Page last updated: 2024-10-28

haloperidol and Affective Disorders

haloperidol has been researched along with Affective Disorders in 22 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Research Excerpts

ExcerptRelevanceReference
"When comparing treatment effects on individual symptoms frequently occurring in patients with dementia, risperidone significantly improved symptoms of agitation, wandering, diurnal rhythm disturbance and anxieties, among other symptoms, compared with haloperidol."9.12Comparative efficacy of risperidone versus haloperidol on behavioural and psychological symptoms of dementia. ( Choi, SK; Greenspan, AJ; Suh, GH, 2006)
"The effects of risperidone on affective symptoms were determined by an analysis of pooled data from six double-blind trials of risperidone versus haloperidol in 1254 patients with chronic schizophrenia."8.80Effects of risperidone on affective symptoms in patients with schizophrenia. ( De Smedt, C; Lemmens, P; Peuskens, J; Van Baelen, B, 2000)
" Since the effects of carbamazepine on substance P content are identical with previously described effects of lithium, an alteration in substance P neurotransmission may be one of the neurochemical bases of common clinical and behavioral effects of carbamazepine and lithium on affective disorders."7.67Effects of chronic treatment with trihexyphenidyl and carbamazepine alone or in combination with haloperidol on substance P content in rat brain: a possible implication of substance P in affective disorders. ( Mataga, N; Mitsushio, H; Takashima, M; Toru, M, 1988)
"When comparing treatment effects on individual symptoms frequently occurring in patients with dementia, risperidone significantly improved symptoms of agitation, wandering, diurnal rhythm disturbance and anxieties, among other symptoms, compared with haloperidol."5.12Comparative efficacy of risperidone versus haloperidol on behavioural and psychological symptoms of dementia. ( Choi, SK; Greenspan, AJ; Suh, GH, 2006)
"The effects of risperidone on affective symptoms were determined by an analysis of pooled data from six double-blind trials of risperidone versus haloperidol in 1254 patients with chronic schizophrenia."4.80Effects of risperidone on affective symptoms in patients with schizophrenia. ( De Smedt, C; Lemmens, P; Peuskens, J; Van Baelen, B, 2000)
"Lithium carbonate is the single most important long-term treatment for recurrent affective disorders."4.76Lithium. ( DePaulo, JR, 1984)
" Since the effects of carbamazepine on substance P content are identical with previously described effects of lithium, an alteration in substance P neurotransmission may be one of the neurochemical bases of common clinical and behavioral effects of carbamazepine and lithium on affective disorders."3.67Effects of chronic treatment with trihexyphenidyl and carbamazepine alone or in combination with haloperidol on substance P content in rat brain: a possible implication of substance P in affective disorders. ( Mataga, N; Mitsushio, H; Takashima, M; Toru, M, 1988)
"Challenging behaviour in patients with intellectual disability may be caused by physical, psychological and environmental factors."2.50[Challenging behaviour in patients with intellectual disability]. ( de Kuijper, GM; Vrijmoeth, P, 2014)
"Co-morbid substance abuse was uncommon."1.39Prevalence and clinical presentation of HIV positive female psychiatric inpatients. ( Uys, H, 2013)
"To compare the side effect profile of risperidone with that of oral haloperidol in patients with no previous exposure to antipsychotic drugs (APDs)."1.30Neurologic side effects in neuroleptic-naive patients treated with haloperidol or risperidone. ( Mazurek, MF; Rosebush, PI, 1999)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19907 (31.82)18.7374
1990's1 (4.55)18.2507
2000's7 (31.82)29.6817
2010's6 (27.27)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Abaatyo, J1
Favina, A1
Kaggwa, MM1
Uys, H1
Vilibić, M1
Jukić, V1
Vidović, A1
Brecić, P1
de Kuijper, GM1
Vrijmoeth, P1
Dankert, ME1
Brensinger, CM1
Metzger, KL1
Li, C1
Koleva, SG1
Mesén, A1
Laprade, B1
Wiguna, T1
Han, C1
Farooq, S1
Severus, WE1
Gayares, JG1
Langosch, JM1
Lallart, X1
Tateno, M1
Mihai, A1
Nair, SR1
Belmaker, R1
Rybakowski, J1
Owe-Larsson, B1
Kane, JM1
Johnstone, EC1
MacIntyre, DJ1
Malhotra, S1
González-Pinto, A1
Mosquera, F1
Babb, SM1
Habib pour, E1
Fatemi, SS1
Swanson, C1
Adler, C1
Young, A1
Hoeft, F1
Sivakumar, K1
Radoeva, PD1
Lallart, EA1
Bilker, WB1
Siegel, SJ1
Danovich, L1
Weinreb, O1
Youdim, MB1
Silver, H1
Krzyzosiak, A1
Szyszka-Niagolov, M1
Wietrzych, M1
Gobaille, S1
Muramatsu, S1
Krezel, W1
Rhodius-Meester, HF1
Kuper, IM1
Otten, HM1
Hamburger, HL1
Webster, JP1
Lamberton, PH1
Donnelly, CA1
Torrey, EF1
Suh, GH1
Greenspan, AJ1
Choi, SK1
Papazisis, G1
Kouvelas, D1
Mastrogianni, A1
Karastergiou, A1
Thomas, C1
Tatham, A1
Jakubowski, S1
Davis, J1
Conn, LM1
Lion, JR1
Brambilla, F1
Genazzani, AR1
Facchinetti, F1
Parrini, D1
Petraglia, F1
Sacchetti, E1
Scarone, S1
Gustalla, A1
D'Antona, N1
DePaulo, JR1
Smith, RC1
Vroulis, G1
Misra, CH1
Schoolar, J1
DeJohn, C1
Korivi, P1
Leelavathi, DE1
Arzu, D1
Rosebush, PI1
Mazurek, MF1
Peuskens, J1
Van Baelen, B1
De Smedt, C1
Lemmens, P1
Iqbal, MM1
Gundlapalli, SP1
Ryan, WG1
Ryals, T1
Passman, TE1
Sultzer, DL1
Gray, KF1
Gunay, I1
Wheatley, MV1
Mahler, ME1
Mitsushio, H1
Takashima, M1
Mataga, N1
Toru, M1

