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haloperidol and Abnormalities, Autosome

haloperidol has been researched along with Abnormalities, Autosome in 19 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Research Excerpts

ExcerptRelevanceReference
"Haloperidol (HLP) is a potent antipsychotic drug that is commonly used for the treatments of schizophrenia and bipolar disorders but has a tendency to cause adverse effects."1.40Evaluation of the in vitro cytogenotoxicity profile of antipsychotic drug haloperidol using human peripheral blood lymphocytes. ( Gajski, G; Garaj-Vrhovac, V; Gerić, M, 2014)
" AH Plus was also shown to be toxic in concentrations of 16."1.32Examination of cytotoxicity and mutagenicity of AH26 and AH Plus sealers. ( Anić, I; Garaj-Vrhovac, V; Jukić, S; Miletić, I; Osmak, M; Zeljezić, D, 2003)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199015 (78.95)18.7374
1990's2 (10.53)18.2507
2000's1 (5.26)29.6817
2010's1 (5.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gajski, G1
Gerić, M1
Garaj-Vrhovac, V2
Ahuja, YR1
Jaju, M1
Saxena, R1
Reddy, PV1
Subramanyam, S1
Rapoport, IA1
Filippova, LM1
Zhurkov, VS1
van den Berghe, H1
Wagner, M1
Miletić, I1
Jukić, S1
Anić, I1
Zeljezić, D1
Osmak, M1
Suskov, II3
Sazonova, LA3
Hedner, K3
Högstedt, B2
Kolnig, AM2
Mark-Vendel, E2
Strömbeck, B2
Mitelman, F3
Ehrenberg, L1
Hussain, S1
Fregert, S1
Hillbertz-Nilsson, K1
Talakin, IuN1
Chernykh, LV2
Zholos, VV1
Otroshchenko, NM1
Savchenko, MV1
Nekrasova, IA1
Ivanova, LA1
Krishtopa, VI2
Frolov, AK1
de Jong, G1
van Sittert, NJ1
Natarajan, AT1
Dabney, BJ1
Swietlińska, Z1
Zuk, J1
Korzeń, M1
Zbrzeska, J1

Reviews

1 review available for haloperidol and Abnormalities, Autosome

ArticleYear
Genetic toxicity of some important epoxides.
    Mutation research, 1981, Volume: 86, Issue:1

    Topics: Animals; Carcinogens; Chemical Phenomena; Chemistry; Chromosome Aberrations; Crossing Over, Genetic;

1981

Trials

1 trial available for haloperidol and Abnormalities, Autosome

ArticleYear
Clastogenic effects of haloperidol in vivo and of haloperidol, droperidol, and pipamperone in vitro. A negative study.
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:12

    Topics: Adult; Aged; Butyrophenones; Chromosome Aberrations; Clinical Trials as Topic; Culture Media; Droper

1974

Other Studies

17 other studies available for haloperidol and Abnormalities, Autosome

ArticleYear
Evaluation of the in vitro cytogenotoxicity profile of antipsychotic drug haloperidol using human peripheral blood lymphocytes.
    Environmental toxicology and pharmacology, 2014, Volume: 38, Issue:1

    Topics: Antipsychotic Agents; Apoptosis; Cell Survival; Chromosome Aberrations; Comet Assay; Cytostatic Agen

2014
Cytogenetic effects of psychotropic drug haloperidol on human lymphocytes.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:6

    Topics: Adult; Cells, Cultured; Chromosome Aberrations; Chromosomes; Haloperidol; Humans; Lymphocytes; Time

1984
Action of haloperidol on mitoses in Allium cepa.
    Indian journal of experimental biology, 1976, Volume: 14, Issue:5

    Topics: Chromosome Aberrations; Haloperidol; Mitosis; Plant Cells

1976
Investigation of the mutagenic activity of phenothiazines and other drug preparations.
    Soviet genetics, 1973, Dec-01, Volume: 7, Issue:8

