haloperidol has been researched along with Arrhythmias, Cardiac in 31 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Results of these analyses suggest that olanzapine, as therapeutically administered to patients with schizophrenia and related psychoses, does not contribute to QTc prolongation resulting in potentially fatal ventricular arrhythmias." | 9.09 | Analysis of the QTc interval during olanzapine treatment of patients with schizophrenia and related psychosis. ( Beasley, CM; Berg, PH; Czekalla, J; Dellva, MA; Grundy, S, 2001) |
| "We report on three patients with acute coronary syndromes who developed QT interval prolongation associated with intravenous haloperidol use." | 7.70 | Corrected QT interval prolongation associated with intravenous haloperidol in acute coronary syndromes. ( Block, PC; Douglas, PH, 2000) |
| "A patient is described who developed hypokalemia and cardiac arrhythmia after acute intoxication with haloperidol." | 7.67 | Prolonged Q-T interval and hypokalemia caused by haloperidol. ( Aunsholt, NA, 1989) |
| "Results of these analyses suggest that olanzapine, as therapeutically administered to patients with schizophrenia and related psychoses, does not contribute to QTc prolongation resulting in potentially fatal ventricular arrhythmias." | 5.09 | Analysis of the QTc interval during olanzapine treatment of patients with schizophrenia and related psychosis. ( Beasley, CM; Berg, PH; Czekalla, J; Dellva, MA; Grundy, S, 2001) |
| "Haloperidol decanoate is a typical antipsychotic drug used as maintenance therapy for schizophrenia and mood disorders formulated as an ester for intramuscular injection." | 3.85 | An acute oral intoxication with haloperidol decanoate. ( Dekkers, BGJ; Eck, RJ; Ter Maaten, JC; Touw, DJ, 2017) |
| "N-n-butyl haloperidol (F(2)), a novel compound of quaternary ammonium salt derivatives of haloperidol, was reported to antagonize myocardial ischemia/reperfusion injuries." | 3.76 | Cardiac electrophysiological and antiarrhythmic effects of N-n-butyl haloperidol iodide. ( Chen, YC; Gao, FF; Hao, SY; Huang, ZQ; Liu, XP; Shi, GG; Zhang, YM; Zhou, YQ, 2010) |
| "Haloperidol (HPL), well known antipsychotic drug can induce a marked QT prolongation and polymorphic arrhythmias." | 3.75 | Modulation of haloperidol induced electrophysiological alterations on cardiac action potential by various risk factors and gender difference. ( Prathapan, A; Raghu, KG; Singh, R; Yadav, GK, 2009) |
| "Medical records were reviewed retrospectively to identify consecutive patients who were admitted to our neuropsychiatry service with the presenting complaint of dementia (DSM-IV) with agitation and who were given intramuscular ziprasidone and then administered an electrocardiogram (ECG) (N = 23)." | 3.73 | A retrospective study of the safety of intramuscular ziprasidone in agitated elderly patients. ( Brown, FW; Greco, KE; Tune, LE; Van Horn, WA, 2005) |
| "To compare the rate of ventricular arrhythmia, sudden death and unexplained or unattended death among users of thioridazine and haloperidol." | 3.72 | Comparative cardiac safety of low-dose thioridazine and low-dose haloperidol. ( Bilker, WB; Glasser, DB; Hennessy, S; Kimmel, SE; Knauss, JS; Margolis, DJ; Morrison, MF; Reynolds, RF; Strom, BL, 2004) |
| "Patients with schizophrenia treated with clozapine, haloperidol, risperidone, or thioridazine; a control group of patients with glaucoma; and a control group of patients with psoriasis." | 3.71 | Cardiac arrest and ventricular arrhythmia in patients taking antipsychotic drugs: cohort study using administrative data. ( Bilker, WB; Glasser, DB; Hennessy, S; Kimmel, SE; Knauss, JS; Margolis, DJ; Morrison, MF; Reynolds, RF; Strom, BL, 2002) |
| "Haloperidol (HPL), a widely used antipsychotic drug, is known to induce serious ventricular arrhythmias." | 3.70 | Haloperidol prolongs diastolic phase of Ca(2+) transient in cardiac myocytes. ( Genka, C; Hirota, Y; Hoshiai, K; Hoshiai, M; Ishida, H; Nakazawa, H, 1999) |
| "We report on three patients with acute coronary syndromes who developed QT interval prolongation associated with intravenous haloperidol use." | 3.70 | Corrected QT interval prolongation associated with intravenous haloperidol in acute coronary syndromes. ( Block, PC; Douglas, PH, 2000) |
