halofuginone has been researched along with Disease Exacerbation in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baek, SY; Cho, ML; Kim, HY; Kim, SM; Kwok, SK; Lee, DG; Lee, J; Lim, MA; Park, EM; Park, JS; Park, MK; Park, SH; Woo, JW; Yang, EJ | 1 |
| Chen, W; Cheng, H; Pan, B; Song, G; Sun, Y; Wu, Y; Xu, K; Zeng, L; Zhang, Y | 1 |
| Amiaud, J; Brion, R; Heymann, D; Lamora, A; Mullard, M; Redini, F; Verrecchia, F | 1 |
| Bian, Q; Cao, X; Crane, J; Cui, Z; Ding, S; Jin, X; Li, C; Qiu, T; Wan, M; Wang, L; Xie, H; Xie, L; Xie, M; Yu, B; Zhen, G | 1 |
| Chirgwin, JM; Davis, HW; Fournier, PG; Guise, TA; Javelaud, D; Juárez, P; Mauviel, A; McKenna, RC; Mohammad, KS; Niewolna, M; Peng, XH; Yin, JJ | 1 |
| Dafni, H; Gross, DJ; Nagler, A; Neeman, M; Pines, M; Reibstein, I; Slavin, S; Weiss, L | 1 |
| Fridman, E; Genina, O; Mor, Y; Nagler, A; Pines, M; Pinthus, JH; Sheffer, Y | 1 |
| Bilu, G; Bruck, R; Genina, O; Gnainsky, Y; Hagai, Y; Kawada, N; Kushnirsky, Z; Libermann, TA; Nagler, A; Pines, M; Reinhardt, DP; Spira, G; Volpin, H; Yoshizato, K | 1 |
| Barak, V; Eshhar, Z; Gavish, Z; Nagler, A; Pines, M; Pinthus, JH; Ramon, J | 1 |
9 other study(ies) available for halofuginone and Disease Exacerbation
| Article | Year |
|---|---|
Halofuginone ameliorates autoimmune arthritis in mice by regulating the balance between Th17 and Treg cells and inhibiting osteoclastogenesis.
Topics: Animals; Arthritis; Autoimmune Diseases; Cell Differentiation; Disease Models, Animal; Disease Progression; Forkhead Transcription Factors; Male; Mice; Mice, Inbred DBA; Mice, Knockout; NFATC Transcription Factors; Osteoclasts; Osteoprotegerin; Piperidines; Protein Synthesis Inhibitors; Quinazolinones; Signal Transduction; STAT3 Transcription Factor; T-Lymphocytes, Regulatory; Th17 Cells | 2014 |
Deviated balance between Th1 and Th17 cells exacerbates acute graft-versus-host disease in mice.
Topics: Acute Disease; Animals; Disease Progression; Graft vs Host Disease; Interferon-gamma; Interleukin-17; Lymphocyte Count; Mice, Inbred BALB C; Mice, Inbred C57BL; Organ Specificity; Piperidines; Quinazolinones; Th1 Cells; Th17 Cells | 2014 |
Anticancer activity of halofuginone in a preclinical model of osteosarcoma: inhibition of tumor growth and lung metastases.
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Bone Remodeling; Cell Line, Tumor; Cell Proliferation; Disease Progression; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Osteosarcoma; Piperidines; Quinazolinones; Signal Transduction; Transfection | 2015 |
Halofuginone attenuates osteoarthritis by inhibition of TGF-β activity and H-type vessel formation in subchondral bone.
Topics: Animals; Anterior Cruciate Ligament; Bone and Bones; Bone Remodeling; Bone Resorption; Cartilage, Articular; Disease Models, Animal; Disease Progression; Male; Mice; Mice, Inbred C57BL; Osteoarthritis; Osteoclasts; Piperidines; Quinazolinones; Random Allocation; Rats; Rats, Inbred Lew; Transforming Growth Factor beta | 2016 |
Halofuginone inhibits the establishment and progression of melanoma bone metastases.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Growth Processes; Cell Line, Tumor; Disease Progression; Female; Gene Expression; Humans; Melanoma; Mice; Mice, Nude; Piperidines; Quinazolinones; Signal Transduction; Xenograft Model Antitumor Assays | 2012 |
Treatment with halofuginone results in marked growth inhibition of a von Hippel-Lindau pheochromocytoma in vivo.
Topics: Animals; Antineoplastic Agents; Cell Division; Collagen; Collagen Type I; Disease Progression; Electrophoresis, Polyacrylamide Gel; Humans; Immunohistochemistry; Magnetic Resonance Imaging; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Pheochromocytoma; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rats; Temperature; Time Factors; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Vascular Endothelial Growth Factor A; von Hippel-Lindau Disease; Von Hippel-Lindau Tumor Suppressor Protein | 2003 |
Inhibition of Wilms tumor xenograft progression by halofuginone is accompanied by activation of WT-1 gene expression.
Topics: Angiogenesis Inhibitors; Animals; Cell Line; Child, Preschool; Collagen; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization; Injections, Intraperitoneal; Kidney Neoplasms; Mice; Mice, Nude; Neovascularization, Pathologic; Piperidines; Proto-Oncogene Proteins c-met; Quinazolines; Quinazolinones; Receptor, ErbB-2; Transplantation, Heterologous; Wilms Tumor; WT1 Proteins | 2005 |
Gene expression during chemically induced liver fibrosis: effect of halofuginone on TGF-beta signaling.
Topics: Acid Phosphatase; Animals; Antineoplastic Agents; Cluster Analysis; Cytoglobin; Disease Progression; Fibrillin-1; Fibrillins; Gene Expression Profiling; Gene Expression Regulation; Globins; Hepatocytes; Humans; Isoenzymes; Liver Cirrhosis; Male; Microfilament Proteins; Nuclear Proteins; Osteopontin; Phosphorylation; Piperidines; Quinazolinones; Rats; Rats, Wistar; Signal Transduction; Smad2 Protein; Smad3 Protein; Substrate Specificity; Tartrate-Resistant Acid Phosphatase; Thioacetamide; Transforming Growth Factor beta | 2007 |
Growth inhibition of prostate cancer xenografts by halofuginone.
Topics: Adenocarcinoma; Administration, Oral; Androgens; Animals; Antineoplastic Agents; Apoptosis; Collagen Type I; Disease Progression; DNA, Neoplasm; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; In Situ Hybridization; Injections, Intraperitoneal; Male; Mice; Mice, SCID; Necrosis; Neovascularization, Pathologic; Phenotype; Piperidines; Prostatic Neoplasms; Quinazolines; Quinazolinones | 2002 |