haloperidol has been researched along with Allodynia in 16 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Haloperidol (HAL) is a compound that shows a high affinity with these receptors, acting as an antagonist." | 5.46 | Haloperidol Decreases Hyperalgesia and Allodynia Induced by Chronic Constriction Injury. ( Espinosa-Juárez, JV; Jaramillo-Morales, OA; López-Muñoz, FJ, 2017) |
| "We evaluated the effects of haloperidol and its metabolites on capsaicin-induced mechanical hypersensitivity (allodynia) and on nociceptive pain induced by punctate mechanical stimuli in mice." | 3.75 | Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors. ( Baeyens, JM; Cendán, CM; Cobos, EJ; Del Pozo, E; Entrena, JM; Nieto, FR, 2009) |
| "In addition, the patient complained of hyperalgesia with heat and mechanical allodynia." | 1.91 | Calcium Silicate-based Sealer Extrusion into the Mandibular Canal: 3 Different Recovery Outcomes-A Report of 3 Cases. ( Jeong, JW; Kirkpatrick, T; Stanley, E; Strother, KK, 2023) |
| "Mechanic and cold allodynia were evaluated for 3 h and alterations in serum concentration of TNF-α determined." | 1.46 | Antiallodynic Activity of Ceftriaxone and Clavulanic Acid in Acute Administration is Associated with Serum TNF-α Modulation and Activation of Dopaminergic and Opioidergic Systems. ( Jaimez, R; Ochoa-Aguilar, A; Plancarte-Sánchez, R; Rodríguez, R; Sotomayor-Sobrino, MA; Ventura-Martinez, R, 2017) |
| "Haloperidol (HAL) is a compound that shows a high affinity with these receptors, acting as an antagonist." | 1.46 | Haloperidol Decreases Hyperalgesia and Allodynia Induced by Chronic Constriction Injury. ( Espinosa-Juárez, JV; Jaramillo-Morales, OA; López-Muñoz, FJ, 2017) |
| "Methadone is an atypical opioid that inhibits hyperalgesia through NMDA-blockade, especially at low doses." | 1.39 | The use of very-low-dose methadone for palliative pain control and the prevention of opioid hyperalgesia. ( Bruera, E; Buckley, JS; Salpeter, SR, 2013) |
| "At the time of peak hyperalgesia, WIN55,212-2 (1-30mg/kg) or vehicle was administered intraperitoneally and forelimb grip force was measured 0." | 1.32 | A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain. ( Croft, DL; Hamamoto, DT; Kehl, LJ; Norsted, BD; Simone, DA; Wacnik, PW; Wilcox, GL, 2003) |
| "To clarify the mechanism of the hyperalgesia in SART mice and the mode of the antinociceptive action of neurotropin in this model, the influence of systemically administered neurotransmitter related drugs was studied." | 1.28 | Mechanism of hyperalgesia in SART stressed (repeated cold stress) mice: antinociceptive effect of neurotropin. ( Hata, T; Kawamura, M; Miura, T; Namimatsu, A; Ohara, H; Yoneda, R, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 7 (43.75) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, H | 1 |
| Altenbach, RJ | 1 |
| Carr, TL | 1 |
| Chandran, P | 2 |
| Hsieh, GC | 2 |
| Lewis, LG | 1 |
| Manelli, AM | 1 |
| Milicic, I | 1 |
| Marsh, KC | 1 |
| Miller, TR | 1 |
| Strakhova, MI | 1 |
| Vortherms, TA | 1 |
| Wakefield, BD | 1 |
| Wetter, JM | 1 |
| Witte, DG | 1 |
| Honore, P | 1 |
| Esbenshade, TA | 1 |
| Brioni, JD | 1 |
| Cowart, MD | 1 |
| Schläger, T | 1 |
| Schepmann, D | 1 |
| Lehmkuhl, K | 1 |
| Holenz, J | 2 |
| Vela, JM | 2 |
| Buschmann, H | 2 |
| Wünsch, B | 1 |
| Nelson, DW | 1 |
| Frost, JM | 1 |
| Tietje, KR | 1 |
| Florjancic, AS | 1 |
| Ryther, K | 1 |
| Carroll, WA | 1 |
| Dart, MJ | 1 |
| Daza, AV | 1 |
| Hooker, BA | 1 |
| Grayson, GK | 1 |
| Fan, Y | 1 |
| Garrison, TR | 1 |
| El-Kouhen, OF | 1 |
| Yao, B | 1 |
| Pai, M | 1 |
| Zhu, C | 1 |
| Meyer, MD | 1 |
| Díaz, JL | 1 |
| Cuberes, R | 1 |
| Berrocal, J | 1 |
| Contijoch, M | 1 |
| Christmann, U | 1 |
| Fernández, A | 1 |
| Port, A | 1 |
| Laggner, C | 1 |
| Serafini, MT | 1 |
| Burgueño, J | 1 |
| Zamanillo, D | 1 |
| Merlos, M | 1 |
| Almansa, C | 1 |
| Déciga-Campos, M | 1 |
| Villafán-Gutiérrez, R | 1 |
| Espinosa-Juárez, JV | 2 |
| Jaramillo-Morales, OA | 2 |
| López-Muñoz, FJ | 2 |
| Ochoa-Aguilar, A | 1 |
| Sotomayor-Sobrino, MA | 1 |
| Jaimez, R | 1 |
| Rodríguez, R | 1 |
| Plancarte-Sánchez, R | 1 |
| Ventura-Martinez, R | 1 |
| Salpeter, SR | 1 |
| Buckley, JS | 1 |
| Bruera, E | 1 |
| Martins, DF | 1 |
| Emer, AA | 1 |
| Batisti, AP | 1 |
| Donatello, N | 1 |
| Carlesso, MG | 1 |
| Mazzardo-Martins, L | 1 |
| Venzke, D | 1 |
| Micke, GA | 1 |
| Pizzolatti, MG | 1 |
| Piovezan, AP | 1 |
| dos Santos, AR | 1 |
| Entrena, JM | 1 |
| Cobos, EJ | 1 |
| Nieto, FR | 1 |
