gyki 52466 has been researched along with Absence Status in 2 studies
GYKI 52466: an AMPA (non-NMDA) receptor antagonist; structure given in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benzodiazepines such as diazepam may fail to effectively treat status epilepticus because benzodiazepine-sensitive GABA(A) receptors are progressively internalized with continued seizure activity." | 7.76 | Treatment of early and late kainic acid-induced status epilepticus with the noncompetitive AMPA receptor antagonist GYKI 52466. ( Fritsch, B; Joelle Donofrio, J; Rogawski, MA; Stott, JJ, 2010) |
| "Benzodiazepines such as diazepam may fail to effectively treat status epilepticus because benzodiazepine-sensitive GABA(A) receptors are progressively internalized with continued seizure activity." | 3.76 | Treatment of early and late kainic acid-induced status epilepticus with the noncompetitive AMPA receptor antagonist GYKI 52466. ( Fritsch, B; Joelle Donofrio, J; Rogawski, MA; Stott, JJ, 2010) |
| "Kainic acid (KA) has long been used in experimental animals to induce status epilepticus (SE)." | 3.70 | [31P]/[1H] nuclear magnetic resonance study of mitigating effects of GYKI 52466 on kainate-induced metabolic impairment in perfused rat cerebrocortical slices. ( Liachenko, S; Melick, JA; Tang, P; Xu, Y, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fritsch, B | 1 |
| Stott, JJ | 1 |
| Joelle Donofrio, J | 1 |
| Rogawski, MA | 1 |
| Tang, P | 1 |
| Liachenko, S | 1 |
| Melick, JA | 1 |
| Xu, Y | 1 |
2 other studies available for gyki 52466 and Absence Status
| Article | Year |
|---|---|
Treatment of early and late kainic acid-induced status epilepticus with the noncompetitive AMPA receptor antagonist GYKI 52466.
Topics: Animals; Anticonvulsants; Behavior, Animal; Benzodiazepines; Blood Pressure; Diazepam; Disease Model | 2010 |
[31P]/[1H] nuclear magnetic resonance study of mitigating effects of GYKI 52466 on kainate-induced metabolic impairment in perfused rat cerebrocortical slices.
Topics: Adenosine Triphosphate; Animals; Anti-Anxiety Agents; Anticonvulsants; Aspartic Acid; Benzodiazepine | 1998 |