gyki 52466 has been researched along with Bipolar Disorder in 1 studies
GYKI 52466: an AMPA (non-NMDA) receptor antagonist; structure given in first source
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We found that chronic administration of the antimanic agents lithium and valproate (VPA) reduced synaptic AMPA receptor GluR1/2 in hippocampal neurons in vitro and in vivo." | 1.35 | The role of hippocampal GluR1 and GluR2 receptors in manic-like behavior. ( Blumenthal, R; Chen, G; Creson, TK; Du, J; Falke, C; Gray, NA; Machado-Vieira, R; Manji, HK; Ren, M; Wang, Y; Wei, Y; Wu, LJ; Yuan, P; Zhuo, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Du, J | 1 |
| Creson, TK | 1 |
| Wu, LJ | 1 |
| Ren, M | 1 |
| Gray, NA | 1 |
| Falke, C | 1 |
| Wei, Y | 1 |
| Wang, Y | 1 |
| Blumenthal, R | 1 |
| Machado-Vieira, R | 1 |
| Yuan, P | 1 |
| Chen, G | 1 |
| Zhuo, M | 1 |
| Manji, HK | 1 |
1 other study available for gyki 52466 and Bipolar Disorder
| Article | Year |
|---|---|
The role of hippocampal GluR1 and GluR2 receptors in manic-like behavior.
Topics: Animals; Antimanic Agents; Behavior, Animal; Benzodiazepines; Bipolar Disorder; Cells, Cultured; Dis | 2008 |