ha14-1 and Lymphoma, Follicular
ha14-1 has been researched along with Lymphoma, Follicular in 3 studies
ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate: a BH3 mimetic; synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia
Lymphoma, Follicular: Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the LYMPH NODES. The nodules resemble to some extent the GERMINAL CENTER of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular center B-LYMPHOCYTES.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Herein, we analyze for the first time the effects of a B-cell lymphoma 2 (Bcl-2) antagonist, HA14-1, alone and in combination with antineoplastic agents commonly used against follicular lymphoma, in human FL cell lines with t(14;18)." | 3.73 | HA14-1, a small molecule Bcl-2 antagonist, induces apoptosis and modulates action of selected anticancer drugs in follicular lymphoma B cells. ( Eray, M; Mättö, M; Pelkonen, J; Skommer, J; Wlodkowic, D, 2006) |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Skommer, J | 3 |
| Wlodkowic, D | 3 |
| Mättö, M | 1 |
| Eray, M | 1 |
| Pelkonen, J | 3 |
Other Studies
3 other studies available for ha14-1 and Lymphoma, Follicular
| Article | Year |
|---|---|
HA14-1, a small molecule Bcl-2 antagonist, induces apoptosis and modulates action of selected anticancer drugs in follicular lymphoma B cells.
Topics: Antineoplastic Agents; Benzopyrans; Cell Line, Tumor; Dexamethasone; DNA Fragmentation; Dose-Respons | 2006 |
Multiparametric analysis of HA14-1-induced apoptosis in follicular lymphoma cells.
Topics: Apoptosis; Benzopyrans; Caspase Inhibitors; Caspases; Cell Line, Tumor; Drug Screening Assays, Antit | 2006 |
Brefeldin A triggers apoptosis associated with mitochondrial breach and enhances HA14-1- and anti-Fas-mediated cell killing in follicular lymphoma cells.
Topics: Antibodies, Monoclonal; Apoptosis; Benzopyrans; Brefeldin A; Caspases; Cell Line, Tumor; Endoplasmic | 2007 |