Page last updated: 2024-08-23

gusperimus and Diabetes Mellitus, Type 1

gusperimus has been researched along with Diabetes Mellitus, Type 1 in 22 studies

Research

Studies (22)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	21 (95.45)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (4.55)	2.80

Authors

Authors	Studies
de Haan, BJ; de Vos, P; Faas, MM; López, BL; Navarro Chica, CE; Pinheiro-Machado, E; Qin, T; Sierra, L; Smink, AM	1
Ansite, JD; Lokeh, A; Mills, CD; Rossini, TJ; Stevens, RB; Sutherland, DE	1
Ljung, T; Pittman, K; Thomas, FT	1
Bretzel, RG; Federlin, K; Geier, C; Groth, CG; Hering, BJ	1
Gannedahl, G; Tufveson, G	1
Henretta, J; McFadden, T; Pittman, K; Thomas, F	1
Gores, PF; Kelley, SL; Lloveras, JJ; Najarian, JS; Stephanian, E; Sutherland, DE	2
Ansite, JD; Brayman, K; Gores, PF; Jessurun, J; Lokeh, A; Stevens, RB; Sutherland, DE; Tepper, M	1
Andersson, A; Groth, CG; Hellerström, C; Korsgren, O; Möller, E; Tibell, A	1
Dickneite, G; Schorlemmer, HU	1
Barcellini, W; Borghi, MO; Bruno, G; Di Marco, R; Fain, C; Magro, G; Menta, R; Meroni, PL; Nicoletti, F; Schorlemmer, HU	1
Pittman, K; Thomas, FT; Thomas, JM	1
Aasheim, T; Gilmore, T; Leone, J; Papalois, B; Sutherland, DE; Wahoff, D	1
Barcellini, W; Di Marco, R; Grasso, S; Lunetta, M; Magro, G; Meroni, PL; Nicoletti, F; Nicolosi, VM; Zaccone, P	1
Haberstroh, J; Schorlemmer, HU; Schulte-Mönting, J; von Specht, BU; Wilhelm, T	1
Coulombe, M; Gill, RG; Loberman, Z; Ostrowska, A; Stegall, MD	1
Brandhorst, D; Brandhorst, H; Bretzel, RG; Federlin, K; Hering, BJ; Hopt, UT; Liu, X; Mellert, J	1
Chatzipetrou, M; Kenyon, NS; Masetti, M; Ranuncoli, A; Ricordi, C	1
Sandler, S; Strandell, E	1
Amemiya, H; Aomatsu, Y; Fukuoka, T; Hisanaga, M; Iwata, H; Kanehiro, H; Nakajima, Y; Nakano, H; Takagi, T	1
Barcellini, W; Borghi, MO; Di Marco, R; Grasso, S; Lunetta, M; Menta, R; Meroni, PL; Mughini, L; Nicoletti, F; Schorlemmer, HU	1

Reviews

3 review(s) available for gusperimus and Diabetes Mellitus, Type 1

Article	Year
Deoxyspergualin--a different and intriguing immunosuppressant. Transplantation proceedings, 1994, Volume: 26, Issue:5 Topics: Animals; Autoimmune Diseases; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Graft Rejection; Graft vs Host Disease; Guanidines; Humans; Immunosuppressive Agents; Islets of Langerhans Transplantation; Transplantation Immunology; Transplantation, Heterologous; Transplantation, Homologous	1994
Preclinical studies with 15-deoxyspergualin in various animal models for autoimmune diseases. Annals of the New York Academy of Sciences, 1993, Jun-23, Volume: 685 Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Autoimmune Diseases; Diabetes Mellitus, Type 1; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Guanidines; Lupus Erythematosus, Systemic; Mice; Nephritis; Rats	1993
Islet transplantation: present and future perspectives. Diabetes/metabolism reviews, 1998, Volume: 14, Issue:4 Topics: Clinical Trials as Topic; Cyclosporine; Diabetes Mellitus, Type 1; Graft Rejection; Guanidines; Humans; Immunosuppressive Agents; Islets of Langerhans Transplantation; Tacrolimus; Tissue Donors	1998

Trials

1 trial(s) available for gusperimus and Diabetes Mellitus, Type 1

Article	Year
Insulin independence in type I diabetes after transplantation of unpurified islets from single donor with 15-deoxyspergualin. Lancet (London, England), 1993, Jan-02, Volume: 341, Issue:8836 Topics: Adult; Antilymphocyte Serum; Azathioprine; Creatinine; Cyclosporine; Diabetes Mellitus, Type 1; Female; Guanidines; Humans; Immunosuppressive Agents; Insulin; Islets of Langerhans Transplantation; Kidney Transplantation; Male; Prednisone; Tissue Donors	1993

Article

Year

Insulin independence in type I diabetes after transplantation of unpurified islets from single donor with 15-deoxyspergualin.

