Page last updated: 2024-10-28

haloperidol and Abnormal Movements

haloperidol has been researched along with Abnormal Movements in 39 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Research Excerpts

ExcerptRelevanceReference
"Animal models of haloperidol (HAL)-induced neurotoxicity and orofacial dyskinesia (OD) have long been used to study human tardive dyskinesia (TD)."8.02Naringin Ameliorates Haloperidol-Induced Neurotoxicity and Orofacial Dyskinesia in a Rat Model of Human Tardive Dyskinesia. ( Fang, CH; Lin, YW; Soung, HS; Tseng, HC; Wang, MH; Yang, CC, 2021)
"Effect of administration of Rice bran oil (RBO) was evaluated on haloperidol elicited tardive dyskinesia in rats."7.83Report: Protective effects of rice bran oil in haloperidol-induced tardive dyskinesia and serotonergic responses in rats. ( Haleem, DJ; Haleem, MA; Samad, N, 2016)
"Tardive dyskinesia (TD) is a movement disorder that appears after chronic use of drugs that block dopaminergic receptors such as antipsychotics."5.62PPARγ receptors are involved in the effects of cannabidiol on orofacial dyskinesia and cognitive dysfunction induced by typical antipsychotic in mice. ( Guimarães, FS; Prado, DDS; Sonego, AB, 2021)
"Animal models of haloperidol (HAL)-induced neurotoxicity and orofacial dyskinesia (OD) have long been used to study human tardive dyskinesia (TD)."4.02Naringin Ameliorates Haloperidol-Induced Neurotoxicity and Orofacial Dyskinesia in a Rat Model of Human Tardive Dyskinesia. ( Fang, CH; Lin, YW; Soung, HS; Tseng, HC; Wang, MH; Yang, CC, 2021)
"Haloperidol (Hal) is an antipsychotic related to movement disorders."3.91Influence of magnesium supplementation and L-type calcium channel blocker on haloperidol-induced movement disturbances. ( Burger, ME; da Silva Barcelos, RC; Kronbauer, M; Metz, VG; Milanesi, LH; Roversi, K; Rubert Rossato, D, 2019)
"Effect of administration of Rice bran oil (RBO) was evaluated on haloperidol elicited tardive dyskinesia in rats."3.83Report: Protective effects of rice bran oil in haloperidol-induced tardive dyskinesia and serotonergic responses in rats. ( Haleem, DJ; Haleem, MA; Samad, N, 2016)
"Haloperidol treatment reduced the locomotor activity and increased the number of VCM in rats."1.72Reversal of haloperidol-induced orofacial dyskinesia and neuroinflammation by isoflavones. ( Boeck, CR; da Silva Schmitz, I; de Lima, VB; Dorneles, GP; Mezzomo, NF; Peroza, LR; Romao, PRT; Schaffer, LF, 2022)
"Tardive dyskinesia (TD) is a movement disorder that appears after chronic use of drugs that block dopaminergic receptors such as antipsychotics."1.62PPARγ receptors are involved in the effects of cannabidiol on orofacial dyskinesia and cognitive dysfunction induced by typical antipsychotic in mice. ( Guimarães, FS; Prado, DDS; Sonego, AB, 2021)
"We present a case of hemichorea/hemiballism, a rare complication of hyperglycemia."1.51[Hemichorea/hemiballism a rare complication of hyperglycemia]. ( Kataja Knight, A; Magnusson, P; Sjöholm, Å; Tidehag, L, 2019)
"Haloperidol (1 mg/kg, ip) was administered for 21 successive days to induce orofacial dyskinesia and catalepsy."1.48Protective effect of hesperetin against haloperidol-induced orofacial dyskinesia and catalepsy in rats. ( Dhingra, D; Gahalain, N; Goswami, S, 2018)
"Non-ketotic hyperglycaemic hemichorea-hemiballismus (NHHH) is commonly seen among elderly Asian women with type 2 diabetes mellitus."1.48Paediatric non-ketotic hyperglycaemic hemichorea-hemiballismus. ( Benitez, JAEL; Sacro, CAL; Suratos, CTR; Urquiza, SC, 2018)
"Mice treated with haloperidol showed an increase in microglial activation and inflammatory mediators in the striatum."1.48Cannabidiol prevents haloperidol-induced vacuos chewing movements and inflammatory changes in mice via PPARγ receptors. ( Cunha, TM; Del Bel, EA; Guimarães, FS; Prado, DS; Raisman-Vozari, R; Sepulveda-Diaz, JE; Sonego, AB; Tirapelli, CR; Vale, GT, 2018)
"The hemiballismus was significant and persistent, resulting in profound functional disability."1.46Management of Severe Hemiballismus: Treatment Challenges in the Acute Inpatient Rehabilitation Setting: A Case Presentation. ( Altschuler, EL; Brighenti, A; Hodde, M; Rowe, KE; Surapaneni, K; Terrigno, P, 2017)
"They also displayed reduced abnormal involuntary movements after apomorphine and quinpirole treatment in the mouse dyskinesia model of Parkinson's disease."1.40G-protein coupled receptor 6 deficiency alters striatal dopamine and cAMP concentrations and reduces dyskinesia in a mouse model of Parkinson's disease. ( Ferger, B; Hengerer, B; Oeckl, P, 2014)
"Although persistent involuntary movements caused by cerebrovascular diseases mostly in middle-aged patients are well known, transient involuntary movements are an unusual manifestation of cerebrovascular diseases."1.35[Case of reversible ischemic neurological deficit presented as hemiballism]. ( Ishizaka, S; Kawahara, I; Matsuo, Y; Nakamoto, M; Tokunaga, Y; Yagi, N, 2008)
"Three cases of hemichorea-hemiballismus (HC-HB) associated with nonketotic hyperglycemia were reported."1.35Hemichorea-hemiballismus associated with nonketotic hyperglycemia: a possible role of inflammation. ( Deng, BQ; Wang, JH; Wang, ZK; Wu, T; Zhang, P; Zhang, YW, 2009)
"Hemiballismus is characterized by the abrupt onset of violent proximal flinging movements, affecting the limbs, neck and trunk on one side of the body."1.32Hemiballismus following general anesthesia. A case report. ( Buraczyńska, K; Pilarczyk, M; Sagan, M; Stelmasiak, Z; Tynecka, M, 2003)
"We report eight cases of hemiballism."1.31[Hemiballism: report of eight cases]. ( Coral, P; Teive, HA; Werneck, LC, 2000)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.13)18.7374
1990's1 (2.56)18.2507
2000's15 (38.46)29.6817
2010's17 (43.59)24.3611
2020's4 (10.26)2.80

