Page last updated: 2024-08-23

halofantrine and Malaria

halofantrine has been researched along with Malaria in 81 studies

*Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia. [MeSH]

Research

Studies (81)

Timeframe	Studies, this research(%)	All Research%
pre-1990	18 (22.22)	18.7374
1990's	45 (55.56)	18.2507
2000's	14 (17.28)	29.6817
2010's	3 (3.70)	24.3611
2020's	1 (1.23)	2.80

Authors

Authors	Studies
Berrang, B; Carroll, FI; Linn, CP	1
Craig, PN; Fukunaga, JY; Hansch, C; Jow, PY; Kim, KH; Page, J; Steller, EE	1
Malik, H; Puri, SK; Singh, C	1
Bambal, RB; Bates, M; Berry, N; Biagini, GA; Bonar-Law, R; Bray, PG; Brigandi, RA; Davis, CB; Gargallo, DV; Gibbons, P; Gomez-delas-Heras, FM; Gresham, SL; Hart, TK; Hindley, S; Lawrence, RM; Maggs, JL; Mukhtar, A; O'Neill, PM; Park, BK; Roberts, P; Shone, AE; Stocks, PA; Ward, SA; Winstanley, PA	1
Caridha, D; Gerena, L; Korotchenko, V; Kreishman-Deitrick, M; Li, Q; Lin, AJ; Sathunuru, R; Smith, PL	1
Avery, VM; Buchholz, M; Delves, MJ; Duffy, S; Fischli, C; Held, J; Knaab, TC; Kuna, K; Kurz, T; Lehmann, U; Leven, M; Lungerich, B; Meister, S; Meitzner, D; Mordmüller, B; Stahlke, P; Winzeler, EA; Wittlin, S	1
Adnan, M; Ashraf, SA; Badraoui, R; Bhardwaj, J; Goyal, M; Hamadou, WS; Jahan, S; Jamal, A; Sachidanandan, M; Sharma, P; Siddiqui, AJ; Snoussi, M	1
Adewunmi, CO; Agbedahunsi, JM; Ijarotimi, SO; Onyeji, CO	1
Barratt, G; Bories, C; Legrand, P; Loiseau, P; Mosqueira, V	1
Hayton, K; Su, XZ	1
Barratt, G; Bories, C; Devissaguet, JP; Legrand, P; Loiseau, PM; Mosqueira, VC	1
Dumotier, B; Traebert, M	1
Barratt, G; Grabe-Guimarães, A; Guimarães, HN; Leite, EA; Machado-Coelho, GL; Mosqueira, VC	1
Falade, CO; Fehintola, FA; Sowunmi, A	1
Croft, AM	1
Black, J	1
Boudreau, EF; Pavanand, K; Thosingha, L; Webster, HK	1
Boudreau, EF; Canfield, CJ; Cosgriff, TM; Desjardins, RE; Doberstyn, EB; Pamplin, CL	1
Duong, TH; Igwangou, P; Kombila, M; Ngou-Milama, E; Ozouaki, P	1
Wadhwa, S	1
Ager, A; Andersen, SL; Berman, J; Ellis, W; Kuschner, R; McGreevy, P; Ohrt, C; Rossan, R; Schuster, BG; Wesche, D	1
Bagade, AC; Bilolikar, HG; Gambhir, PS; Phadke, MA	1
Edwards, G; Ward, SA; Winstanley, PA	1
Aubry, AF; Basco, LK; Bouchaud, O; Farinotti, R; Gillotin, C; Gimenez, F; Le Bras, J; Wainer, IW	1
Hatton, P	1
Bakker, RB; Lampe, AS; Smith, SJ	2
Bradley, DJ	1
Bhattacharyya, PC; Kakati, S; Saikia, PK; Sarma, PC	1
Kretschmer, H	1
Bock, HL; Braendli, B; Clemens, R; Fleischer, K; Kretschmer, H; Löscher, T; Markwalder, K; Nothdurft, HD; Schlunk, T; Weinke, T	1
Bock, HL; Clemens, R; Löscher, T; Nothdurft, HD	1
Horton, J	1
Touze, JE	1
Nicolas, F; Nicolas, X	1
