gyki 52466 has been researched along with Benign Infantile Myoclonic Epilepsy in 2 studies
GYKI 52466: an AMPA (non-NMDA) receptor antagonist; structure given in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two potent glutamate antagonists, NBQX and GYKI 52466, that act selectively on non-NMDA receptors, have been tested for anticonvulsant activity in 3 models of reflex epilepsy (sound-induced seizures in DBA/2 mice and in genetically epilepsy-prone rats and photically-induced myoclonus in Papio papio) and in amygdala kindled rats." | 3.68 | The effects of AMPA receptor antagonists on kindled seizures and on reflex epilepsy in rodents and primates. ( Chapman, AG; Craggs, MD; Dürmüller, N; Meldrum, BS; Smith, SE, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meldrum, BS | 2 |
| Craggs, MD | 1 |
| Dürmüller, N | 2 |
| Smith, SE | 2 |
| Chapman, AG | 1 |
2 other studies available for gyki 52466 and Benign Infantile Myoclonic Epilepsy
| Article | Year |
|---|---|
The effects of AMPA receptor antagonists on kindled seizures and on reflex epilepsy in rodents and primates.
Topics: Acoustic Stimulation; Amygdala; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cere | 1992 |
The non-N-methyl-D-aspartate receptor antagonists, GYKI 52466 and NBQX are anticonvulsant in two animal models of reflex epilepsy.
Topics: Acoustic Stimulation; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepin | 1991 |