Authors

AuthorsStudies
Mezzomo, NF1
da Silva Schmitz, I1
de Lima, VB1
Dorneles, GP1
Schaffer, LF1
Boeck, CR1
Romao, PRT1
Peroza, LR1
Uslu, ET1
Mengi, M1
Beyazyüz, E1
Çelikkol, A1
Albayrak, Y1
Wang, MH2
Yang, CC1
Tseng, HC2
Fang, CH1
Lin, YW1
Soung, HS2
Sonego, AB2
Prado, DDS1
Guimarães, FS2
Dhingra, D1
Goswami, S1
Gahalain, N1
Benvegnú, DM1
Roversi, K3
Barcelos, RCS1
Trevizol, F1
Pase, CS1
Segat, HJ1
Dias, VT2
Savian, AL1
Piccoli, BL1
Piccolo, J1
Dutra-Filho, CS1
Emanuelli, T1
de Bona da Silva, C1
Beck, RCR1
Burger, ME3
Chen, CN1
Chang, KC1
Cho, HS1
Hong, CT1
Chan, L1
Suratos, CTR1
Benitez, JAEL1
Urquiza, SC1
Sacro, CAL1
Prado, DS1
Vale, GT1
Sepulveda-Diaz, JE1
Cunha, TM1
Tirapelli, CR1
Del Bel, EA1
Raisman-Vozari, R1
Xiao, F1
Liu, M1
Wang, XF1
Tidehag, L1
Kataja Knight, A1
Magnusson, P1
Sjöholm, Å1
Kronbauer, M2
Metz, VG2
Milanesi, LH1
Rubert Rossato, D1
da Silva Barcelos, RC2
Oeckl, P1
Hengerer, B1
Ferger, B1
McLay, SV1
MacDonald, SP1
Samad, N1
Haleem, MA1
Haleem, DJ1
de David Antoniazzi, CT1
Hodde, M1
Rowe, KE1
Surapaneni, K1
Terrigno, P1
Brighenti, A1
Altschuler, EL1
Lin, CJ1
Huang, P1
Kawahara, I1
Ishizaka, S1
Yagi, N1
Nakamoto, M1
Matsuo, Y1
Tokunaga, Y1
Wang, JH1
Wu, T1
Deng, BQ1
Zhang, YW1
Zhang, P1
Wang, ZK1
Marchione, P1
Vento, C1
Marianetti, M1
Romeo, T1
Amabile, GA1
Giacomini, P1
Baik, JS1
You, SJ1
Lee, MS1
Kasture, S1
Pawar, A1
Kasture, A1
Foddis, C1
Frau, MA1
Maxia, A1
Ohye, C1
Shibazaki, T1
Gupta, S1
Linn, GS1
Negi, SS1
Gerum, SV1
Javitt, DC1
VAISBERG, M1
SAUNDERS, JC1
Pilarczyk, M1
Buraczyńska, K1
Sagan, M1
Tynecka, M1
Stelmasiak, Z1
Nagai, C1
Chu, NS1
Dekundy, A1
Pietraszek, M1
Schaefer, D1
Cenci, MA1
Danysz, W1
Wehrschuetz, M1
Simbrunner, J1
Enzinger, C1
Ebner, F1
Verma, R1
Agarwal, A1
Kar, AM1
Hans, ML1
Maxwell, C1
Ehrlichman, RS1
Metzger, K1
Liang, Y1
Siegel, SJ1
Lowman, AM1
Korenyi, C1
Whittier, JR1
Oerlemans, WG1
Moll, LC1
Eichhammer, P1
Albus, M1
Borrmann-Hassenbach, M1
Schoeler, A1
Putzhammer, A1
Frick, U1
Klein, HE1
Rohrmeier, T1
Coral, P1
Teive, HA1
Werneck, LC1