Reviews

5 reviews available for haloperidol and Affective Disorders

ArticleYear
[Challenging behaviour in patients with intellectual disability].
    Nederlands tijdschrift voor geneeskunde, 2014, Volume: 158

    Topics: Aggression; Agonistic Behavior; Child; Female; Haloperidol; Humans; Intellectual Disability; Male; M

2014
Pharmacologic approaches to violence.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:4

    Topics: Aggression; Anticonvulsants; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Be

1984
Lithium.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:3

    Topics: Aggression; Bipolar Disorder; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, C

1984
Effects of risperidone on affective symptoms in patients with schizophrenia.
    International clinical psychopharmacology, 2000, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Double-Blind Method; Female; Halop

2000
Effects of antimanic mood-stabilizing drugs on fetuses, neonates, and nursing infants.
    Southern medical journal, 2001, Volume: 94, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Antimanic Agents; Benzodiazepines; Breast Feed

2001

Trials

2 trials available for haloperidol and Affective Disorders

ArticleYear
Comparative efficacy of risperidone versus haloperidol on behavioural and psychological symptoms of dementia.
    International journal of geriatric psychiatry, 2006, Volume: 21, Issue:7

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Anxiety Disorders; Cross-Over Studies; Dementia; Doub

2006
Does behavioral improvement with haloperidol or trazodone treatment depend on psychosis or mood symptoms in patients with dementia?
    Journal of the American Geriatrics Society, 2001, Volume: 49, Issue:10

    Topics: Aged; Alzheimer Disease; Analysis of Variance; Antidepressive Agents, Second-Generation; Antipsychot

2001

Other Studies

15 other studies available for haloperidol and Affective Disorders

ArticleYear
Absconding among admitted patients with bipolar affective disorder diagnosis in Uganda.
    BMC psychiatry, 2023, 05-04, Volume: 23, Issue:1

    Topics: Bipolar Disorder; Haloperidol; Hospitalization; Humans; Mood Disorders; Patient Dropouts; Retrospect

