haloperidol has been researched along with Acute Respiratory Distress Syndrome in 7 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We discus the case of a forty-nine year old patient with haloperidol induced laryngeal dystonia (LD)." | 7.74 | A patient with haloperidol induced laryngeal dystonia. ( Peek, DF, 2008) |
| "We discus the case of a forty-nine year old patient with haloperidol induced laryngeal dystonia (LD)." | 3.74 | A patient with haloperidol induced laryngeal dystonia. ( Peek, DF, 2008) |
| "Epichlorohydrin is an organochlorine compound and a epoxide." | 1.72 | Clinical Profile of Patients with Acute Epichlorohydrin Poisoning - An Observational Study. ( Kothari, S; Majumder, B; Sahay, R, 2022) |
| "We observed a case of NMS in which disseminated intravascular coagulation was a prominent feature." | 1.27 | Neuroleptic malignant syndrome complicated by disseminated intravascular coagulation. ( DiPette, DJ; Eles, GR; Songer, JE, 1984) |
| "ARDS and disseminated intravascular coagulation may be important, atypical signs encountered early in NMS and complicating its recognition." | 1.27 | Neuroleptic malignant syndrome presenting as adult respiratory distress syndrome and disseminated intravascular coagulation. ( Baxter, JW; Johnson, MD; Newman, JH, 1988) |
| "It has been suggested that acute respiratory distress syndrome (ARDS) is induced by a cybernetic imbalance of the central nervous system secondary to alarm reaction-provoked intravascular coagulation into cerebral microvessels." | 1.27 | Acute respiratory distress syndrome (ARDS): the prophylactic effect of neurodepressant agents. ( de Oliveira Antonio, MP; de Oliveira, GG; Shimano, LT, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Peek, DF | 1 |
| Yagmur, F | 1 |
| Ulusoy, HB | 1 |
| Buyukoglan, H | 1 |
| Kaya, MG | 1 |
| Eles, GR | 1 |
| Songer, JE | 1 |
| DiPette, DJ | 1 |
| Cammarano, WB | 1 |
| Pittet, JF | 1 |
| Weitz, S | 1 |
| Schlobohm, RM | 1 |
| Marks, JD | 1 |
| Johnson, MD | 1 |
| Newman, JH | 1 |
| Baxter, JW | 1 |
| de Oliveira, GG | 1 |
| Shimano, LT | 1 |
| de Oliveira Antonio, MP | 1 |
| Majumder, B | 1 |
| Sahay, R | 1 |
| Kothari, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Opioids Withdrawal Syndrome in Critically Ill Patients: a Multicenter Prospective Cohort Study[NCT02318290] | 54 participants (Actual) | Observational | 2015-01-31 | Completed | |||
| Opioid Withdrawal Symptoms in Critically Ill Patients[NCT03374722] | 55 participants (Actual) | Observational | 2018-01-01 | Completed | |||
| Signs and Symptoms of Opioid-associated Iatrogenic Withdrawal in Critically Ill Adults[NCT03435614] | 29 participants (Actual) | Observational | 2018-02-26 | Completed | |||
| Assessing Current Analgesia and Sedation Weaning Practices in Adult Critically Ill Patients[NCT04422808] | 2,437 participants (Actual) | Observational | 2021-06-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Percentage of daily assessments associated with each of the following signs and symptoms experienced by patients with and without OIWS (Restlessness (Richmond Agitation-Sedation scale = 1), Agitation (RASS > 1), Anxiety, Hallucinations, Insomnia/sleep disturbance (< 4 hours of continuous sleep), Mydriasis (Pupil diameter > 2 mm) and systolic blood pressure (SBP) > 140 mmHg. These assessments were performed once daily.~Note that for the group of patients experiencing IWS, the data on signs and symptoms are limited to the assessment on the day that patients experienced OIWS.~The signs and symptoms presented (Restlessness; Agitation; Anxiety, Hallucinations, Insomnia/sleep disturbance; mydriasis; SBP > 140) were selected based on a > 15 % absolute difference between both groups which was judged to be clinically significant." (NCT03435614)
Timeframe: From first day of opioid dose reduction until transfer out of Intensive care unit (ICU) or a maximum of 14 days, including one further assessment post-ICU transfer
| Intervention | percentage of assessments (Number) | ||||||
|---|---|---|---|---|---|---|---|
| Restlessness (RASS = 1) | Agitation (RASS > 1) | Anxiety | Hallucinations | Insomnia/Sleep disturbance (< 4 hours of continuous sleep) | Mydriasis (pupil size > 2mm) | Systolic Blood Pressure (SBP) > 140 mmHg | |
| IWS Negative | 13.6 | 4.9 | 30.6 | 11.2 | 21.4 | 77.8 | 53 |
| IWS Positive | 28.6 | 28.6 | 57.1 | 28.6 | 66.7 | 100 | 85.7 |
7 other studies available for haloperidol and Acute Respiratory Distress Syndrome
| Article | Year |
|---|---|
A patient with haloperidol induced laryngeal dystonia.
Topics: Antipsychotic Agents; Dystonia; Haloperidol; Humans; Laryngeal Diseases; Male; Middle Aged; Respirat | 2008 |
Acute respiratory distress due to antipsychotic drugs.
Topics: Adult; Antiparkinson Agents; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Drug Therapy, Co | 2010 |
Neuroleptic malignant syndrome complicated by disseminated intravascular coagulation.
Topics: Adult; Autonomic Nervous System Diseases; Basal Ganglia Diseases; Disseminated Intravascular Coagula | 1984 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Neuroleptic malignant syndrome presenting as adult respiratory distress syndrome and disseminated intravascular coagulation.
Topics: Diagnosis, Differential; Disseminated Intravascular Coagulation; Haloperidol; Humans; Male; Middle A | 1988 |
Acute respiratory distress syndrome (ARDS): the prophylactic effect of neurodepressant agents.
Topics: Animals; Burns; Central Nervous System Depressants; Chlorpromazine; Diazepam; Dogs; Haloperidol; Hum | 1986 |
Clinical Profile of Patients with Acute Epichlorohydrin Poisoning - An Observational Study.
Topics: Adolescent; Epichlorohydrin; Epoxy Resins; Glycerol; Humans; Pleural Effusion; Respiratory Distress | 2022 |