Reviews

3 reviews available for haloperidol and Abnormal Movements

ArticleYear
Hemichorea after hyperglycemia correction: A case report and a short review of hyperglycemia-related hemichorea at the euglycemic state.
    Medicine, 2018, Volume: 97, Issue:10

    Topics: Aged; Anti-Dyskinesia Agents; Diagnosis, Differential; Dyskinesias; Haloperidol; Humans; Hyperglycem

2018
Safety in treating bipolar disorder.
    The Journal of family practice, 2003, Volume: Suppl

    Topics: Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Diabetes Melli

2003
[Progress in diagnosis of and therapy for diabetic choreic movement and ballismus].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2004, Aug-10, Volume: 93, Issue:8

    Topics: Anti-Dyskinesia Agents; Basal Ganglia; Chorea; Diabetes Complications; Diabetes Mellitus; Dyskinesia

2004

Other Studies

36 other studies available for haloperidol and Abnormal Movements

ArticleYear
Reversal of haloperidol-induced orofacial dyskinesia and neuroinflammation by isoflavones.
    Molecular biology reports, 2022, Volume: 49, Issue:3

    Topics: Animals; Dyskinesias; Haloperidol; Isoflavones; Male; Neuroinflammatory Diseases; Rats; Rats, Wistar

2022
The effects of sigma-1 agonist fluvoxamine on experimental induced tardive dyskinesia model in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2023, Aug-30, Volume: 126

    Topics: Animals; Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Dyskinesias; Fluvoxamine; Haloperi

2023
Naringin Ameliorates Haloperidol-Induced Neurotoxicity and Orofacial Dyskinesia in a Rat Model of Human Tardive Dyskinesia.
    Neurotoxicity research, 2021, Volume: 39, Issue:3

    Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dyskinesias; Flavanones; Haloperidol; Humans;

2021
PPARγ receptors are involved in the effects of cannabidiol on orofacial dyskinesia and cognitive dysfunction induced by typical antipsychotic in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2021, 12-20, Volume: 111

    Topics: Animals; Anti-Dyskinesia Agents; Antipsychotic Agents; Behavior, Animal; Cannabidiol; Cognitive Dysf

2021
Protective effect of hesperetin against haloperidol-induced orofacial dyskinesia and catalepsy in rats.
    Nutritional neuroscience, 2018, Volume: 21, Issue:9

    Topics: Animals; Behavior, Animal; Brain; Catalepsy; Dopamine; Dyskinesia, Drug-Induced; Dyskinesias; Glutat

2018
Effects of Fish and Grape Seed Oils as Core of Haloperidol-Loaded Nanocapsules on Oral Dyskinesia in Rats.
    Neurochemical research, 2018, Volume: 43, Issue:2

    Topics: Animals; Anti-Dyskinesia Agents; Biological Products; Cell Survival; Dyskinesias; Fish Oils; Fishes;

2018
Protective Effect of L-Theanine on Haloperidol-Induced Orofacial.
    The Chinese journal of physiology, 2018, Feb-28, Volume: 61, Issue:1

    Topics: Animals; Corpus Striatum; Disease Models, Animal; Dyskinesias; Glutamates; Haloperidol; Lipid Peroxi

