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gyki 52466 and Anxiety

gyki 52466 has been researched along with Anxiety in 4 studies

GYKI 52466: an AMPA (non-NMDA) receptor antagonist; structure given in first source

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Blockade of gamma-aminobutyric acid (GABAA) receptors in the anterior basolateral amygdala (BLA) with bicuculline methiodide results in an increase in heart rate, blood pressure and "anxiety" in rats."3.69Excitatory amino acid receptor antagonists block the cardiovascular and anxiety responses elicited by gamma-aminobutyric acidA receptor blockade in the basolateral amygdala of rats. ( Sajdyk, TJ; Shekhar, A, 1997)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jain, SK1
Zelena, D1
Xiang, K1
Tietz, EI1
Członkowska, A1
Siemiatkowski, M1
Płaźnik, A1
Sajdyk, TJ1
Shekhar, A1

Other Studies

4 other studies available for gyki 52466 and Anxiety

ArticleYear
Gender specific influence of endogenous glutamate release on stress-induced fear in rats.
    Endocrine regulations, 2011, Volume: 45, Issue:1

    Topics: Animals; Anxiety; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrosho

2011
Benzodiazepine-induced hippocampal CA1 neuron alpha-amino-3-hydroxy-5-methylisoxasole-4-propionic acid (AMPA) receptor plasticity linked to severity of withdrawal anxiety: differential role of voltage-gated calcium channels and N-methyl-D-aspartic acid re
    Behavioural pharmacology, 2007, Volume: 18, Issue:5-6

    Topics: Animals; Anxiety; Benzodiazepines; Calcium Channels, L-Type; Disease Models, Animal; Dizocilpine Mal

2007
Some behavioral effects of AMPA/kainate receptor agonist and antagonists.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1997, Volume: 48, Issue:3

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anim

1997
Excitatory amino acid receptor antagonists block the cardiovascular and anxiety responses elicited by gamma-aminobutyric acidA receptor blockade in the basolateral amygdala of rats.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepin

1997