Angel, G; Aulagnier, V; Diatta, B; Seck, M; Seignot, P	1
Fleck, SL; Peters, W; Robinson, BL	1
Boele van Hensbroek, M; Kager, PA; Wetsteyn, JC; Zijlmans, CW	1
Bangchang, KN; Farinotti, R; Gimenez, F; Gorichon, E; Karbwang, J; Martin, C; Thuillier, A	1
Backmund, M; Eichenlaub, D; Hartmann, WJ; Hesse, J; von Zielonka, M	1
Bourgeade, A; Delmont, J	1
Dumon, H; Garnier, JM; Lanza-Silhol, F; Minodier, P; Piarroux, R; Unal, D	1
Makonnen, E; Mengesha, T	1
Lagardère, B; Laurent, C; Thibault, H	1
Gendrel, D; Imbert, P; Lavallée, I; Marc, E; Moulin, F; Treluyer, JM	1
Adam, M; Bégué, P; Delée, S; Favier, R; Grimprel, E; Parez, N; Quinet, B	1
Kager, PA	1
Bock, HL; Clemens, R; Fleischer, K; Kohler, B; Kretschmer, H; Loscher, T; Pohle, HD; Schlunk, T; Weinke, T	1
Kidson, C	1
Trigg, PI	1
Abila, B; Ambakederemo, AW; Ezeamuzie, IC; Igbigbi, PS; Nwaejike, IN	1
Khan, MA; Qazi, SA; Rehman, GN	1
Edwards, G; Karbwang, J; Milton, KA; Na Bangchang, K; Ward, SA	1
Coulaud, JP; LeBras, J; Ringwald, P; Voyer, C	1
Baudon, D; Bernard, J; Lantrade, P; Martet, G; Moulia-Pelat, JP; Picq, JJ; Sarrouy, J; Spiegel, A; Touze, JE	1
Bustos, DG; Danis, M; Diquet, B; Gay, F; Gentilini, M; Litaudon, M; Pichet, C; Rojas Rivero, L	1
Bunnag, D; Edwards, G; Karbwang, J; Milton, KA; Na Bangchang, K; Ward, SA	1
Edstein, MD; Keeratithakul, D; Shanks, GD; Teja-Isavadharm, P; Webster, HK	1
Le Bras, M; Mazaudier, E; Raccurt, CP; Ripert, C; Schmitt, A	1
Becker, JM; Bernard, J; Dupasquier, I; Geffray, L; Gimenez, M; Jourdan, G; Lesbordes, JL; Molinas, JM; Sarrouy, J	1
Bokor, LC; Horton, RJ; Parr, SN	1
Jeandel, P; Touze, JE	1
Bustos, MD; Danis, M; Diquet, B; Félix, R; Gay, F; Gentilini, M; Lyogoubi, A	1
Kayembe, N; Kingway, MP; Mashako, MN	1
Bustos, D; Caumes, E; Danis, M; Datry, A; Diquet, B; Gay, F; Gentilini, M; Litaudon, M	1
Bouloumie, J; Lambert, MT; Macaigne, F; Raccurt, CP; Ribou, G; Ripert, C	1
Gilles, HM; Kariuki, D; Koech, DK; Lury, JD; Mjomba, M; Mosoba, M; Oloo, JA; Watkins, WM	1
Gilles, HM; Khoromana, C; Molyneux, ME; Wirima, J	1
Carles, G; John, M; Joly, F; Maisonneuve, H; Rossignol, JF	1
Boudreau, EF; Canfield, CJ; Dixon, KE; Pang, LW; Pavanand, K; Somutsakorn, P; Tosingha, L; Webster, HK	1
Ellis, DS; Peters, W; Robinson, BL	1
Coulaud, JP; Le Bras, J; Matheron, S; Moriniere, B; Rossignol, JF; Saimot, AG	2
Boudreau, EF; Pang, LW; Pavanand, K; Webster, HK; Yongvanitchit, K	1
Canfield, CJ; Cosgriff, TM; Pamplin, CL; Willet, GP	1
Coulanges, P; Deloron, P; Le Bras, J; Ramanamirija, JA	1
Biaud, JM; Coulanges, P; Deloron, P; Le Bras, J; Ramanamirija, JA	1
Boudreau, EF; Pavanand, K; Pinswasdi, C; Thaithong, S; Webster, HK; Yongvanitchit, K	1

