gw-311616 and Bacterial-Infections

gw-311616 has been researched along with Bacterial-Infections* in 1 studies

Other Studies

1 other study(ies) available for gw-311616 and Bacterial-Infections

Article	Year
The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase--GW311616A a development candidate. Bioorganic & medicinal chemistry letters, 2001, Apr-09, Volume: 11, Issue:7 The discovery of a potent intracellular inhibitor of human neutrophil elastase which is orally active and has a long duration of action is described. The pharmacodynamic and pharmacokinetic properties of a trans-lactam development candidate, GW311616A, are described. Topics: Administration, Oral; Animals; Bacteria; Bacterial Infections; Biological Availability; Cricetinae; Crystallization; Dogs; Drug Stability; Lactams; Leukocyte Elastase; Metabolic Clearance Rate; Pancreatic Elastase; Piperidines; Rats; Serine Endopeptidases; Serpins	2001

Article

Year

The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase--GW311616A a development candidate.

Bioorganic & medicinal chemistry letters, 2001, Apr-09, Volume: 11, Issue:7

The discovery of a potent intracellular inhibitor of human neutrophil elastase which is orally active and has a long duration of action is described. The pharmacodynamic and pharmacokinetic properties of a trans-lactam development candidate, GW311616A, are described.

Topics: Administration, Oral; Animals; Bacteria; Bacterial Infections; Biological Availability; Cricetinae; Crystallization; Dogs; Drug Stability; Lactams; Leukocyte Elastase; Metabolic Clearance Rate; Pancreatic Elastase; Piperidines; Rats; Serine Endopeptidases; Serpins

2001