Lancet (London, England), 1993, Jan-02, Volume: 341, Issue:8836

Topics: Adult; Antilymphocyte Serum; Azathioprine; Creatinine; Cyclosporine; Diabetes Mellitus, Type 1; Female; Guanidines; Humans; Immunosuppressive Agents; Insulin; Islets of Langerhans Transplantation; Kidney Transplantation; Male; Prednisone; Tissue Donors

1993

Other Studies

18 other study(ies) available for gusperimus and Diabetes Mellitus, Type 1

Article	Year
Species-dependent impact of immunosuppressive squalene-gusperimus nanoparticles and adipose-derived stem cells on isolated human and rat pancreatic islets. Islets, 2022, 12-31, Volume: 14, Issue:1 Topics: Animals; Diabetes Mellitus, Type 1; Guanidines; Humans; Immunosuppressive Agents; Islets of Langerhans; Islets of Langerhans Transplantation; Nanoparticles; Rats; Squalene; Stem Cells	2022
15-Deoxyspergualin inhibits nitric oxide production in the BB/W rat: mechanism for inhibition of islet cell dysfunction in diabetes and transplantation. Transplantation proceedings, 1994, Volume: 26, Issue:6 Topics: Amino Acid Oxidoreductases; Animals; Concanavalin A; Diabetes Mellitus, Type 1; Enzyme Induction; Guanidines; Immunosuppressive Agents; Islets of Langerhans; Islets of Langerhans Transplantation; Lymphocyte Activation; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Polymerase Chain Reaction; Rats; Rats, Inbred BB; Rats, Inbred F344; RNA, Messenger; Spleen; T-Lymphocytes	1994
Successful long-term pancreatic islet cell xenotransplantation and functional tolerance in NOD mice. Transplantation proceedings, 1995, Volume: 27, Issue:1 Topics: Animals; Antilymphocyte Serum; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Type 1; Guanidines; Immunosuppressive Agents; Islets of Langerhans; Islets of Langerhans Transplantation; Mice; Mice, Inbred NOD; Swine; Transplantation, Heterologous	1995
Immunosuppression in pancreatic islet cell transplantation. Transplantation proceedings, 1994, Volume: 26, Issue:5 Topics: Antilymphocyte Serum; Azathioprine; Cyclosporine; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Guanidines; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Islets of Langerhans Transplantation; Kidney Transplantation; Prednisolone; Retrospective Studies	1994
Successful discordant pancreatic islet xenotransplantation by prevention of primary nonfunction graft rejection and autoimmune disease recurrence. Transplantation proceedings, 1994, Volume: 26, Issue:3 Topics: Animals; Antilymphocyte Serum; Blood Glucose; Diabetes Mellitus, Type 1; Graft Rejection; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Mice; Mice, Inbred NOD; Rabbits; Recurrence; Swine; Transplantation, Heterologous; Transplantation, Heterotopic	1994
Transplantation of unpurified islets from single donors with 15-deoxyspergualin. Transplantation proceedings, 1994, Volume: 26, Issue:2 Topics: C-Peptide; Cell Separation; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Follow-Up Studies; Glycated Hemoglobin; Guanidines; Humans; Immunosuppressive Agents; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Time Factors	1994
Role of 15-deoxyspergualin in the prevention of diabetes in the BB/w rat. Transplantation proceedings, 1994, Volume: 26, Issue:2 Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Guanidines; Hyperglycemia; Immunosuppressive Agents; Prediabetic State; Rats; Rats, Inbred BB	1994
Pig-to-human islet transplantation in eight patients. Transplantation proceedings, 1994, Volume: 26, Issue:2 Topics: Animals; Antilymphocyte Serum; C-Peptide; Diabetes Mellitus, Type 1; Fetal Tissue Transplantation; Follow-Up Studies; Guanidines; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Islets of Langerhans Transplantation; Swine; Time Factors; Transplantation, Heterologous; Treatment Outcome	1994
