Page last updated: 2024-08-23

gusperimus and Graft vs Host Disease

gusperimus has been researched along with Graft vs Host Disease in 21 studies

*Graft vs Host Disease: The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION. [MeSH]

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19904 (19.05)18.7374
1990's15 (71.43)18.2507
2000's2 (9.52)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Annat, J; Derrepas, P; Dutartre, P; Lebreton, L; Renaut, P1
Annat, J; Carboni, B; Dutartre, P; Jost, E; Lebreton, L; Renaut, P; Vaultier, M1
Gannedahl, G; Tufveson, G1
Higa, T; Kasai, M; Kiyama, Y; Masauzi, N; Matsuura, A; Morii, K; Naohara, T; Ohizumi, H; Tanaka, J; Watanabe, M1
Fändrich, F; Jacob, S; Schröder, J; Schroeder, P; Schweizer, E; Waaga, AM1
Appelbaum, FR; Deeg, HJ; Graham, T; Pepe, M; Raff, RF; Sale, GE; Schaffer, R; Schuening, F; Storb, R1
Reich, S; Slavin, S; Weiss, L1
Eckstein, V; Fändrich, F; Herwartz, C; Krzymanski, M; Muller-Ruchholtz, W; Russell, ME; Waaga, AM1
Fändrich, F; Jahnke, T; Pawaresch, MR; Schröder, J; Waaga, AM; Wacker, HH1
Imai, Y; Moizumi, Y; Sakurai, M; Tabayashi, K; Uchida, S1
Clancy, J; Goral, J; Mathews, HL; Nadler, SG1
Makabe, M; Orita, K; Tanaka, S1
Simpson, D1
Fujioka, M; Makabe, M; Okada, H; Orita, K; Orita, T; Tanaka, S; Uda, K1
Abe, F; Fujii, A; Hayashi, M; Mae, T; Nemoto, K; Sugawara, Y; Takeuchi, T1
Abe, F; Fujii, A; Fujii, H; Hayashi, M; Ito, J; Mae, T; Nemoto, K; Sugawara, Y; Takeuchi, T1
Hiraoka, A1
Abe, F; Hayashi, M; Nemoto, K; Takeuchi, T; Takita, T1
Fujii, H; Hayashi, M; Ito, J; Nakamura, T; Nemoto, K; Takeuchi, T; Umezawa, H1
Dickneite, G; Schorlemmer, HU; Sedlacek, HH1
Abe, F; Hayashi, M; Ito, J; Nakamura, T; Nemoto, K; Ohtaka, Y; Takeuchi, T; Umezawa, H1

Reviews

2 review(s) available for gusperimus and Graft vs Host Disease

ArticleYear
Deoxyspergualin--a different and intriguing immunosuppressant.
    Transplantation proceedings, 1994, Volume: 26, Issue:5

    Topics: Animals; Autoimmune Diseases; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Graft Rejection; Graft vs Host Disease; Guanidines; Humans; Immunosuppressive Agents; Islets of Langerhans Transplantation; Transplantation Immunology; Transplantation, Heterologous; Transplantation, Homologous

1994
New developments in the prophylaxis and treatment of graft versus host disease.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:7

    Topics: Abatacept; Alemtuzumab; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antigens, CD; Antigens, Differentiation; Antimetabolites; Bone Marrow Transplantation; CD40 Ligand; Clinical Trials as Topic; CTLA-4 Antigen; Cyclosporine; Drug Design; Graft vs Host Disease; Guanidines; Guidelines as Topic; Humans; Immunoconjugates; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Transplantation; Methotrexate; Mycophenolic Acid; Sirolimus; T-Lymphocytes; Tacrolimus

2001

Other Studies

19 other study(ies) available for gusperimus and Graft vs Host Disease

ArticleYear
Structure-immunosuppressive activity relationships of new analogues of 15-deoxyspergualin. 1. Structural modifications of the hydroxyglycine moiety.
    Journal of medicinal chemistry, 1999, Jan-28, Volume: 42, Issue:2

    Topics: Animals; Glycine; Graft vs Host Disease; Guanidines; Heart Transplantation; Immunosuppressive Agents; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Rats; Structure-Activity Relationship; Transplantation, Homologous

