gw-803430 and Body-Weight

gw-803430 has been researched along with Body-Weight* in 1 studies

Other Studies

1 other study(ies) available for gw-803430 and Body-Weight

Article	Year
The discovery and optimization of pyrimidinone-containing MCH R1 antagonists. Bioorganic & medicinal chemistry letters, 2006, Sep-15, Volume: 16, Issue:18 Optimization of a series of constrained melanin-concentrating hormone receptor 1 (MCH R1) antagonists has provided compounds with potent and selective MCH R1 activity. Details of the optimization process are provided and the use of one of the compounds in an animal model of diet-induced obesity is presented. Topics: Animals; Body Weight; Mice; Mice, Inbred AKR; Models, Molecular; Molecular Structure; Pyrimidinones; Receptors, Pituitary Hormone; Structure-Activity Relationship; Sulfhydryl Compounds	2006

Article

Year

The discovery and optimization of pyrimidinone-containing MCH R1 antagonists.

Bioorganic & medicinal chemistry letters, 2006, Sep-15, Volume: 16, Issue:18

Optimization of a series of constrained melanin-concentrating hormone receptor 1 (MCH R1) antagonists has provided compounds with potent and selective MCH R1 activity. Details of the optimization process are provided and the use of one of the compounds in an animal model of diet-induced obesity is presented.

Topics: Animals; Body Weight; Mice; Mice, Inbred AKR; Models, Molecular; Molecular Structure; Pyrimidinones; Receptors, Pituitary Hormone; Structure-Activity Relationship; Sulfhydryl Compounds

2006