gusperimus has been researched along with Alloxan Diabetes in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (17.24) | 18.7374 |
| 1990's | 21 (72.41) | 18.2507 |
| 2000's | 3 (10.34) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hsu, BR; Juang, JH; Kuo, CH | 1 |
| Bilbao, G; Contreras, JL; Eckhoff, DE; Hubbard, WJ; Jenkins, S; Lobashevsky, A; Neville, DM; Thomas, FT; Thomas, JM | 1 |
| Chang, CY; Joh, JW; Jung, DY; Kim, EY; Kim, SJ; Kwon, GY; Lee, EN; Lee, HJ; Lee, J; Lee, SK; Park, HJ | 1 |
| Amemiya, H; Aomatsu, Y; Hisanaga, M; Horikawa, M; Iwata, H; Kanehiro, H; Kido, K; Nakajima, Y; Taki, J; Yoshimura, A | 1 |
| Kearns, H; Wright, JR | 1 |
| Borel, JF; Lu, X | 1 |
| Cekada, E; Ljung, T; Pittman, K; Thomas, F | 1 |
| Aomatsu, Y; Kanehiro, H; Nakajima, Y; Nakano, H; Yoshimura, A | 1 |
| Beer, E; Cho, SI; Jindal, RM; Soltys, K; Tepper, MA; Yost, F | 1 |
| Henretta, J; McFadden, T; Pittman, K; Thomas, F; Thomas, J | 2 |
| Henretta, J; McFadden, T; Pittman, K; Thomas, FT; Thomas, J | 1 |
| Chou, TC; Field, JF; Gores, PF; Sutherland, DE | 1 |
| Farney, AC; Field, MJ; Gores, PF; Gruber, SA; Kaufman, DB; Stephanian, E; Sutherland, DE | 2 |
| Andersson, A; Groth, CG; Korsgren, O; Sandberg, JO | 1 |
| Andereggen, E; Bubloz, C; Bühler, L; Deng, S; Fournier, B; Morel, P | 1 |
| Fiedor, PS; Goodman, ER; Hardy, MA; Quadracci, KM; Sung, RS; Yaron, I; Zakheim, AR | 1 |
| Gruessner, AC; Gruessner, RW; Matas, AJ; Moon, C; Nakhleh, RE; Papalois, BE; Sehgal, SN; Troppmann, C | 1 |
| Kanehiro, H; Nakajima, Y; Nakano, H; Yoshimura, A | 1 |
| Hisanaga, M; Nakajima, Y; Nakano, H; Segawa, M; Ueno, M; Yabuuchi, H; Yoshimura, A | 1 |
| Hisanaga, M; Nakajima, Y; Nakano, H; Yabuuchi, H | 1 |
| Amemiya, H; Aomatsu, Y; Fukuoka, T; Hisanaga, M; Iwata, H; Kanehiro, H; Nakajima, Y; Nakano, H; Takagi, T | 1 |
| Hisanaga, M; Kanehiro, H; Murao, Y; Nakagawa, K; Nakajima, Y; Nakano, H; Segawa, M; Wada, T; Yabuuchi, H; Yoshimura, A | 1 |
| Loske, G; Schang, T; Schubert, G; Stoffregen, C; Thiede, A; Timmermann, W | 1 |
| Dibelius, A; Königsberger, H; Lodde, G; Permanetter, W; Roth, H; von Specht, BU | 1 |
| Andersson, A; Groth, CG; Sandler, S; Strandell, E | 1 |
| Dickneite, G; Feifel, G; Keller, HE; Sedlacek, HH; Thies, JC; Walter, PK; Zimmermann, FA | 1 |
| Nakamura, T; Nemoto, K; Sugawara, Y; Takeuchi, T; Takita, T | 1 |
29 other study(ies) available for gusperimus and Alloxan Diabetes
| Article | Year |
|---|---|
15-Deoxyspergualin protects the islet graft from macrophage-mediated injury.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Macrophages; Male; Mice; Mice, Inbred C57BL; Time Factors; Transplantation, Isogeneic | 2002 |
Stable alpha- and beta-islet cell function after tolerance induction to pancreatic islet allografts in diabetic primates.
Topics: Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Graft Rejection; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Macaca mulatta; Male; Reference Values; Transplantation Tolerance; Treatment Outcome | 2003 |
Beneficial effects of simultaneous treatment with 15-deoxyspergualin and monoclonal antibodies to CD45RB and CD154 on murine islet transplantation recipients.
Topics: Animals; Antibodies, Monoclonal; CD40 Ligand; Cytokines; Diabetes Mellitus, Experimental; Flow Cytometry; Guanidines; Immune Tolerance; Immunosuppressive Agents; Islets of Langerhans Transplantation; Leukocyte Common Antigens; Male; Mice; Mice, Inbred BALB C; Rats; T-Lymphocytes; Transplantation, Heterologous; Transplantation, Homologous | 2006 |
Significance of low doses of 15-deoxyspergualin in agarose-microencapsulated discordant islet xenotransplantation.