    Topics: Animals; Caffeine; Chromosome Aberrations; Drosophila melanogaster; Gene Frequency; Genes, Lethal; H

1973
[Effect of some common piperidine derivatives on human chromosomes in vitro].
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:7

    Topics: Benperidol; Chemical Phenomena; Chemistry; Chromosome Aberrations; Chromosome Disorders; Chromosomes

1971
Examination of cytotoxicity and mutagenicity of AH26 and AH Plus sealers.
    International endodontic journal, 2003, Volume: 36, Issue:5

    Topics: Animals; Bismuth; Cell Line; Cell Survival; Chromosome Aberrations; Cricetinae; Cricetulus; Dimethyl

2003
[Human cytogenetic affects in relation to sex, age and the duration of contract with a chemical mutagen].
    Doklady Akademii nauk SSSR, 1983, Volume: 273, Issue:6

    Topics: Adult; Aging; Chromosome Aberrations; Environmental Exposure; Epoxy Resins; Female; Humans; Lymphocy

1983
Sister chromatid exchanges and structural chromosome aberrations in relation to smoking in 91 individuals.
    Hereditas, 1983, Volume: 98, Issue:1

    Topics: Adult; Chromosome Aberrations; Crossing Over, Genetic; Epoxy Resins; Female; Humans; Male; Sister Ch

1983
Cytogenetic effects of epoxy, phenolformaldehyde and polyvinylchloride resins in man.
    Mutation research, 1982, Volume: 104, Issue:1-3

    Topics: Cells, Cultured; Chromosome Aberrations; Environmental Exposure; Epoxy Resins; Formaldehyde; Humans;

1982
Relationship between sister chromatid exchanges and structural chromosome aberrations in lymphocytes of 100 individuals.
    Hereditas, 1982, Volume: 97, Issue:2

    Topics: Adolescent; Adult; Aged; Alcoholism; Chromosome Aberrations; Crossing Over, Genetic; Epoxy Resins; E

1982
Occupational exposure to epoxy resins has no cytogenetic effect.
    Mutation research, 1980, Volume: 77, Issue:4

    Topics: Adolescent; Adult; Aged; Chromosome Aberrations; Environmental Exposure; Epoxy Resins; Female; Human

1980
[The toxicological hygienic evaluation of the manufacture of epoxy resins based on complex glycidyl ethers].
    Gigiena truda i professional'nye zabolevaniia, 1991, Issue:4

    Topics: Adult; Air Pollutants, Occupational; Animals; Chromosome Aberrations; Embryo Loss; Epoxy Compounds;

1991
[Cytogenetic examination of workers employed in epoxy resin production].
    Gigiena truda i professional'nye zabolevaniia, 1990, Issue:3

    Topics: Adult; Chromosome Aberrations; Epoxy Resins; Humans; Middle Aged; Occupations

1990
Cytogenetic monitoring of industrial populations potentially exposed to genotoxic chemicals and of control populations.
    Mutation research, 1988, Volume: 204, Issue:3

    Topics: Chromosome Aberrations; Cytogenetics; Epoxy Resins; Humans; Mass Screening; Mutagens; Occupational D

1988
Cytogenetic findings on employees with potential exposure to epichlorohydrin.
    Progress in clinical and biological research, 1986, Volume: 207

    Topics: Chlorohydrins; Chromatids; Chromosome Aberrations; Culture Media; Environmental Exposure; Epichloroh

1986
Cytogenetic effects of epoxy resin in man: dependence on sex, age and period of exposure.
    Mutation research, 1985, Volume: 155, Issue:3

    Topics: Adult; Age Factors; Chromosome Aberrations; Chromosomes, Human; Environmental Exposure; Epoxy Resins

1985
The effect of diepoxybutane on chromosomes of Vicia faba.
    Molecular & general genetics : MGG, 1967, Volume: 99, Issue:4

    Topics: Alkylating Agents; Chloramphenicol; Chromosome Aberrations; Edetic Acid; Epoxy Resins; Ethers, Cycli

1967