gyy-4137 has been researched along with Stroke* in 1 studies
1 other study(ies) available for gyy-4137 and Stroke
| Article | Year |
|---|---|
Reduced Production of Hydrogen Sulfide and Sulfane Sulfur Due to Low Cystathionine β-Synthase Levels in Brain Astrocytes of Stroke-Prone Spontaneously Hypertensive Rats.
Stroke-prone spontaneously hypertensive rats (SHRSP/Izm; SHRSP) develop severe hypertension and die of cerebral stroke. However, the genetic mechanisms underlying their stroke susceptibility have not been clarified yet. In this study, we used astrocytes from the newborn brain cortex of spontaneously hypertensive rats (SHR/Izm; SHR) and SHRSP to find the difference of genetic characteristics. Astrocytes are known to have functions of vasodilation and nutrient uptake for neurons in the brain. The continuous generation of hydrogen peroxide (H Topics: Animals; Astrocytes; Brain; Cell Survival; Cells, Cultured; Cystathionine beta-Synthase; Glucose Oxidase; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Hydrogen Sulfide; Hypertension; Morpholines; Organothiophosphorus Compounds; Oxidative Stress; Rats, Inbred SHR; Stroke; Sulfur | 2016 |