Reviews

9 review(s) available for halofantrine and Malaria

Article	Year
Genetic and biochemical aspects of drug resistance in malaria parasites. Current drug targets. Infectious disorders, 2004, Volume: 4, Issue:1 Topics: Animals; Antimalarials; Chloroquine; Dihydropteroate Synthase; Drug Resistance; Drug Resistance, Multiple; Humans; Linkage Disequilibrium; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Mutation; Phenanthrenes; Plasmodium falciparum; Plasmodium vivax; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase	2004
Antimalarial drugs: QT prolongation and cardiac arrhythmias. Expert opinion on drug safety, 2005, Volume: 4, Issue:3 Topics: Amodiaquine; Drug Approval; Electrophysiology; Humans; Long QT Syndrome; Malaria; Phenanthrenes; Risk Assessment; Risk Factors; Torsades de Pointes	2005
A lesson learnt: the rise and fall of Lariam and Halfan. Journal of the Royal Society of Medicine, 2007, Volume: 100, Issue:4 Topics: Antimalarials; Drug Industry; Financing, Government; Forecasting; Humans; Interprofessional Relations; Malaria; Mefloquine; Mental Disorders; Military Personnel; Phenanthrenes; Technology, Pharmaceutical; United States; United States Food and Drug Administration	2007
Clinical pharmacokinetics in the treatment of tropical diseases. Some applications and limitations. Clinical pharmacokinetics, 1994, Volume: 27, Issue:2 Topics: Chloroquine; Diethylcarbamazine; Drug Resistance; Echinococcosis; Filariasis; Humans; Malaria; Mefloquine; Pharmacokinetics; Phenanthrenes; Pyrimethamine; Quinine; Sulfadoxine; Tropical Medicine	1994
Halofantrine: a new substance for treatment of multidrug-resistant malaria. The Clinical investigator, 1993, Volume: 71, Issue:1 Topics: Acute Disease; Adult; Animals; Antimalarials; Child, Preschool; Drug Evaluation; Humans; Incidence; Infant; Malaria; Malaria, Falciparum; Malaria, Vivax; Phenanthrenes; Plasmodium falciparum; Prospective Studies; Travel	1993
[Correct usage of amino alcohols]. Medecine tropicale : revue du Corps de sante colonial, 1995, Volume: 55, Issue:3 Suppl Topics: Antimalarials; Clinical Protocols; Drug Administration Schedule; Drug Resistance; Humans; Malaria; Mefloquine; Phenanthrenes; Quinine	1995
[The treatment of malaria]. Nederlands tijdschrift voor geneeskunde, 1997, Sep-13, Volume: 141, Issue:37 Topics: Adult; Antimalarials; Chloroquine; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Phenanthrenes; Pregnancy; Primaquine	1997
Comparative efficacy and safety of chloroquine and alternative antimalarial drugs: a meta-analysis from six African countries. East African medical journal, 1999, Volume: 76, Issue:6 Topics: Africa, Eastern; Africa, Western; Amodiaquine; Antimalarials; Chloroquine; Drug Combinations; Drug Costs; Humans; Malaria; Mefloquine; Patient Selection; Phenanthrenes; Pyrimethamine; Quinine; Safety; Sulfadoxine; Treatment Outcome	1999
Halofantrine in the treatment of malaria. Lancet (London, England), 1989, Sep-02, Volume: 2, Issue:8662 Topics: Administration, Oral; Animals; Antimalarials; Drug Administration Schedule; Drug Evaluation; Half-Life; Humans; Malaria; Phenanthrenes; Plasmodium falciparum	1989

Trials

10 trial(s) available for halofantrine and Malaria

Article	Year
Efficacy of halofantrine in malaria. Indian pediatrics, 1994, Volume: 31, Issue:5 Topics: Antimalarials; Child; Child, Preschool; Female; Humans; Infant; Malaria; Male; Phenanthrenes	1994
[Halofantrine in the treatment of imported malaria in nonimmune travelers]. Deutsche medizinische Wochenschrift (1946), 1993, Feb-26, Volume: 118, Issue:8 Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Drug Therapy, Combination; Drug Tolerance; Female; Germany; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Phenanthrenes; Plasmodium malariae; Primaquine; Prospective Studies; Recurrence; Switzerland; Time Factors; Travel	1993
Halofantrine: a new substance for treatment of multidrug-resistant malaria. The Clinical investigator, 1993, Volume: 71, Issue:1 Topics: Acute Disease; Adult; Animals; Antimalarials; Child, Preschool; Drug Evaluation; Humans; Incidence; Infant; Malaria; Malaria, Falciparum; Malaria, Vivax; Phenanthrenes; Plasmodium falciparum; Prospective Studies; Travel	1993
[Monitoring of long QT interval during treatment of malaria with halofantrine]. Medecine tropicale : revue du Corps de sante colonial, 1995, Volume: 55, Issue:4 Topics: Adolescent; Adult; Antimalarials; Drug Monitoring; Electrocardiography; Humans; Long QT Syndrome; Malaria; Male; Phenanthrenes; Prospective Studies	1995
[Halofantrine in pediatrics: survey in Ile-de-France]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2001, Volume: 8 Suppl 2 Topics: Antimalarials; Child; France; Humans; Malaria; Phenanthrenes	2001
The efficacy of halofantrine in the treatment of acute malaria in nonimmune travelers. The American journal of tropical medicine and hygiene, 1992, Volume: 47, Issue:1 Topics: Acute Disease; Adult; Antimalarials; Drug Resistance; Drug Tolerance; Female; Follow-Up Studies; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Phenanthrenes; Travel	1992
Halofantrine-induced pruritus amongst subjects who itch to chloroquine. The Journal of tropical medicine and hygiene, 1991, Volume: 94, Issue:3 Topics: Acute Disease; Adolescent; Adult; Antimalarials; Chloroquine; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Kinetics; Malaria; Male; Middle Aged; Pain Measurement; Phenanthrenes; Pruritus	1991
Efficacy of multiple-dose halofantrine in treatment of chloroquine-resistant falciparum malaria in children in Kenya. Lancet (London, England), 1988, Jul-30, Volume: 2, Issue:8605 Topics: Administration, Oral; Adolescent; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Drug Resistance; Female; Follow-Up Studies; Half-Life; Humans; Infant; Kenya; Malaria; Male; Phenanthrenes; Plasmodium falciparum; Time Factors	1988
Clinical trials with halofantrine hydrochloride in Malawi. Lancet (London, England), 1988, Jul-30, Volume: 2, Issue:8605 Topics: Administration, Oral; Adolescent; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Female; Follow-Up Studies; Humans; Infant; Malaria; Malawi; Male; Phenanthrenes; Plasmodium falciparum; Recurrence; Time Factors	1988
Malaria: treatment efficacy of halofantrine (WR 171,669) in initial field trials in Thailand. Bulletin of the World Health Organization, 1988, Volume: 66, Issue:2 Topics: Adult; Antimalarials; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Humans; Malaria; Male; Mefloquine; Middle Aged; Phenanthrenes; Quinolines; Random Allocation	1988

