haloperidol has been researched along with Abnormalities, Drug-Induced in 15 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the safety of the butyrophenone neuroleptics haloperidol and penfluridol in pregnancy." | 9.11 | Safety of haloperidol and penfluridol in pregnancy: a multicenter, prospective, controlled study. ( Arnon, J; Clementi, M; Diav-Citrin, O; Garbis, H; Ornoy, A; Ornoy, S; Schaefer, C; Shechtman, S, 2005) |
| "To assess the safety of the butyrophenone neuroleptics haloperidol and penfluridol in pregnancy." | 5.11 | Safety of haloperidol and penfluridol in pregnancy: a multicenter, prospective, controlled study. ( Arnon, J; Clementi, M; Diav-Citrin, O; Garbis, H; Ornoy, A; Ornoy, S; Schaefer, C; Shechtman, S, 2005) |
| "A second case of severe limb malformations was observed following maternal use of haloperidol early in the first trimester of pregnancy." | 3.65 | Limb malformations following maternal use of haloperidol. ( Heggeness, L; McCullar, FW, 1975) |
| "Treatment of bromperidol caused sedation of pregnant females in 1." | 1.27 | [Teratogenicity study on bromperidol in rats]. ( Huang, KJ; Imai, S; Sudo, T; Takeshima, T; Tauchi, K, 1984) |
| " A dose-response relationship was evident as 80-245 mg/kg produced from 3 to 70% fetal anomalies." | 1.26 | Haloperidol teratogenicity in the fetal hamster. ( Geber, WF; Gill, TS; Guram, MS, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (86.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diav-Citrin, O | 1 |
| Shechtman, S | 1 |
| Ornoy, S | 1 |
| Arnon, J | 1 |
| Schaefer, C | 1 |
| Garbis, H | 1 |
| Clementi, M | 1 |
| Ornoy, A | 1 |
| Nurnberg, HG | 1 |
| Imai, S | 1 |
| Tauchi, K | 1 |
| Huang, KJ | 1 |
| Takeshima, T | 1 |
| Sudo, T | 1 |
| Gill, TS | 1 |
| Guram, MS | 1 |
| Geber, WF | 1 |
| Iqbal, MM | 1 |
| Gundlapalli, SP | 1 |
| Ryan, WG | 1 |
| Ryals, T | 1 |
| Passman, TE | 1 |
| Rise, A | 1 |
| Hanson, JW | 1 |
| Oakley, GP | 1 |
| McCullar, FW | 1 |
| Heggeness, L | 1 |
| Archer, JD | 1 |
| Piccione, E | 1 |
| Ticconi, C | 1 |
| Cennamo, M | 1 |
| Szabo, KT | 1 |
| Brent, RL | 1 |
| Vichi, F | 2 |
| Pierleoni, P | 1 |
| Bertelli, A | 1 |
| Polani, PE | 1 |
| Spector, R | 1 |
| Seller, MJ | 1 |
| Tuchmann-Duplessis, H | 1 |
| Mercier-Parot, L | 1 |
| Krechkovskiĭ, EA | 1 |
| Anisimova, IG | 1 |
| Vislova, SV | 1 |
| Zaprivoda, LP | 1 |
| Zhuchkova, NV | 1 |
3 reviews available for haloperidol and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Effects of antimanic mood-stabilizing drugs on fetuses, neonates, and nursing infants.
Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Antimanic Agents; Benzodiazepines; Breast Feed | 2001 |
[Problems of neurological drug therapy in pregnancy].
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Antiparkinson Agents; Carbamazepine; Chelating Agents; | 1989 |
[Neuroleptics in experimental teratogenesis].
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Chlorpromazine; Fluphenazine; Haloperidol; Mice; | 1968 |
1 trial available for haloperidol and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Safety of haloperidol and penfluridol in pregnancy: a multicenter, prospective, controlled study.
Topics: Abnormalities, Drug-Induced; Adult; Antipsychotic Agents; Birth Weight; Butyrophenones; Cohort Studi | 2005 |
11 other studies available for haloperidol and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Treatment of mania in the last six months of pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Antipsychotic Agents; Bipolar Disorder; Female; Haloperidol; Hum | 1980 |
[Teratogenicity study on bromperidol in rats].
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Antipsychotic Agents; Behavior, Animal; Body | 1984 |
Haloperidol teratogenicity in the fetal hamster.
Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Female; Fetal Resorption; Food Deprivation; Halope | 1982 |
[Neuroleptics].
Topics: Abnormalities, Drug-Induced; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Female; Fluphenaz | 1976 |
Letter: Haloperidol and limb deformity.
Topics: Abnormalities, Drug-Induced; Female; Haloperidol; Humans; Infant, Newborn; Limb Deformities, Congeni | 1975 |
Limb malformations following maternal use of haloperidol.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Drug Therapy, Combination; Female; Fetus; Halo | 1975 |
Editorial: Another possible teratogen?
Topics: Abnormalities, Drug-Induced; Female; Haloperidol; Humans; Infant, Newborn; Limb Deformities, Congeni | 1975 |
Letter: Species differences in experimental teratogenesis by tranquillising agents.
Topics: Abnormalities, Drug-Induced; Animals; Antipsychotic Agents; Cleft Palate; Dose-Response Relationship | 1974 |
[Lethal and teratogenic effects of haloperidol in mouse embryos].
Topics: Abnormalities, Drug-Induced; Animals; Anophthalmos; Brain; Cleft Lip; Cleft Palate; Embryo, Mammalia | 1970 |
[Effect of a neuroleptic, haloperidol, on the gestation and prenatal development of rodents. Results of 3 groups of experiments].
Topics: Abnormalities, Drug-Induced; Animals; Embryonic and Fetal Development; Female; Fetus; Haloperidol; H | 1968 |
[Experimental study of the delayed effects on the generative function of cresyl glycidyl ether].
Topics: Abnormalities, Drug-Induced; Air Pollutants, Occupational; Animals; Embryo, Mammalian; Epoxy Resins; | 1985 |