1999
Structure-immunosuppressive activity relationships of new analogues of 15-deoxyspergualin. 2. Structural modifications of the spermidine moiety.
    Journal of medicinal chemistry, 1999, Nov-18, Volume: 42, Issue:23

    Topics: Animals; Carbamates; Drug Evaluation, Preclinical; Graft vs Host Disease; Guanidines; Heart Transplantation; Immunosuppressive Agents; Mice; Rats; Rats, Inbred Lew; Spermidine; Stereoisomerism; Structure-Activity Relationship; Transplantation, Homologous

1999
15-Deoxyspergualin controls cyclosporin- and steroid-resistant intestinal acute graft-versus-host disease after allogeneic bone marrow transplantation.
    Bone marrow transplantation, 1994, Volume: 14, Issue:2

    Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Bone Marrow Transplantation; Cyclosporine; Drug Resistance; Graft vs Host Disease; Guanidines; Humans; Immunosuppressive Agents; Intestinal Diseases; Male; Transplantation, Homologous

1994
Impact of 15-deoxyspergualin on MHC class I and II antigen expression following small bowel transplantation in rats.
    Transplantation proceedings, 1994, Volume: 26, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Antibody Formation; Graft vs Host Disease; Guanidines; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Immunity, Cellular; Immunosuppressive Agents; Intestine, Small; Liver; Lymph Nodes; Macrophages; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Spleen; T-Lymphocytes; Transplantation, Heterotopic; Transplantation, Homologous

1994
What role for 15-deoxyspergualin in enhancing engraftment of unrelated, histoincompatible canine marrow grafts and preventing graft-versus-host disease?
    Transplantation, 1993, Volume: 55, Issue:3

    Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Dogs; Graft Survival; Graft vs Host Disease; Guanidines; Histocompatibility; HLA-A Antigens; HLA-B Antigens; Immunosuppressive Agents; Time Factors; Whole-Body Irradiation

1993
Effect of deoxyspergualin on graft-versus-host disease and graft- versus-leukemia in mice.
    Bone marrow transplantation, 1996, Volume: 17, Issue:5

    Topics: Animals; Bone Marrow Transplantation; Graft Survival; Graft vs Host Disease; Guanidines; Immunosuppressive Agents; Leukemia, B-Cell; Leukemia, Experimental; Lymphocyte Depletion; Major Histocompatibility Complex; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Minor Histocompatibility Antigens; T-Lymphocytes; Transplantation, Homologous

1996
15-deoxyspergualin downregulates MHC class II antigen expression and cell migration in models of graft-versus-host and host-versus-graft disease.
    Transplantation proceedings, 1996, Volume: 28, Issue:5

    Topics: Animals; Gene Expression Regulation; Genes, MHC Class II; Graft vs Host Disease; Guanidines; Histocompatibility Antigens Class II; Host vs Graft Reaction; Immunosuppressive Agents; Inflammation; Intestine, Small; Lymph Nodes; Male; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Spleen; Transplantation, Heterotopic; Transplantation, Homologous

1996
Migration and activation pattern of specialized dendritic cells after heterotopic small bowel transplantation in a graft-versus-host model of the rat.
    Frontiers in bioscience : a journal and virtual library, 1997, Jan-01, Volume: 2

    Topics: Animals; Antigen-Presenting Cells; Cell Movement; Dendritic Cells, Follicular; Disease Models, Animal; Female; Flow Cytometry; Graft Survival; Graft vs Host Disease; Guanidines; Immunosuppressive Agents; Intestine, Small; Lymph Nodes; Lymphatic Vessels; Male; Rats; Rats, Inbred Dahl; Rats, Inbred Lew; T-Lymphocytes; Transplantation, Heterotopic; Transplantation, Isogeneic

1997
Transfusion-associated graft-versus-host disease in immunocompetent patient: early diagnosis and therapy.
    American journal of hematology, 1998, Volume: 58, Issue:1

    Topics: Aged; Aortic Aneurysm; Aortic Dissection; Cyclosporine; DNA; Glucocorticoids; Graft vs Host Disease; Guanidines; Humans; Immunocompetence; Immunosuppressive Agents; Male; Methylprednisolone; Microsatellite Repeats; Polymorphism, Genetic; Time Factors; Transfusion Reaction