| Cendán, CM | 1 |
| Baeyens, JM | 1 |
| Del Pozo, E | 1 |
| Kehl, LJ | 1 |
| Hamamoto, DT | 1 |
| Wacnik, PW | 1 |
| Croft, DL | 1 |
| Norsted, BD | 1 |
| Wilcox, GL | 1 |
| Simone, DA | 1 |
| Gonzalez, JP | 1 |
| Sewell, RD | 1 |
| Spencer, PS | 1 |
| Barber, A | 1 |
| Bartoszyk, GD | 1 |
| Greiner, HE | 1 |
| Mauler, F | 1 |
| Murray, RD | 1 |
| Seyfried, CA | 1 |
| Simon, M | 1 |
| Gottschlich, R | 1 |
| Harting, J | 1 |
| Lues, I | 1 |
| King, MA | 1 |
| Rossi, GC | 1 |
| Chang, AH | 1 |
| Williams, L | 1 |
| Pasternak, GW | 1 |
| Ohara, H | 1 |
| Kawamura, M | 1 |
| Namimatsu, A | 1 |
| Miura, T | 1 |
| Yoneda, R | 1 |
| Hata, T | 1 |
| Stanley, E | 1 |
| Strother, KK | 1 |
| Kirkpatrick, T | 1 |
| Jeong, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Atlas Cedarwood Essential Oil Aromatherapy on Sleep Quality Among Patients With Coronary Heart Disease: a Randomized Controlled Trial[NCT03830554] | 96 participants (Actual) | Interventional | 2018-07-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 other studies available for haloperidol and Allodynia
| Article | Year |
|---|---|
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; | 2008 |
Combination of two pharmacophoric systems: synthesis and pharmacological evaluation of spirocyclic pyranopyrazoles with high σ₁ receptor affinity.
Topics: Analgesics; Animals; Brain; Guinea Pigs; Hyperalgesia; In Vitro Techniques; Liver; Mice; Pyrans; Pyr | 2011 |
Synthesis and evaluation of 2-amido-3-carboxamide thiophene CB₂ receptor agonists for pain management.
Topics: Amides; Analgesics; Animals; Biological Availability; Cell Line, Tumor; Dose-Response Relationship, | 2012 |
Synthesis and biological evaluation of the 1-arylpyrazole class of σ(1) receptor antagonists: identification of 4-{2-[5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy]ethyl}morpholine (S1RA, E-52862).
Topics: Animals; Brain; Female; Guinea Pigs; HEK293 Cells; Humans; Hyperalgesia; In Vitro Techniques; Male; | 2012 |
Synergistic interaction between haloperidol and gabapentin in a model of neuropathic nociception in rat.
Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug | 2021 |
Antiallodynic Activity of Ceftriaxone and Clavulanic Acid in Acute Administration is Associated with Serum TNF-α Modulation and Activation of Dopaminergic and Opioidergic Systems.
Topics: Animals; Ceftriaxone; Clavulanic Acid; Cold Temperature; Dopamine Antagonists; Gene Expression Regul | 2017 |
Haloperidol Decreases Hyperalgesia and Allodynia Induced by Chronic Constriction Injury.
Topics: Amines; Analgesics; Animals; Antipsychotic Agents; Chronic Disease; Constriction, Pathologic; Cycloh | 2017 |
The use of very-low-dose methadone for palliative pain control and the prevention of opioid hyperalgesia.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; California; Dose-Response Relationship, Drug; Ex | 2013 |
Inhalation of Cedrus atlantica essential oil alleviates pain behavior through activation of descending pain modulation pathways in a mouse model of postoperative pain.
Topics: Administration, Inhalation; Adrenergic alpha-2 Receptor Antagonists; alpha-Methyltyrosine; Analgesic | 2015 |
Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors.
Topics: Analysis of Variance; Animals; Brain; Capsaicin; Disease Models, Animal; Dopamine Antagonists; Dose- | 2009 |
A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain.
Topics: Animals; Benzoxazines; Calcium Channel Blockers; Camphanes; Cannabinoids; Carrageenan; Catalepsy; Di | 2003 |
Dopaminergic involvement in the hyperalgesic effect of nomifensine.
Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Hot Temperature; Hyperalgesia; Hyp | 1981 |
Central and peripheral actions of the novel kappa-opioid receptor agonist, EMD 60400.
Topics: Analgesics; Animals; Brain; Carrageenan; Dihydroxyphenylalanine; Diuresis; Electric Stimulation; For | 1994 |
Spinal analgesic activity of orphanin FQ/nociceptin and its fragments.
Topics: Analgesics; Animals; Antisense Elements (Genetics); Cloning, Molecular; Drug Synergism; Exons; Halop | 1997 |
Mechanism of hyperalgesia in SART stressed (repeated cold stress) mice: antinociceptive effect of neurotropin.
Topics: 5-Hydroxytryptophan; Animals; Cold Temperature; Drug Interactions; Fenclonine; Haloperidol; Hyperalg | 1991 |
Calcium Silicate-based Sealer Extrusion into the Mandibular Canal: 3 Different Recovery Outcomes-A Report of 3 Cases.
Topics: Epoxy Resins; Humans; Hyperalgesia; Mandibular Canal; Paresthesia; Root Canal Filling Materials; Roo | 2023 |