Other Studies

63 other study(ies) available for halofantrine and Malaria

Article	Year
Resolution of antimalarial agents via complex formation with alpha-(2,4,5,7-tetranitro-9-fluorenylideneaminooxy) propionic acid. Journal of medicinal chemistry, 1978, Volume: 21, Issue:4 Topics: Animals; Antimalarials; Fluorenes; Malaria; Methods; Mice; Optical Rotation; Plasmodium berghei; Propionates; Stereoisomerism	1978
Quantitative structure-activity relationships in 1-aryl-2-(alkylamino)ethanol antimalarials. Journal of medicinal chemistry, 1979, Volume: 22, Issue:4 Topics: Animals; Antimalarials; Ethanolamines; Malaria; Mice; Models, Biological; Phenanthrenes; Plasmodium berghei; Pyridines; Quinolines; Structure-Activity Relationship	1979
Orally active 1,2,4-trioxanes: synthesis and antimalarial assessment of a new series of 9-functionalized 3-(1-arylvinyl)-1,2,5-trioxaspiro[5.5]undecanes against multi-drug-resistant plasmodium yoelii nigeriensis in mice. Journal of medicinal chemistry, 2006, May-04, Volume: 49, Issue:9 Topics: Administration, Oral; Amination; Animals; Antimalarials; Artemisinins; Drug Resistance, Multiple; Heterocyclic Compounds; Malaria; Mice; Molecular Structure; Plasmodium yoelii; Structure-Activity Relationship; Survival Rate	2006
Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century. Journal of medicinal chemistry, 2009, Mar-12, Volume: 52, Issue:5 Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Benzylamines; Cytochrome P-450 Enzyme Inhibitors; Dogs; Drug Evaluation, Preclinical; Drug Resistance; Female; Haplorhini; Heme; Humans; Malaria; Mice; Models, Molecular; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Rats; Structure-Activity Relationship	2009
Antimalarial activity of 4-amidinoquinoline and 10-amidinobenzonaphthyridine derivatives. Journal of medicinal chemistry, 2015, Apr-23, Volume: 58, Issue:8 Topics: Animals; Antimalarials; Hep G2 Cells; Humans; Malaria; Malaria, Falciparum; Male; Mice; Naphthyridines; Plasmodium berghei; Plasmodium falciparum; Quinolines	2015
3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally. Journal of medicinal chemistry, 2017, 07-27, Volume: 60, Issue:14 Topics: Amides; Animals; Antimalarials; Hep G2 Cells; Humans; Hydrazones; Malaria; Mice; Phenanthrenes; Plasmodium berghei; Stereoisomerism; Structure-Activity Relationship	2017
Impact of chemoprophylaxis immunisation under halofantrine (CPS-HF) drug cover in Plasmodium yoelii Swiss mice malaria model. Folia parasitologica, 2022, Feb-03, Volume: 69 Topics: Animals; Chemoprevention; Immunization; Malaria; Mice; Mice, Inbred BALB C; Pharmaceutical Preparations; Phenanthrenes; Plasmodium yoelii	2022
Chemotherapeutic interaction between Khaya grandifoliola (WELW) CDC stem bark extract and two anti-malarial drugs in mice. African journal of traditional, complementary, and alternative medicines : AJTCAM, 2010, Volume: 7, Issue:4 Topics: Administration, Oral; Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Female; Malaria; Meliaceae; Mice; Nigeria; Phenanthrenes; Plant Bark; Plant Extracts; Plasmodium yoelii; Treatment Outcome	2010
[Long circulating nanocapsules: interest in the treatment of severe malaria with halofantrine]. Annales pharmaceutiques francaises, 2003, Volume: 61, Issue:3 Topics: Animals; Antimalarials; Capsules; Chemical Phenomena; Chemistry, Physical; Drug Delivery Systems; Malaria; Mice; Phenanthrenes; Plasmodium berghei; Solubility	2003
Efficacy and pharmacokinetics of intravenous nanocapsule formulations of halofantrine in Plasmodium berghei-infected mice. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:4 Topics: Animals; Antimalarials; Area Under Curve; Biotransformation; Capsules; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Injections, Intravenous; Malaria; Mice; Phenanthrenes; Plasmodium berghei	2004
Cardiotoxicity reduction induced by halofantrine entrapped in nanocapsule devices. Life sciences, 2007, Mar-13, Volume: 80, Issue:14 Topics: Animals; Antimalarials; Bradycardia; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Heart; Hypotension; Lethal Dose 50; Long QT Syndrome; Malaria; Male; Mice; Nanocapsules; Phenanthrenes; Plasmodium berghei; Rats; Rats, Wistar	2007