Topics: Animals; Antibodies; Blood Glucose; Capsules; Diabetes Mellitus, Experimental; Dogs; Flow Cytometry; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Sepharose; Time Factors; Transplantation, Heterologous | 1995 |
Fish-to-mouse islet xenograft survival is markedly prolonged by 15-deoxyspergualin.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Graft Rejection; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Male; Mice; Mice, Inbred BALB C; Tilapia; Time Factors; Transplantation, Heterologous | 1995 |
Prolongation of islet xenograft survival with combined treatment of 15-deoxyspergualin or cyclosporine and anti-CD4 monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; CD4 Antigens; Cells, Cultured; Combined Modality Therapy; Cricetinae; Cyclosporine; Diabetes Mellitus, Experimental; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans; Islets of Langerhans Transplantation; Mesocricetus; Mice; Mice, Inbred CBA; Transplantation, Heterologous | 1995 |
Deoxyspergualin is a unique immunosuppressive agent with selective utility in inducing tolerance to pancreas islet xenografts.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Graft Survival; Guanidines; Immunosuppression Therapy; Immunosuppressive Agents; Inflammation; Insulin; Islets of Langerhans Transplantation; Rats; Rats, Inbred Lew; Swine; Transplantation, Heterologous | 1995 |
Mode of action of 15-deoxyspergualin in xenografting islets of Langerhans.
Topics: Animals; Cricetinae; Cytotoxicity, Immunologic; Diabetes Mellitus, Experimental; Graft Rejection; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Male; Mesocricetus; Rats; Rats, Wistar; Time Factors; Transplantation, Heterologous | 1994 |
Xenotransplantation of pig pancreatic islets to rat using 15-deoxyspergualin monotherapy.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Male; Rats; Rats, Wistar; Swine; Time Factors; Transplantation, Heterologous | 1994 |
Six- to eight-month survival of discordant pig islet xenografts documented by differential species, insulin, and C-peptide in animals given short-term immunosuppression.
Topics: Animals; Antilymphocyte Serum; Blood Glucose; Cell Separation; Diabetes Mellitus, Experimental; Graft Survival; Guanidines; Immunosuppression Therapy; Immunosuppressive Agents; Islets of Langerhans; Islets of Langerhans Transplantation; Lymphoid Tissue; Rats; Rats, Inbred Lew; Swine; Transplantation, Heterologous; Whole-Body Irradiation | 1994 |
Prevention of primary nonfunction of xenograft islets.
Topics: Animals; Antilymphocyte Serum; Blood Glucose; Diabetes Mellitus, Experimental; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Rats; Rats, Inbred Lew; Swine; Transplantation, Heterologous | 1994 |
Synergistic interaction of 15-deoxyspergualin and cyclosporine to prolong the survival of rat islet allografts.
Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Drug Synergism; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Rats; Rats, Inbred Lew; Rats, Inbred WF; Regression Analysis; Transplantation, Homologous | 1994 |
Effect of 15-deoxyspergualin on immediate function and long-term survival of transplanted islets in murine recipients of a marginal islet mass.
Topics: Animals; Blood Glucose; Cell Survival; Diabetes Mellitus, Experimental; Guanidines; Hyperglycemia; Immunosuppressive Agents; Islets of Langerhans; Islets of Langerhans Transplantation; Lymphocyte Transfusion; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Transplantation, Homologous; Transplantation, Isogeneic | 1994 |
15-Deoxyspergualin prolongs pancreatic islet allo- and xenograft survival in mice.
Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Graft Rejection; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Mice; Mice, Inbred C57BL; Transplantation, Heterologous; Transplantation, Homologous | 1993 |
Deoxyspergualin and rabbit antithymocyte globulin markedly prolong discordant pig pancreatic islet xenografts.
Topics: Animals; Antilymphocyte Serum; Blood Glucose; Diabetes Mellitus, Experimental; Guanidines; Immunosuppression Therapy; Immunosuppressive Agents; Islets of Langerhans Transplantation; Rabbits; Rats; Rats, Inbred Lew; Swine; Transplantation, Heterologous | 1993 |
Immunohistological study of islet xenograft rejection in immunosuppressed recipients.
Topics: Animals; CD3 Complex; CD4 Antigens; CD8 Antigens; Cyclosporine; Diabetes Mellitus, Experimental; Graft Rejection; Graft Survival; Guanidines; Immunoglobulins; Immunohistochemistry; Immunosuppressive Agents; Islets of Langerhans Transplantation; Macrophage-1 Antigen; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-2; Tacrolimus; Transplantation, Heterologous | 1996 |
Survival of human islet xenografts irradiated with ultraviolet B in diabetic rats.