| "A patient is described who developed hypokalemia and cardiac arrhythmia after acute intoxication with haloperidol." | 3.67 | Prolonged Q-T interval and hypokalemia caused by haloperidol. ( Aunsholt, NA, 1989) |
| "We examined the incidence of arrhythmias, changes in heart rate, and prolongation of QT interval in isolated Langendorff-perfused rat and guinea pig hearts after they were exposed to nanomolar concentrations of haloperidol." | 1.35 | Apparent desensitization of the effects of sigma receptor ligand haloperidol in isolated rat and guinea pig hearts after chronic treatment. ( Fialova, K; Jarkovsky, J; Krizanova, O; Novakova, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (38.71) | 18.7374 |
| 1990's | 2 (6.45) | 18.2507 |
| 2000's | 13 (41.94) | 29.6817 |
| 2010's | 4 (12.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jia, L | 1 |
| Sun, H | 1 |
| Vivier, D | 1 |
| Bennis, K | 1 |
| Lesage, F | 1 |
| Ducki, S | 1 |
| Dekkers, BGJ | 1 |
| Eck, RJ | 1 |
| Ter Maaten, JC | 1 |
| Touw, DJ | 1 |
| Raghu, KG | 1 |
| Singh, R | 1 |
| Prathapan, A | 1 |
| Yadav, GK | 1 |
| Kovács, G | 1 |
| Fialova, K | 1 |
| Krizanova, O | 1 |
| Jarkovsky, J | 1 |
| Novakova, M | 1 |
| Gao, FF | 1 |
| Hao, SY | 1 |
| Huang, ZQ | 1 |
| Zhang, YM | 1 |
| Zhou, YQ | 1 |
| Chen, YC | 1 |
| Liu, XP | 1 |
| Shi, GG | 1 |
| Meyer-Massetti, C | 1 |
| Cheng, CM | 1 |
| Sharpe, BA | 1 |
| Meier, CR | 1 |
| Guglielmo, BJ | 1 |
| Hennessy, S | 2 |
| Bilker, WB | 2 |
| Knauss, JS | 2 |
| Margolis, DJ | 2 |
| Kimmel, SE | 2 |
| Reynolds, RF | 2 |
| Glasser, DB | 2 |
| Morrison, MF | 2 |
| Strom, BL | 2 |
| MIETTINEN, P | 1 |
| EEROLA, R | 1 |
| POENTINEN, P | 1 |
| Li, L | 1 |
| Desai, M | 1 |
| Desta, Z | 1 |
| Flockhart, D | 1 |
| Greco, KE | 1 |
| Tune, LE | 1 |
| Brown, FW | 1 |
| Van Horn, WA | 1 |
| Roberts-Thomson, KC | 1 |
| Teo, KS | 1 |
| Young, GD | 1 |
| Turbott, J | 1 |
| Cairns, FJ | 1 |
| Menes, C | 1 |
| Burra, P | 1 |
| Hoaken, PC | 1 |
| Skorga, P | 1 |
| Nunnery, C | 1 |
| Furrows, DC | 1 |
| Ishida, H | 1 |
| Hoshiai, K | 1 |
| Hoshiai, M | 1 |
| Genka, C | 1 |
| Hirota, Y | 1 |
| Nakazawa, H | 1 |
| Douglas, PH | 1 |
| Block, PC | 1 |
| Czekalla, J | 1 |
| Beasley, CM | 1 |
| Dellva, MA | 1 |
| Berg, PH | 1 |
| Grundy, S | 1 |
| Cohen, H | 1 |
| Loewenthal, U | 1 |
| Matar, M | 1 |
| Kotler, M | 1 |
| Remijnse, PL | 1 |
| Eeckhout, AM | 1 |
| van Guldener, C | 1 |
| Mehta, D | 1 |
| Mehta, S | 1 |
| Petit, J | 1 |
| Shriner, W | 1 |
| Briggs, AH | 1 |
| Delallo, LJ | 1 |
| Cameron, OG | 1 |
| Helke, CJ | 1 |
| Gillis, RA | 1 |
| Aunsholt, NA | 1 |
| Johnstone, M | 1 |
| Pratt, IT | 1 |
| Wallace, WA | 1 |
| Abelmann, WH | 1 |
| Norman, JC | 1 |
3 reviews available for haloperidol and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Struc | 2016 |
The FDA extended warning for intravenous haloperidol and torsades de pointes: how should institutions respond?
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Arrhythmias, Cardiac; Drug-Related Side Effects and A | 2010 |
Runaway demand pacemaker: report, in vitro reproduction, and review.
Topics: Aged; Arrhythmias, Cardiac; Body Fluids; Electrodes; Epoxy Resins; Heart Block; Heart Rate; Humans; | 1970 |
1 trial available for haloperidol and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Analysis of the QTc interval during olanzapine treatment of patients with schizophrenia and related psychosis.
Topics: Acute Disease; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Antipsychotic Agent | 2001 |
27 other studies available for haloperidol and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant | 2008 |
An acute oral intoxication with haloperidol decanoate.
Topics: Administration, Oral; Antipsychotic Agents; Arrhythmias, Cardiac; Charcoal; Electrocardiography; Fem | 2017 |
Modulation of haloperidol induced electrophysiological alterations on cardiac action potential by various risk factors and gender difference.
Topics: Action Potentials; Animals; Antipsychotic Agents; Arrhythmias, Cardiac; Electrolytes; Female; Gonada | 2009 |
[The decision of the pharmacologic authority--the doubts of a clinician].
Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Arrhythmias, Cardiac; Drug and Narcoti | 2009 |
Apparent desensitization of the effects of sigma receptor ligand haloperidol in isolated rat and guinea pig hearts after chronic treatment.
Topics: Animals; Arrhythmias, Cardiac; Electrocardiography; Guinea Pigs; Haloperidol; Heart; Heart Rate; Rat | 2009 |
Cardiac electrophysiological and antiarrhythmic effects of N-n-butyl haloperidol iodide.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channels, L-Type; | 2010 |
Cardiac arrest and ventricular arrhythmia in patients taking antipsychotic drugs: cohort study using administrative data.
Topics: Adult; Aged; Antipsychotic Agents; Arrhythmias, Cardiac; Clozapine; Cohort Studies; Confidence Inter | 2002 |
EKG CHANGES DURING SURGERY FOR STRABISMUS.
Topics: Adolescent; Anesthesia; Arrhythmias, Cardiac; Bradycardia; Bundle-Branch Block; Cardiac Complexes, P | 1964 |
Comparative cardiac safety of low-dose thioridazine and low-dose haloperidol.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Arrhythmias, Cardiac; Child; Child, Preschool; Cohort | 2004 |
QT analysis: a complex answer to a 'simple' problem.
Topics: Adult; Antipsychotic Agents; Arrhythmias, Cardiac; Biomarkers; Computer Simulation; Cross-Over Studi | 2004 |
A retrospective study of the safety of intramuscular ziprasidone in agitated elderly patients.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Arrhythmias, Cardiac; Dementia; Electrocardiography; | 2005 |
Drug-induced Brugada syndrome with ST-T wave alternans and long QT.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Arrhythmias, Cardiac; | 2007 |
Sudden death and neuroleptic medication.
Topics: Arrhythmias, Cardiac; Death, Sudden; Haloperidol; Heart Arrest; Humans; Male; Middle Aged; Paranoid | 1984 |
Untoward effects following combined neuroleptic-lithium therapy. Cardiac arrhythmias and seizure.
Topics: Adult; Arrhythmias, Cardiac; Bipolar Disorder; Chlorpromazine; Drug Therapy, Combination; Epilepsy, | 1980 |
How to spot...and care for...the patient with Lown-Ganong-Levine syndrome.
Topics: Arrhythmias, Cardiac; Electrocardiography; Female; Haloperidol; Humans; Male; Middle Aged; Nursing A | 1981 |
Cardiotoxicity associated with use of intravenous haloperidol.
Topics: Antipsychotic Agents; Arrhythmias, Cardiac; Haloperidol; Humans; Injections, Intravenous; Mental Dis | 1999 |
Haloperidol prolongs diastolic phase of Ca(2+) transient in cardiac myocytes.
Topics: Animals; Antipsychotic Agents; Arrhythmias, Cardiac; Calcium; Cells, Cultured; Haloperidol; Heart; M | 1999 |
Corrected QT interval prolongation associated with intravenous haloperidol in acute coronary syndromes.
Topics: Aged; Angina, Unstable; Antipsychotic Agents; Arrhythmias, Cardiac; Electrocardiography; Haloperidol | 2000 |
[Heart rate variability in schizophrenic patients treated with antipsychotic agents].
Topics: Adult; Antipsychotic Agents; Arrhythmias, Cardiac; Benzodiazepines; Clozapine; Female; Haloperidol; | 2001 |
[Sudden death following a single oral administration of haloperidol].
Topics: Administration, Oral; Adult; Antipsychotic Agents; Arrhythmias, Cardiac; Cardiomyopathies; Death, Su | 2002 |
Cardiac arrhythmia and haloperidol.
Topics: Adult; Arrhythmias, Cardiac; Bipolar Disorder; Blood Pressure; Cardiac Complexes, Premature; Haloper | 1979 |
The effects of haloperidol on ouabain cardiac inotropy and toxicity.
Topics: Animals; Arrhythmias, Cardiac; Depression, Chemical; Haloperidol; Heart; Heart Atria; Heart Rate; In | 1978 |
Safe use of haloperidol in a patient with cardiac dysrhythmia.
Topics: Adolescent; Arrhythmias, Cardiac; Haloperidol; Humans; Male; Psychotic Disorders | 1978 |
Centrally mediated protective effects of dopamine agonists on digitalis-induced ventricular arrhythmias.
Topics: Animals; Apomorphine; Arrhythmias, Cardiac; Blood Pressure; Brain; Cardiovascular System; Cats; Dece | 1978 |
Prolonged Q-T interval and hypokalemia caused by haloperidol.
Topics: Arrhythmias, Cardiac; Electrocardiography; Female; Haloperidol; Humans; Hypokalemia; Long QT Syndrom | 1989 |
Alprenolol during halothane anaesthesia in surgical patients.
Topics: Adolescent; Adult; Anesthesia, Inhalation; Anesthetics; Arrhythmias, Cardiac; Atropine; Blood Pressu | 1968 |
Twilight sleep after infarction.
Topics: Arrhythmias, Cardiac; Blood Pressure; Electroencephalography; Haloperidol; Humans; Injections, Intra | 1971 |