Page last updated: 2024-08-24

halofuginone and Graft-Versus-Host Disease

halofuginone has been researched along with Graft-Versus-Host Disease in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, W; Cheng, H; Pan, B; Song, G; Sun, Y; Wu, Y; Xu, K; Zeng, L; Zhang, Y1
Bian, YP; Cheng, H; Pan, B; Song, GL; Xia, DD; Xu, KL; Yao, Y; Zeng, LY1
Chen, W; Cheng, H; Li, Z; Pan, B; Song, G; Tian, J; Xu, K; Zeng, L2
Nagler, A; Pines, M; Snyder, D; Yarkoni, S1
Knopov, V; Levi-Schaffer, F; Nagler, A; Pines, M; Slavin, S1
Genina, O; Halevy, O; Levi-Schaffer, F; Nagler, A; Pines, M1
Nagler, A; Pines, M1

Reviews

1 review(s) available for halofuginone and Graft-Versus-Host Disease

ArticleYear
Halofuginone to treat fibrosis in chronic graft-versus-host disease and scleroderma.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2003, Volume: 9, Issue:7

    Topics: Administration, Cutaneous; Animals; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Collagen Type I; Fibrosis; Graft vs Host Disease; Humans; Mice; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Scleroderma, Systemic

2003

Other Studies

7 other study(ies) available for halofuginone and Graft-Versus-Host Disease

ArticleYear
Deviated balance between Th1 and Th17 cells exacerbates acute graft-versus-host disease in mice.
    Cytokine, 2014, Volume: 68, Issue:2

    Topics: Acute Disease; Animals; Disease Progression; Graft vs Host Disease; Interferon-gamma; Interleukin-17; Lymphocyte Count; Mice, Inbred BALB C; Mice, Inbred C57BL; Organ Specificity; Piperidines; Quinazolinones; Th1 Cells; Th17 Cells

2014
[Significance of Th1/Th17 Imbalance in Mice with Acute Graft-versus-Host Disease].
    Zhongguo shi yan xue ye xue za zhi, 2015, Volume: 23, Issue:5

    Topics: Animals; Disease Models, Animal; Graft vs Host Disease; Interferon-gamma; Interleukin-17; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Piperidines; Quinazolinones; Th1 Cells; Th17 Cells

2015
TH17 cells are critical for skin-specific pathological injury in acute graft-versus-host disease.
    Transplantation proceedings, 2012, Volume: 44, Issue:5

    Topics: Acute Disease; Animals; Bone Marrow Transplantation; Cell Differentiation; Cell Separation; Cells, Cultured; Disease Models, Animal; Female; Flow Cytometry; Graft vs Host Disease; Inflammation Mediators; Interleukin-17; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Piperidines; Quinazolinones; Skin; Th1 Cells; Th17 Cells; Time Factors

2012
Halofugine prevents cutaneous graft versus host disease by suppression of Th17 differentiation.
    Hematology (Amsterdam, Netherlands), 2012, Volume: 17, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Bone Marrow Transplantation; Cell Differentiation; Chronic Disease; Cytokines; Female; Graft vs Host Disease; Male; Mice; Mice, Inbred BALB C; Piperidines; Quinazolinones; Skin Diseases; Th17 Cells; Time Factors; Transplantation, Homologous

2012
Inhibition of collagen synthesis and changes in skin morphology in murine graft-versus-host disease and tight skin mice: effect of halofuginone.
    The Journal of investigative dermatology, 1996, Volume: 106, Issue:1

    Topics: Animals; Collagen; Disease Models, Animal; Fibrosis; Graft vs Host Disease; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Osmolar Concentration; Piperidines; Quinazolines; Quinazolinones; Scleroderma, Localized; Skin

1996
Inhibition of collagen type I synthesis by skin fibroblasts of graft versus host disease and scleroderma patients: effect of halofuginone.
    Biochemical pharmacology, 1996, Oct-11, Volume: 52, Issue:7

    Topics: Adult; Coccidiostats; Collagen; Dose-Response Relationship, Drug; Female; Fibroblasts; Graft vs Host Disease; Humans; Middle Aged; Piperidines; Quinazolines; Quinazolinones; Time Factors

1996
Topical treatment of cutaneous chronic graft versus host disease with halofuginone: a novel inhibitor of collagen type I synthesis.
    Transplantation, 1999, Dec-15, Volume: 68, Issue:11

    Topics: Administration, Topical; Adult; Animals; Collagen; Gene Expression; Graft vs Host Disease; Humans; Male; Neck; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rabbits; Range of Motion, Articular; Sclerosis; Skin; Skin Transplantation

1999