gyki 52466 has been researched along with Epilepsy, Tonic-Clonic in 2 studies
GYKI 52466: an AMPA (non-NMDA) receptor antagonist; structure given in first source
Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kubová, H | 1 |
| Világi, I | 1 |
| Mikulecká, A | 1 |
| Mares, P | 1 |
| Smith, SE | 1 |
| Dürmüller, N | 1 |
| Meldrum, BS | 1 |
2 other studies available for gyki 52466 and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
Non-NMDA receptor antagonist GYKI 52466 suppresses cortical afterdischarges in immature rats.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Electric Stimulation; Electrodes, Im | 1997 |
The non-N-methyl-D-aspartate receptor antagonists, GYKI 52466 and NBQX are anticonvulsant in two animal models of reflex epilepsy.
Topics: Acoustic Stimulation; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepin | 1991 |