adult; Atrophy; Carbamazepine; Dementia; Electroconvulsive Therapy; Female; Frontal Lobe; Haloperido

1993
Tandospirone, a promising alternative drug in the treatment of chorea.
    Internal medicine (Tokyo, Japan), 2000, Volume: 39, Issue:12

    Topics: Animals; Atrophy; Cerebral Cortex; Chorea; Dementia; Dopamine Antagonists; Female; Fluvoxamine; Halo

2000
CSF chromogranin A-like immunoreactivity in schizophrenia. Assessment of clinical and biochemical relationships.
    Schizophrenia research, 1991, Volume: 6, Issue:1

    Topics: Adult; Arousal; Atrophy; Brain; Chromogranin A; Chromogranins; Haloperidol; Homovanillic Acid; Human

1991
EPS, NMS, and AIDS.
    Biological psychiatry, 1990, Sep-15, Volume: 28, Issue:6

    Topics: Adult; AIDS Dementia Complex; Atrophy; Cerebral Cortex; Dyskinesia, Drug-Induced; Haloperidol; Human

1990
Cortical atrophy and white matter density in the brains of schizophrenics and clinical response to neuroleptics.
    Acta psychiatrica Scandinavica, 1987, Volume: 75, Issue:1

    Topics: Adult; Antipsychotic Agents; Atrophy; Cerebral Cortex; Female; Haloperidol; Humans; Male; Middle Age

1987
Structure and function: brain electrical activity mapping and computed tomography in schizophrenia.
    Biological psychiatry, 1985, Volume: 20, Issue:1

    Topics: Adult; Atrophy; Brain; Brain Mapping; Cerebral Ventricles; Delta Rhythm; Electroencephalography; Evo

1985
Presenile dementia: further experience with an anticoagulant-psychotherapy regimen.
    Journal of the American Geriatrics Society, 1974, Volume: 22, Issue:10

    Topics: Adult; Aged; Anticoagulants; Anxiety; Atrophy; Brain Diseases; Dementia; Dicumarol; Fear; Female; Ha

1974