Intravascular haemolysis following treatment of malaria with halofantrine: case report. Nigerian journal of clinical practice, 2006, Volume: 9, Issue:2 Topics: Antimalarials; Child; Child, Preschool; Hemolysis; Humans; Malaria; Male; Nigeria; Phenanthrenes; Risk Factors	2006
Lariam and Halfan. Journal of the Royal Society of Medicine, 2007, Volume: 100, Issue:8 Topics: Antimalarials; Humans; Malaria; Mefloquine; Mental Disorders; Phenanthrenes; Randomized Controlled Trials as Topic; Time Factors	2007
Type II mefloquine resistance in Thailand. Lancet (London, England), 1982, Dec-11, Volume: 2, Issue:8311 Topics: Adult; Antimalarials; Drug Resistance, Microbial; Humans; Malaria; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinolines; Thailand	1982
Evaluation of the antimalarial activity of the phenanthrenemethanol halofantrine (WR 171,669). The American journal of tropical medicine and hygiene, 1982, Volume: 31, Issue:6 Topics: Animals; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Humans; Malaria; Phenanthrenes; Plasmodium falciparum; Recurrence	1982
Use of halofantrine as standby treatment for malaria. Communicable disease report. CDR weekly, 1993, Dec-17, Volume: 3, Issue:51 Topics: Antimalarials; Contraindications; Humans; Malaria; Phenanthrenes	1993
[Variation of cholostase enzymes (5'-nucleotidase and alkaline phosphatase) during a specific treatment for malaria in the Gabonese child]. Bulletin de la Societe de pathologie exotique (1990), 1995, Volume: 88, Issue:1 Topics: 5'-Nucleotidase; Alkaline Phosphatase; Antimalarials; Child; Child, Preschool; Drug Combinations; Gabon; Humans; Infant; Malaria; Mefloquine; Phenanthrenes; Pyrimethamine; Reference Values; Sulfadoxine	1995
Halofantrine in acute malaria. The Journal of the Association of Physicians of India, 1994, Volume: 42, Issue:5 Topics: Antimalarials; Blood Coagulation Disorders; Humans; Liver Diseases; Malaria; Phenanthrenes; Serum Albumin	1994
Activity of azithromycin as a blood schizonticide against rodent and human plasmodia in vivo. The American journal of tropical medicine and hygiene, 1995, Volume: 52, Issue:2 Topics: Administration, Oral; Animals; Antimalarials; Aotus trivirgatus; Artemisinins; Azithromycin; Disease Models, Animal; Doxycycline; Drug Therapy, Combination; Humans; Injections, Subcutaneous; Malaria; Malaria, Falciparum; Mice; Parasitemia; Phenanthrenes; Plasmodium berghei; Quinine; Sesquiterpenes	1995
Plasma concentrations of the enantiomers of halofantrine and its main metabolite in malaria patients. European journal of clinical pharmacology, 1994, Volume: 46, Issue:6 Topics: Adult; Antimalarials; Humans; Malaria; Middle Aged; Phenanthrenes; Stereoisomerism	1994
Antimalarial prophylaxis. Journal of public health medicine, 1994, Volume: 16, Issue:3 Topics: Antimalarials; Arrhythmias, Cardiac; Humans; Malaria; Phenanthrenes; Self Medication	1994
Dangers of antimalarial standby treatment. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1994, Volume: 13, Issue:4 Topics: Antimalarials; Appendicitis; Diagnostic Errors; Humans; Malaria; Male; Netherlands; Papua New Guinea; Phenanthrenes; Self Administration; Travel	1994
Antimalarial prophylaxis. Manufacturers recommend more stringent guidelines for halofantrine. BMJ (Clinical research ed.), 1994, Mar-12, Volume: 308, Issue:6930 Topics: Antimalarials; Humans; Malaria; Phenanthrenes	1994
Clinical evaluation of halofantrine in acute malaria. The Journal of the Association of Physicians of India, 1993, Volume: 41, Issue:8 Topics: Acute Disease; Adolescent; Adult; Antimalarials; Child; Female; Humans; Malaria; Male; Middle Aged; Phenanthrenes	1993
[Halofantrine in the treatment of imported malaria in non-immune travelers]. Deutsche medizinische Wochenschrift (1946), 1993, Aug-06, Volume: 118, Issue:31 Topics: Antimalarials; Female; Humans; Malaria; Male; Middle Aged; Phenanthrenes; Travel	1993
[Mislead by 'malaria medication in one's pocket']. Nederlands tijdschrift voor geneeskunde, 1993, Aug-14, Volume: 137, Issue:33 Topics: Antimalarials; Appendicitis; Diagnosis, Differential; Fever; Humans; Malaria; Male; Middle Aged; Phenanthrenes	1993