1998
Reduced levels of Hsp70 result in a therapeutic effect of 15-deoxyspergualin on acute graft-versus-host disease in (DA x LEW)F1 rats.
    Immunobiology, 2000, Volume: 202, Issue:3

    Topics: Acute Disease; Animals; Cells, Cultured; Female; Graft vs Host Disease; Guanidines; HSP70 Heat-Shock Proteins; Immunosuppressive Agents; Interferon-gamma; Interleukin-10; Interleukin-2; Interleukin-4; Lymph Nodes; Male; Morbidity; Rats; Rats, Inbred Lew; Spleen; Tumor Necrosis Factor-alpha

2000
The effect of deoxyspergualin (DSG) on rejection and graft-versus-host disease (GVHD) after small bowel transplantation.
    Transplant international : official journal of the European Society for Organ Transplantation, 1994, Volume: 7 Suppl 1

    Topics: Animals; Crosses, Genetic; Cytotoxicity, Immunologic; Graft Rejection; Graft Survival; Graft vs Host Disease; Guanidines; Humans; Immunosuppressive Agents; Intestine, Small; K562 Cells; Killer Cells, Natural; Male; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Transplantation, Heterotopic; Transplantation, Homologous

1994
Mechanism of graft-versus-host disease and inhibition with deoxyspergualin on small bowel transplantation in rats.
    Transplantation proceedings, 1992, Volume: 24, Issue:3

    Topics: Animals; Cell Line; Crosses, Genetic; Cytotoxicity, Immunologic; Graft vs Host Disease; Guanidines; Humans; Immunosuppressive Agents; Intestine, Small; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Spleen; Transplantation, Heterotopic; Transplantation, Homologous; Transplantation, Isogeneic

1992
Immunological unresponsiveness by deoxyspergualin therapy in mice undergoing lethal graft-vs-host disease, and successful adoptive transfer of unresponsiveness.
    Transplantation proceedings, 1991, Volume: 23, Issue:1 Pt 1

    Topics: Animals; Bone Marrow Transplantation; Female; Graft vs Host Disease; Guanidines; Immunosuppression Therapy; Immunosuppressive Agents; Immunotherapy, Adoptive; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Spleen

1991
Deoxyspergualin in lethal murine graft-versus-host disease.
    Transplantation, 1991, Volume: 51, Issue:3

    Topics: Animals; Antigens, Surface; Bone Marrow Transplantation; Drug Therapy, Combination; Female; Graft Survival; Graft vs Host Disease; Guanidines; Histocompatibility Testing; Immunosuppressive Agents; Killer Cells, Natural; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred Strains; Spleen; T-Lymphocytes, Cytotoxic

1991
[Control of graft-vs-host disease].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1990, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Female; Graft vs Host Disease; Guanidines; Humans; Leucine; Leukemia; Male; Methylprednisolone; Ribonucleosides

1990
Inhibition by deoxyspergualin of allo-reactive cytotoxic activity in mouse graft-versus-host disease.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 3

    Topics: Animals; Bone Marrow Transplantation; Cytotoxicity, Immunologic; Female; Graft vs Host Disease; Guanidines; Immunosuppressive Agents; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Postoperative Complications; Transplantation, Homologous

1989
Effect of 15-deoxyspergualin on graft-v-host disease in mice.
    Transplantation proceedings, 1987, Volume: 19, Issue:5

    Topics: Animals; Bone Marrow Transplantation; Graft vs Host Disease; Guanidines; Immunosuppressive Agents; Mice; Mice, Inbred Strains; Spleen

1987
[Preclinical results with 15-deoxyspergualin in experimental graft versus host disease].
    Immunitat und Infektion, 1988, Volume: 16, Issue:1

    Topics: Anemia, Hemolytic; Animals; Antibiotics, Antineoplastic; Disease Models, Animal; Glomerulonephritis; Graft vs Host Disease; Guanidines; Mice; Mice, Inbred DBA; Mice, Inbred Strains

1988
Effects of spergualin and 15-deoxyspergualin on the development of graft-versus-host disease in mice.
    Transplantation proceedings, 1987, Volume: 19, Issue:4

    Topics: Animals; Female; Graft vs Host Disease; Guanidines; Immunosuppressive Agents; Mice

1987