2018
Paediatric non-ketotic hyperglycaemic hemichorea-hemiballismus.
    BMJ case reports, 2018, Apr-05, Volume: 2018

    Topics: Adolescent; Anti-Dyskinesia Agents; Blood Glucose; Chorea; Clonazepam; Diabetes Mellitus, Type 1; Dy

2018
Cannabidiol prevents haloperidol-induced vacuos chewing movements and inflammatory changes in mice via PPARγ receptors.
    Brain, behavior, and immunity, 2018, Volume: 74

    Topics: Animals; Antioxidants; Antipsychotic Agents; Behavior, Animal; Brain; Cannabidiol; Corpus Striatum;

2018
Involuntary choreiform movements in a diabetic patient.
    Lancet (London, England), 2019, 03-09, Volume: 393, Issue:10175

    Topics: Anti-Dyskinesia Agents; Basal Ganglia; Blood Glucose; Clonazepam; Diabetes Mellitus, Type 2; Dyskine

2019
[Hemichorea/hemiballism a rare complication of hyperglycemia].
    Lakartidningen, 2019, Mar-26, Volume: 116

    Topics: Aged, 80 and over; Anti-Dyskinesia Agents; Basal Ganglia; Chorea; Dyskinesias; Female; Haloperidol;

2019
Influence of magnesium supplementation and L-type calcium channel blocker on haloperidol-induced movement disturbances.
    Behavioural brain research, 2019, 11-18, Volume: 374

    Topics: Animals; Antipsychotic Agents; Brain; Calcium Channel Blockers; Calcium Channels, L-Type; Corpus Str

2019
G-protein coupled receptor 6 deficiency alters striatal dopamine and cAMP concentrations and reduces dyskinesia in a mouse model of Parkinson's disease.
    Experimental neurology, 2014, Volume: 257

    Topics: Adrenergic Agents; Animals; Anti-Dyskinesia Agents; Corpus Striatum; Cyclic AMP; Disease Models, Ani

2014
Hyper-dopaminergic ballismus and respiratory dyskinesia treated with intravenous haloperidol.
    Emergency medicine Australasia : EMA, 2014, Volume: 26, Issue:6

    Topics: Anti-Dyskinesia Agents; Antiparkinson Agents; Dopamine Agents; Dyskinesias; Haloperidol; Humans; Inj

2014
Report: Protective effects of rice bran oil in haloperidol-induced tardive dyskinesia and serotonergic responses in rats.
    Pakistan journal of pharmaceutical sciences, 2016, Volume: 29, Issue:4 Suppl

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Dyskinesias; Haloperidol; Hyd

2016
Influence of magnesium supplementation on movement side effects related to typical antipsychotic treatment in rats.
    Behavioural brain research, 2017, 03-01, Volume: 320

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Brain; Catalepsy; Chick Embryo; Disease Models,

2017
Management of Severe Hemiballismus: Treatment Challenges in the Acute Inpatient Rehabilitation Setting: A Case Presentation.
    PM & R : the journal of injury, function, and rehabilitation, 2017, Volume: 9, Issue:7

    Topics: Combined Modality Therapy; Dyskinesias; Follow-Up Studies; Haloperidol; Humans; Inpatients; Male; Mi

2017
Delayed onset diabetic striatopathy: Hemichorea-hemiballism one month after a hyperglycemic episode.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:7

    Topics: Aged; Anti-Dyskinesia Agents; Anticonvulsants; Clonazepam; Diabetes Complications; Diagnosis, Differ

2017
[Case of reversible ischemic neurological deficit presented as hemiballism].
    No shinkei geka. Neurological surgery, 2008, Volume: 36, Issue:12

    Topics: Aged; Chlorpromazine; Diagnostic Imaging; Dyskinesias; Haloperidol; Humans; Ischemic Attack, Transie

2008
Hemichorea-hemiballismus associated with nonketotic hyperglycemia: a possible role of inflammation.
    Journal of the neurological sciences, 2009, Sep-15, Volume: 284, Issue:1-2

    Topics: Aged, 80 and over; Anti-Dyskinesia Agents; Autoimmune Diseases of the Nervous System; Chorea; Corpus

2009
Hemiballismus in subthalamic haemorrhage: efficacy of levetiracetam.
    European journal of neurology, 2009, Volume: 16, Issue:6

    Topics: Aged; Anti-Dyskinesia Agents; Anticonvulsants; Antihypertensive Agents; Ataxia; Cerebellum; Dose-Res

