gypsogenin has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 2 studies
*Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aksel, M; Alankuş, Ö; Bölükbaşı, SŞ; Çiftçi, H; Emirdağ, S; Fujita, M; Karayıldırım, T; Otsuka, M; Özmen, A; Radwan, MO; Sever, B; Sözer, E; Tateishi, H; Ulusoy, NG; Yaylı, N | 1 |
| Ali, TFS; Can, M; Ciftci, HI; Fujita, M; Koga, R; Ocak, Z; Otsuka, M; Ozturk, SE; Radwan, MO; Tateishi, H | 1 |
2 other study(ies) available for gypsogenin and Leukemia, Myelogenous, Chronic, BCR-ABL Positive
| Article | Year |
|---|---|
Design, semi-synthesis and examination of new gypsogenin derivatives against leukemia via Abl tyrosine kinase inhibition and apoptosis induction.
Topics: Apoptosis; Benzamides; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Docking Simulation; Piperazines; Protein Kinase Inhibitors; Pyrimidines | 2022 |
The First Pentacyclic Triterpenoid Gypsogenin Derivative Exhibiting Anti-ABL1 Kinase and Anti-chronic Myelogenous Leukemia Activities.
Topics: Antineoplastic Agents, Phytogenic; Binding Sites; Caryophyllaceae; Cell Survival; Cells, Cultured; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; K562 Cells; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocytes, Mononuclear; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Saponins; Signal Transduction; Triterpenes | 2018 |