gyy-4137 has been researched along with Pneumonia* in 1 studies
1 other study(ies) available for gyy-4137 and Pneumonia
| Article | Year |
|---|---|
Hydrogen sulfide ameliorates acute lung injury induced by infrarenal aortic cross-clamping by inhibiting inflammation and angiopoietin 2 release.
Infrarenal aortic cross-clamping (IAC) is a common procedure during infrarenal vascular operations. It often causes ischemia-reperfusion injury to lower limbs, resulting in systemic inflammation response and damage to remote organs (particularly lungs). Hydrogen sulfide (H. Wistar rats underwent IAC for 2 hours, followed by 4 hours of reperfusion. GYY4137 (a slow-releasing H. IAC induced a significant increase in plasma levels of H. The study indicates that H Topics: Acute Lung Injury; Alkynes; Angiopoietin-2; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Constriction; Cystathionine gamma-Lyase; Cytoprotection; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Glycine; Hydrogen Sulfide; Lung; Lyases; Male; Morpholines; Organothiophosphorus Compounds; Pneumonia; Proto-Oncogene Proteins c-akt; Rats, Wistar | 2017 |