Halofantrine in the treatment of malaria. Drug safety, 1995, Volume: 13, Issue:4 Topics: Administration, Oral; Antimalarials; Humans; Malaria; Phenanthrenes	1995
[2 cases of malarial flare-up with fatal outcome inspite of treatment with halofantrine]. Presse medicale (Paris, France : 1983), 1996, Nov-02, Volume: 25, Issue:33 Topics: Adult; Antimalarials; Fatal Outcome; Humans; Malaria; Male; Middle Aged; Phenanthrenes	1996
The chemotherapy of rodent malaria. LIV. Combinations of 'Fenozan B07' (Fenozan-50F), a difluorinated 3,3'-spirocyclopentane 1,2,4-trioxane, with other drugs against drug-sensitive and drug-resistant parasites. Annals of tropical medicine and parasitology, 1997, Volume: 91, Issue:1 Topics: Aminoquinolines; Animals; Antimalarials; Chloroquine; Drug Antagonism; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Malaria; Mefloquine; Mice; Naphthyridines; Parasitemia; Phenanthrenes; Phenylpropionates; Plasmodium berghei; Plasmodium yoelii	1997
Chiral chromatographic method to determine the enantiomers of halofantrine and its main chiral desbutyl metabolite in erythrocytes. Journal of chromatography. B, Biomedical sciences and applications, 1998, Aug-07, Volume: 712, Issue:1-2 Topics: Administration, Oral; Antimalarials; Chromatography, Liquid; Erythrocytes; Humans; Malaria; Phenanthrenes; Reproducibility of Results; Stereoisomerism	1998
[Malaria--state of the art. 2: Therapy and prevention of malaria]. Fortschritte der Medizin, 1999, Jan-20, Volume: 117, Issue:1-2 Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Emergencies; Humans; Infant; Malaria; Phenanthrenes; Plasmodium falciparum; Quinine; Travel; Tropical Climate	1999
[The proper use of antimalarial drugs currently available]. Bulletin de la Societe de pathologie exotique (1990), 1998, Volume: 91, Issue:5 Pt 1-2 Topics: Animals; Antimalarials; Chemoprevention; Chloroquine; Contraindications; Drug Combinations; Drug Resistance; Endemic Diseases; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Phenanthrenes; Plasmodium; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Proguanil; Pyrimethamine; Quinine; Sulfadoxine; Travel	1998
[Imported pediatric malaria in Marseille]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1999, Volume: 6, Issue:9 Topics: Adolescent; Antimalarials; Child; Child, Preschool; Comorbidity; Emigration and Immigration; Female; France; Humans; Infant; Malaria; Malaria, Falciparum; Male; Phenanthrenes; Recurrence; Travel	1999
Sudden death in a traveller following halofantrine administration--Togo, 2000. Canada communicable disease report = Releve des maladies transmissibles au Canada, 2001, Jul-15, Volume: 27, Issue:14 Topics: Adult; Antimalarials; Cardiomyopathy, Hypertrophic; Contraindications; Death, Sudden, Cardiac; Humans; Long QT Syndrome; Malaria; Male; Mefloquine; Phenanthrenes; Togo; Travel	2001
[Cardiac rhythm disturbances and prolonged QT interval with halofantrine]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2001, Volume: 8, Issue:8 Topics: Adolescent; Antimalarials; Bradycardia; Child; Child, Preschool; Electrocardiography; Female; Humans; Infant; Long QT Syndrome; Malaria; Male; Phenanthrenes	2001
[Imported malaria in children in 1999. Study of the Armand-Trousseau Hospital in Paris]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2002, Volume: 9, Issue:4 Topics: Adolescent; Antimalarials; Child; Child, Preschool; Emigration and Immigration; Female; Hospitalization; Humans; Incidence; Infant; Malaria; Male; Paris; Phenanthrenes; Recurrence; Retrospective Studies; Travel	2002
[Malaria prophylaxis]. Nederlands tijdschrift voor geneeskunde, 1992, Dec-26, Volume: 136, Issue:52 Topics: Animals; Antimalarials; Culicidae; Humans; Insect Bites and Stings; Malaria; Phenanthrenes	1992
Malaria vaccines in the future--what strategies now? The Southeast Asian journal of tropical medicine and public health, 1991, Volume: 22, Issue:2 Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Forecasting; Humans; Malaria; Mosquito Control; Phenanthrenes; Plasmodium; Protozoan Vaccines	1991