2023
Prevalence and clinical presentation of HIV positive female psychiatric inpatients.
    African journal of psychiatry, 2013, Volume: 16, Issue:1

    Topics: Adult; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Comorbidity; Cross-Sectional Studie

2013
Cobalamin deficiency manifested with seizures, mood oscillations, psychotic features and reversible dementia in the absence of typical neurologic and hematologic signs and symptoms: a case report.
    Collegium antropologicum, 2013, Volume: 37, Issue:1

    Topics: Carbamazepine; Dementia; Diazepam; Electroencephalography; Haloperidol; Hematology; Humans; Hydroxoc

2013
Attitudes of patients and family members towards implantable psychiatric medication.
    Schizophrenia research, 2008, Volume: 105, Issue:1-3

    Topics: Adult; Attitude to Health; Clozapine; Cross-Cultural Comparison; Data Collection; Drug Implants; Fam

2008
The involvement of GABA(A) receptor in the molecular mechanisms of combined selective serotonin reuptake inhibitor-antipsychotic treatment.
    The international journal of neuropsychopharmacology, 2011, Volume: 14, Issue:2

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Cells, Cultured; Clozapine; Dopamine; Drug The

2011
Retinoid x receptor gamma control of affective behaviors involves dopaminergic signaling in mice.
    Neuron, 2010, Jun-24, Volume: 66, Issue:6

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Cell Count; Dependovirus; Disease Models, Animal;

2010
An unusual presentation of a varicella zoster virus encephalitis in a patient treated for metastatic prostate cancer.
    Journal of the American Geriatrics Society, 2010, Volume: 58, Issue:12

    Topics: Acyclovir; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Antipsychotic Agents;

2010
Parasites as causative agents of human affective disorders? The impact of anti-psychotic, mood-stabilizer and anti-parasite medication on Toxoplasma gondii's ability to alter host behaviour.
    Proceedings. Biological sciences, 2006, Apr-22, Volume: 273, Issue:1589

    Topics: Animals; Antimanic Agents; Antiprotozoal Agents; Antipsychotic Agents; Behavior, Animal; Cats; Dapso

2006
Anabolic androgenic steroid abuse and mood disorder: a case report.
    The international journal of neuropsychopharmacology, 2007, Volume: 10, Issue:2

    Topics: Adult; Anabolic Agents; Antipsychotic Agents; Bipolar Disorder; Haloperidol; Humans; Impulsive Behav

2007
Lithium/haloperidol combinations and brain damage.
    Lancet (London, England), 1982, Mar-13, Volume: 1, Issue:8272

    Topics: Brain; Drug Therapy, Combination; Haloperidol; Humans; Lithium; Mental Disorders; Middle Aged; Mood

1982
Rapid tranquilization of disturbed patients.
    Journal of the Medical Association of the State of Alabama, 1982, Volume: 51, Issue:11

    Topics: Antipsychotic Agents; Haloperidol; Humans; Mood Disorders; Phenothiazines

1982
beta-Endorphin and beta-lipotropin plasma levels in chronic schizophrenia, primary affective disorders and secondary affective disorders.
    Psychoneuroendocrinology, 1981, Volume: 6, Issue:4

    Topics: Adrenocorticotropic Hormone; Adult; beta-Endorphin; beta-Lipotropin; Chronic Disease; Endorphins; Fe

1981
Receptor techniques in the study of plasma levels of neuroleptics and antidepressant drugs.
    Communications in psychopharmacology, 1980, Volume: 4, Issue:6

    Topics: Chromatography, Gas; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Haloperidol; Humans

1980
Neurologic side effects in neuroleptic-naive patients treated with haloperidol or risperidone.
    Neurology, 1999, Mar-10, Volume: 52, Issue:4

    Topics: Adult; Female; Haloperidol; Humans; Male; Middle Aged; Mood Disorders; Prospective Studies; Risperid

1999
Effects of chronic treatment with trihexyphenidyl and carbamazepine alone or in combination with haloperidol on substance P content in rat brain: a possible implication of substance P in affective disorders.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:3

    Topics: Animals; Body Weight; Brain Chemistry; Carbamazepine; Dopamine; Dose-Response Relationship, Drug; ga

1988