halometasone and Dermatitis--Seborrheic

In an open non-comparative trial 247 eczema patients were treated with Sicorten topicals. Sicorten cream yielded good to very good results in 90%, 97% and 100% of the patients suffering from atopic dermatitis, contact dermatitis and seborrhoeic dermatitis, respectively, while Sicorten ointment produced similar results in 97% and 100% of the patients with chronic atopic dermatitis and chronic contact dermatitis, respectively. In a double-blind trial involving 108 patients suffering from atopic, seborrhoeic or contact dermatitis, the therapeutic effect of Sicorten and Betnelan creams and ointments was not significantly different.

Topics: Administration, Topical; Adult; Betamethasone; Betamethasone Valerate; Child; Clinical Trials as Topic; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Seborrheic; Double-Blind Method; Humans; Ointments

C 48.401-Ba cream, containing 0.05% halomethasone was compared in a double-blind between-patients trial with a cream containing 0.1% betamethasone valerate in forty-eight patients suffering from atopic dermatitis and in thirty-nine patients suffering from seborrhoeic dermatitis. A similar comparison was made with ointments containing the same concentration of active ingredient in forty-six patients suffering from atopic dermatitis. Both ointments were also compared in a within-patient double-blind trial in thirty patients suffering from psoriasis. The analysis of the results showed that for the treatment of the above-mentioned dermatoses, both drugs, the cream as well as the ointment, are equally effective and well tolerated.

Topics: Administration, Topical; Anti-Inflammatory Agents; Betamethasone; Betamethasone Valerate; Clinical Trials as Topic; Dermatitis, Atopic; Dermatitis, Seborrheic; Double-Blind Method; Humans; Psoriasis