Drug use and design in the nineties. Acta Leidensia, 1991, Volume: 60, Issue:1 Topics: Aminoquinolines; Amodiaquine; Antimalarials; Artemisinins; Calcium Channel Blockers; Chloroquine; Humans; Malaria; Mefloquine; Naphthoquinones; Phenanthrenes; Primaquine; Quinine; Sesquiterpenes; Sulfadoxine	1991
Halofantrine hydrochloride--efficacy and safety in children with acute malaria. JPMA. The Journal of the Pakistan Medical Association, 1991, Volume: 41, Issue:1 Topics: Acute Disease; Animals; Antimalarials; Child; Child, Preschool; Female; Humans; Infant; Malaria; Male; Phenanthrenes; Plasmodium falciparum; Plasmodium vivax; Safety	1991
Pharmacokinetics of halofantrine in healthy Thai volunteers. British journal of clinical pharmacology, 1991, Volume: 32, Issue:5 Topics: Adolescent; Adult; Antimalarials; Humans; Malaria; Male; Middle Aged; Phenanthrenes; Thailand	1991
Reduced in vitro susceptibility to halofantrine of Plasmodium falciparum in West Africa. Lancet (London, England), 1990, Feb-17, Volume: 335, Issue:8686 Topics: Adult; Africa, Western; Animals; Antimalarials; Drug Resistance; Humans; In Vitro Techniques; Malaria; Male; Phenanthrenes; Plasmodium falciparum; Recurrence; Travel	1990
Halofantrine to prevent falciparum malaria on return from malarious areas. Lancet (London, England), 1990, Aug-11, Volume: 336, Issue:8711 Topics: Africa, Central; Animals; Antimalarials; Humans; Malaria; Male; Phenanthrenes; Plasmodium falciparum; Travel	1990
Cross-resistance between mefloquine and halofantrine. Lancet (London, England), 1990, Nov-17, Volume: 336, Issue:8725 Topics: Adult; Animals; Antimalarials; Drug Resistance; Humans; Malaria; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum	1990
Pharmacokinetics of halofantrine in Thai patients with acute uncomplicated falciparum malaria. British journal of clinical pharmacology, 1991, Volume: 31, Issue:4 Topics: Acute Disease; Adolescent; Adult; Animals; Antimalarials; Humans; Malaria; Middle Aged; Phenanthrenes; Plasmodium falciparum	1991
An improved high-performance liquid chromatographic method for the simultaneous measurement of halofantrine and desbutylhalofantrine in human serum. Therapeutic drug monitoring, 1991, Volume: 13, Issue:1 Topics: Antimalarials; Chromatography, High Pressure Liquid; Humans; Malaria; Phenanthrenes; Ultraviolet Rays	1991
[Imported malaria in Bordeaux in 1989. Epidemiologic, clinical and therapeutic study of 71 cases]. Bulletin de la Societe de pathologie exotique (1990), 1990, Volume: 83, Issue:5 Topics: Animals; Antimalarials; Chloroquine; Female; France; Humans; Malaria; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Travel	1990
[The treatment of imported Plasmodium falciparum malaria with halofantrine. Apropos of 59 case reports (corrected and republished article orginally printed in Med Trop (Mars) 1990 Jan-Mar;50(1):113-7)]. Medecine tropicale : revue du Corps de sante colonial, 1990, Volume: 50, Issue:2 Topics: Adolescent; Adult; Animals; Antimalarials; Chloroquine; Drug Resistance; Female; Humans; Malaria; Male; Phenanthrenes; Plasmodium falciparum; Travel	1990
Clinical experience with halofantrine in the treatment of malaria. Drugs under experimental and clinical research, 1990, Volume: 16, Issue:10 Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Child; Child, Preschool; Evaluation Studies as Topic; Follow-Up Studies; Hematologic Tests; Humans; Infant; Liver Function Tests; Malaria; Male; Middle Aged; Phenanthrenes; Plasmodium falciparum; Plasmodium vivax	1990
[Clinical and therapeutic approach in Plasmodium falciparum malaria in non-immune patients]. Presse medicale (Paris, France : 1983), 1990, Apr-14, Volume: 19, Issue:15 Topics: Animals; Drug Resistance, Microbial; Humans; Malaria; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine	1990
[Cross resistance to mefloquine and halofantrine in a case of P. falciparum malaria contracted in Sierra Leone]. Bulletin de la Societe de pathologie exotique (1990), 1990, Volume: 83, Issue:1 Topics: Adult; Animals; Antimalarials; Chloroquine; Cross Reactions; Drug Resistance; Humans; Malaria; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum	1990
