gw9662 has been researched along with Triple-Negative-Breast-Neoplasms* in 1 studies
1 other study(ies) available for gw9662 and Triple-Negative-Breast-Neoplasms
Article | Year |
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CRISPR-Cas9 Genome-Wide Knockout Screen Identifies Mechanism of Selective Activity of Dehydrofalcarinol in Mesenchymal Stem-like Triple-Negative Breast Cancer Cells.
There are no targeted therapies available for triple-negative breast cancers (TNBCs) in part because they represent a heterogeneous group of tumors with diverse oncogenic drivers. Our goal is to identify targeted therapies for subtypes of these cancers using a mechanism-blind screen of natural product extract libraries. An extract from Topics: 17-Hydroxysteroid Dehydrogenases; Aldehyde Oxidoreductases; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; CRISPR-Cas Systems; Female; Gene Knockout Techniques; Humans; Molecular Structure; Neoplastic Stem Cells; PPAR gamma; RNA, Small Interfering; Triple Negative Breast Neoplasms | 2020 |