2009
Bilateral ballism after herpes encephalitis with thalamic lesion.
    Parkinsonism & related disorders, 2010, Volume: 16, Issue:4

    Topics: Acyclovir; Adrenal Cortex Hormones; Anti-Dyskinesia Agents; Antiviral Agents; Brain; Child, Preschoo

2010
Effect of ethanolic extract of Rubia peregrina L. (Rubiaceae) on monoamine-mediated behaviour.
    Natural product research, 2011, Volume: 25, Issue:20

    Topics: Adrenergic Agents; Animals; Catalepsy; Dopamine Agents; Dyskinesias; Haloperidol; Lithium Compounds;

2011
Lesioning the thalamus for dyskinesia.
    Stereotactic and functional neurosurgery, 2001, Volume: 77, Issue:1-4

    Topics: Antiparkinson Agents; Antipsychotic Agents; Dyskinesia, Drug-Induced; Dyskinesias; Electrocoagulatio

2001
Reversal of phencyclidine-induced prepulse inhibition deficits by clozapine in monkeys.
    Psychopharmacology, 2003, Volume: 169, Issue:3-4

    Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Behavior, Animal; Cebus; Clozapine; Disease Mod

2003
TREATMENT OF DYSKINESIAS INCLUDING HUNTINGTON'S CHOREA WITH THIOPROPAZATE AND R-1625.
    Diseases of the nervous system, 1963, Volume: 24

    Topics: Chorea; Dyskinesias; Haloperidol; Humans; Huntington Disease; Movement Disorders; Phenothiazines; Tr

1963
Hemiballismus following general anesthesia. A case report.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2003, Volume: 24, Issue:4

    Topics: Anesthesia, General; Anticonvulsants; Antipsychotic Agents; Brain Ischemia; Clonazepam; Dyskinesias;

2003
Orolingual dyskinesia in central pontine myelinolysis.
    Acta neurologica Taiwanica, 2004, Volume: 13, Issue:3

    Topics: Anti-Dyskinesia Agents; Brain; Diabetes Complications; Dyskinesias; Female; Haloperidol; Humans; Lip

2004
Effects of group I metabotropic glutamate receptors blockade in experimental models of Parkinson's disease.
    Brain research bulletin, 2006, Apr-14, Volume: 69, Issue:3

    Topics: Analysis of Variance; Animals; Antiparkinson Agents; Behavior, Animal; Catalepsy; Disease Models, An

2006
[Hemiballism-hemichorea syndrome].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2007, Volume: 179, Issue:1

    Topics: Anti-Dyskinesia Agents; Brain Diseases; Cerebrovascular Circulation; Chorea; Drug Therapy, Combinati

2007
Hemichorea resulting from single enhancing computed tomography lesion.
    The Journal of the Association of Physicians of India, 2006, Volume: 54

    Topics: Albendazole; Anti-Dyskinesia Agents; Anticestodal Agents; Child; Chorea; Dyskinesias; Female; Follow

2006
Evaluation of in vitro release and in vivo efficacy of mPEG-PLA-haloperidol conjugate micelle-like structures.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2007, Volume: 83, Issue:2

    Topics: Animals; Anti-Dyskinesia Agents; Delayed-Action Preparations; Drug Delivery Systems; Dyskinesia, Dru

2007
Dyskinesia analysis. Histogram analysis of cineseismograms of human dyskinesia.
    Diseases of the nervous system, 1974, Volume: 35, Issue:4

    Topics: Aged; Anti-Dyskinesia Agents; Dyskinesias; Haloperidol; Humans; Huntington Disease; Male; Mesoridazi

1974
Non-ketotic hyperglycemia in a young woman, presenting as hemiballism-hemichorea.
    Acta neurologica Scandinavica, 1999, Volume: 100, Issue:6

    Topics: Acute Disease; Adult; Anti-Dyskinesia Agents; Brain; Chorea; Diagnosis, Differential; Dyskinesias; F

1999
Association of dopamine D3-receptor gene variants with neuroleptic induced akathisia in schizophrenic patients: a generalization of Steen's study on DRD3 and tardive dyskinesia.
    American journal of medical genetics, 2000, Apr-03, Volume: 96, Issue:2

    Topics: Acute Disease; Akathisia, Drug-Induced; Amino Acid Substitution; Antipsychotic Agents; Dyskinesias;

2000
[Hemiballism: report of eight cases].
    Arquivos de neuro-psiquiatria, 2000, Volume: 58, Issue:3A

    Topics: Adolescent; Adult; Aged; Anti-Dyskinesia Agents; Diabetes Complications; Dyskinesias; Female; Halope

2000