[Halofantrine hydrochloride in the treatment of Plasmodium falciparum malaria in a region of resistance. Analysis of 54 pediatric cases]. Annales de la Societe belge de medecine tropicale, 1990, Volume: 70, Issue:1 Topics: Animals; Antimalarials; Child; Child, Preschool; Democratic Republic of the Congo; Drug Resistance; Female; Humans; Infant; Malaria; Male; Phenanthrenes; Plasmodium falciparum	1990
[Insufficiency of treatment with halofantrine in chloroquinoresistant Plasmodium falciparum malaria in Sierra Leone]. Annales de medecine interne, 1990, Volume: 141, Issue:5 Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Resistance; Female; Humans; Malaria; Phenanthrenes; Plasmodium falciparum; Sierra Leone	1990
[Halofantrine in the treatment of malaria. Clinical trial in a semi-rural zone of Cameroon]. Bulletin de la Societe de pathologie exotique et de ses filiales, 1989, Volume: 82, Issue:3 Topics: Adolescent; Animals; Antimalarials; Cameroon; Child; Child, Preschool; Female; Humans; Malaria; Male; Phenanthrenes; Plasmodium falciparum; Rural Population	1989
[Efficacy of halofantrine in Plasmodium falciparum or Plasmodium vivax malaria in a resistance area (French Guiana)]. Presse medicale (Paris, France : 1983), 1988, Jan-30, Volume: 17, Issue:3 Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Drug Resistance; Drug Tolerance; Female; French Guiana; Humans; Infant; Malaria; Male; Middle Aged; Phenanthrenes; Plasmodium falciparum; Plasmodium vivax	1988
The chemotherapy of rodent malaria. XLII. Halofantrine and halofantrine resistance. Annals of tropical medicine and parasitology, 1987, Volume: 81, Issue:5 Topics: Animals; Antimalarials; Drug Resistance; Malaria; Male; Mice; Phenanthrenes; Plasmodium berghei	1987
Treatment of imported cases of falciparum malaria in France with halofantrine. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1986, Volume: 80, Issue:4 Topics: Adult; Antimalarials; Female; France; Humans; Malaria; Male; Middle Aged; Phenanthrenes; Plasmodium falciparum	1986
Antimalarial drug susceptibility testing of Plasmodium falciparum in Thailand using a microdilution radioisotope method. The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:2 Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Lethal Dose 50; Malaria; Male; Mefloquine; Microbial Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine; Quinolines; Thailand	1985
Mefloquine failure in a case of falciparum malaria induced with a multidrug-resistant isolate in a non-immune subject. The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:4 Topics: Adult; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Pyridines; Quinine; Quinolines	1985
Plasmodium falciparum in Madagascar: in vivo and in vitro sensitivity to seven drugs. Annals of tropical medicine and parasitology, 1985, Volume: 79, Issue:4 Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Humans; Infant; Madagascar; Malaria; Mefloquine; Microbial Sensitivity Tests; Middle Aged; Phenanthrenes; Piperazines; Plasmodium falciparum; Quinine; Quinolines	1985
[In vivo and in vitro sensitivity to 4-aminoquinolines of Plasmodium falciparum in Madagascar: results of 2 years' study]. Bulletin de la Societe de pathologie exotique et de ses filiales, 1985, Volume: 78, Issue:5 Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; In Vitro Techniques; Madagascar; Malaria; Phenanthrenes; Piperazines; Plasmodium falciparum; Quinine; Quinolines	1985
Cloning and characterization of mefloquine-resistant Plasmodium falciparum from Thailand. The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:6 Topics: Adult; Animals; Antimalarials; Clone Cells; Drug Resistance; Glucose-6-Phosphate Isomerase; Humans; Isoenzymes; Malaria; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinolines; Thailand	1985
[Treatment with halofantrine of Plasmodium falciparum malaria imported into France]. Bulletin de la Societe de pathologie exotique et de ses filiales, 1985, Volume: 78, Issue:5 Pt 2 Topics: Adult; Africa, Western; Antimalarials; Female; France; Humans; Malaria; Male; Middle Aged; Phenanthrenes; Plasmodium falciparum; Travel	1985