Prevention of cyclophosphamide-induced diabetes in the NOD/WEHI mouse with deoxyspergualin. Clinical and experimental immunology, 1993, Volume: 91, Issue:2 Topics: Animals; Autoimmune Diseases; Cyclophosphamide; Diabetes Mellitus, Type 1; Female; Guanidines; Immunosuppressive Agents; Interferon-gamma; Mice; Mice, Inbred CBA; Mice, Inbred NOD; Receptors, Interleukin-2	1993
Induction of functional xenograft tolerance of pig islets in the autoimmune NOD mouse. Transplantation proceedings, 1995, Volume: 27, Issue:6 Topics: Animals; Antilymphocyte Serum; Blood Glucose; Diabetes Mellitus, Type 1; Graft Survival; Guanidines; Immune Tolerance; Immunosuppression Therapy; Immunosuppressive Agents; Islets of Langerhans Transplantation; Mice; Mice, Inbred NOD; Swine; Transplantation, Heterologous	1995
The effect of 15-deoxyspergualin on islet allograft survival in the canine model. Transplantation proceedings, 1996, Volume: 28, Issue:2 Topics: Animals; Antilymphocyte Serum; Azathioprine; Cyclosporine; Diabetes Mellitus, Type 1; Dogs; Drug Therapy, Combination; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Pancreatectomy; Transplantation, Autologous; Transplantation, Homologous	1996
Synergistic effect of deoxyspergualin (DSP) and cyclosporin A (CsA) in the prevention of spontaneous autoimmune diabetes in BB rats. Clinical and experimental immunology, 1996, Volume: 105, Issue:2 Topics: Animals; Cyclosporine; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Drug Synergism; Female; Guanidines; Immunosuppressive Agents; Male; Rats; Rats, Inbred BB	1996
Prevention of type I diabetes in the non-obese diabetic (NOD) mouse with 15-deoxyspergualin (15-DS) or 15-DS + cyclosporin A (CyA). Immunology letters, 1995, Volume: 48, Issue:2 Topics: Animals; Cyclosporine; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Female; Guanidines; Hypoglycemic Agents; Immunosuppressive Agents; Male; Mice; Mice, Inbred NOD; Random Allocation	1995
Autoimmune destruction of islet grafts in the NOD mouse is resistant to 15-deoxyspergualin but sensitive to anti-CD4 antibody. The Journal of surgical research, 1996, Volume: 64, Issue:2 Topics: Animals; Antibodies, Monoclonal; Autoimmune Diseases; CD4 Antigens; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Graft Rejection; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Streptozocin	1996
Prevention of primary nonfunction after porcine islet allotransplantation. Transplantation proceedings, 1997, Volume: 29, Issue:4 Topics: Animals; Antilymphocyte Serum; Blood Glucose; Diabetes Mellitus, Type 1; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Pancreatectomy; Swine; Transplantation, Homologous	1997
Protection against hyperglycemia in female nonobese diabetic mice treated with 15-deoxyspergualin. Autoimmunity, 1992, Volume: 14, Issue:2 Topics: Age Factors; Animals; Cell Count; Cell Division; Cells, Cultured; Cyclophosphamide; Diabetes Mellitus, Type 1; Female; Guanidines; Hyperglycemia; Immunosuppressive Agents; Inflammation; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred NOD; Spleen; T-Lymphocyte Subsets	1992
Microencapsulated islets in agarose gel as bioartificial pancreas for discordant xenotransplantation. Transplantation proceedings, 1992, Volume: 24, Issue:6 Topics: Animals; Blood Glucose; Capsules; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diffusion Chambers, Culture; Dogs; Graft Rejection; Graft Survival; Guanidines; Immunosuppressive Agents; Insulin; Insulin Secretion; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Sepharose; Transplantation, Heterologous	1992
The effects of deoxyspergualin on the development of diabetes in diabetes-prone BB rats. Scandinavian journal of immunology, 1992, Volume: 36, Issue:3 Topics: Animals; Diabetes Mellitus, Type 1; Female; Flow Cytometry; Follow-Up Studies; Guanidines; Immunosuppressive Agents; Islets of Langerhans; Male; Rats; Rats, Inbred BB; Spleen	1992