gyki 52466 has been researched along with Epilepsies, Myoclonic in 2 studies
GYKI 52466: an AMPA (non-NMDA) receptor antagonist; structure given in first source
Epilepsies, Myoclonic: A clinically diverse group of epilepsy syndromes characterized either by myoclonic seizures or by myoclonus in association with other seizure types. Myoclonic epilepsy syndromes are divided into three subtypes based on etiology: familial, cryptogenic, and symptomatic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two potent glutamate antagonists, NBQX and GYKI 52466, that act selectively on non-NMDA receptors, have been tested for anticonvulsant activity in 3 models of reflex epilepsy (sound-induced seizures in DBA/2 mice and in genetically epilepsy-prone rats and photically-induced myoclonus in Papio papio) and in amygdala kindled rats." | 3.68 | The effects of AMPA receptor antagonists on kindled seizures and on reflex epilepsy in rodents and primates. ( Chapman, AG; Craggs, MD; Dürmüller, N; Meldrum, BS; Smith, SE, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meldrum, BS | 2 |
| Craggs, MD | 1 |
| Dürmüller, N | 2 |
| Smith, SE | 2 |
| Chapman, AG | 1 |
2 other studies available for gyki 52466 and Epilepsies, Myoclonic
| Article | Year |
|---|---|
The effects of AMPA receptor antagonists on kindled seizures and on reflex epilepsy in rodents and primates.
Topics: Acoustic Stimulation; Amygdala; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cere | 1992 |
The non-N-methyl-D-aspartate receptor antagonists, GYKI 52466 and NBQX are anticonvulsant in two animal models of reflex epilepsy.
Topics: Acoustic Stimulation; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepin | 1991 |