ha14-1 has been researched along with Brill-Symmers Disease in 3 studies
ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate: a BH3 mimetic; synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia
| Excerpt | Relevance | Reference |
|---|---|---|
| " Herein, we analyze for the first time the effects of a B-cell lymphoma 2 (Bcl-2) antagonist, HA14-1, alone and in combination with antineoplastic agents commonly used against follicular lymphoma, in human FL cell lines with t(14;18)." | 3.73 | HA14-1, a small molecule Bcl-2 antagonist, induces apoptosis and modulates action of selected anticancer drugs in follicular lymphoma B cells. ( Eray, M; Mättö, M; Pelkonen, J; Skommer, J; Wlodkowic, D, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Skommer, J | 3 |
| Wlodkowic, D | 3 |
| Mättö, M | 1 |
| Eray, M | 1 |
| Pelkonen, J | 3 |
3 other studies available for ha14-1 and Brill-Symmers Disease
| Article | Year |
|---|---|
HA14-1, a small molecule Bcl-2 antagonist, induces apoptosis and modulates action of selected anticancer drugs in follicular lymphoma B cells.
Topics: Antineoplastic Agents; Benzopyrans; Cell Line, Tumor; Dexamethasone; DNA Fragmentation; Dose-Respons | 2006 |
Multiparametric analysis of HA14-1-induced apoptosis in follicular lymphoma cells.
Topics: Apoptosis; Benzopyrans; Caspase Inhibitors; Caspases; Cell Line, Tumor; Drug Screening Assays, Antit | 2006 |
Brefeldin A triggers apoptosis associated with mitochondrial breach and enhances HA14-1- and anti-Fas-mediated cell killing in follicular lymphoma cells.
Topics: Antibodies, Monoclonal; Apoptosis; Benzopyrans; Brefeldin A; Caspases; Cell Line, Tumor; Endoplasmic | 2007 |