Topics: Animals; Antilymphocyte Serum; Cells, Cultured; Diabetes Mellitus, Experimental; Graft Rejection; Graft Survival; Guanidines; Humans; Immunosuppressive Agents; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Rats; Rats, Inbred Lew; Tacrolimus; Transplantation, Heterologous; Ultraviolet Rays | 1996 |
Perioperative immunosuppression as a critical determinant of early outcome after discordant xenoislet transplantation: a comparative study.
Topics: Animals; Blood Glucose; Cyclosporine; Diabetes Mellitus, Experimental; Dogs; Drug Administration Schedule; Drug Therapy, Combination; Graft Survival; Guanidines; Immunosuppression Therapy; Immunosuppressive Agents; Islets of Langerhans Transplantation; Polyenes; Rats; Rats, Inbred Lew; Sirolimus; Tacrolimus; Transplantation, Heterologous | 1996 |
Effect of 15-deoxyspergualin in islet xenograft rejection.
Topics: Animals; Antibodies, Heterophile; Antibody Formation; Blood Glucose; Cricetinae; Diabetes Mellitus, Experimental; Graft Rejection; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Male; Mesocricetus; Rats; Rats, Wistar; Reoperation; Transplantation, Heterologous | 1996 |
Immunosuppressive effect in combination therapy of cyclosporine A, FK 506, and 15-deoxyspergualin on pancreatic islet xenotransplantation.
Topics: Animals; Cricetinae; Cyclosporine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Graft Rejection; Graft Survival; Guanidines; Immunosuppression Therapy; Immunosuppressive Agents; Islets of Langerhans Transplantation; Male; Mesocricetus; Rats; Rats, Inbred Strains; T-Lymphocytes; Tacrolimus; Thymus Gland; Transplantation, Heterologous | 1992 |
Successful combination therapy with FK 506 and 15-deoxyspergualin in pancreatic islet xenografting.
Topics: Animals; Antilymphocyte Serum; Blood Glucose; Cricetinae; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Graft Rejection; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Male; Mesocricetus; Rats; Rats, Inbred Strains; Tacrolimus; Time Factors; Transplantation, Heterologous | 1992 |
Microencapsulated islets in agarose gel as bioartificial pancreas for discordant xenotransplantation.
Topics: Animals; Blood Glucose; Capsules; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diffusion Chambers, Culture; Dogs; Graft Rejection; Graft Survival; Guanidines; Immunosuppressive Agents; Insulin; Insulin Secretion; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Sepharose; Transplantation, Heterologous | 1992 |
Extended functional survival of murine islet allografts with 15-deoxyspergualin.
Topics: Animals; Diabetes Mellitus, Experimental; Graft Rejection; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Transplantation, Homologous; Transplantation, Isogeneic | 1992 |
Prominent prolongation of islet xenograft survival in combination therapy with FK 506 and 15-deoxyspergualin.
Topics: Animals; Anti-Bacterial Agents; Cricetinae; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Graft Survival; Guanidines; Immunosuppressive Agents; Mesocricetus; Rats; Rats, Inbred Strains; Tacrolimus; Thymus Gland; Transplantation, Heterologous | 1991 |
Synergistic effect of 15-deoxyspergualin and cyclosporin A in pancreatic transplantation.
Topics: Animals; Cyclosporins; Diabetes Mellitus, Experimental; Drug Synergism; Drug Therapy, Combination; Duodenum; Graft Rejection; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Pancreas Transplantation; Rats; Rats, Inbred Lew; Rats, Inbred Strains | 1989 |
Prolongation of islet and pancreas graft survival in spontaneous diabetic BB/W rats by perioperative cyclosporin or 15-deoxyspergualin therapy.
Topics: Animals; Blood Glucose; Cyclosporins; Diabetes Mellitus, Experimental; Female; Graft Rejection; Graft Survival; Guanidines; Immunosuppression Therapy; Immunosuppressive Agents; Islets of Langerhans Transplantation; Male; Pancreas Transplantation; Rats; Rats, Inbred BB; Skin Transplantation | 1989 |
Effects of (-)15-deoxyspergualin on pancreatic islet B-cell function in vitro and on the development of diabetes after multiple low dose streptozotocin administration.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Female; Guanidines; Hyperglycemia; Immunosuppressive Agents; Islets of Langerhans; Male; Mice; Streptozocin | 1989 |
Prolongation of graft survival in allogeneic pancreas and liver transplantation by (-)15-deoxyspergualin.
Topics: Animals; Bilirubin; Blood Glucose; Diabetes Mellitus, Experimental; Graft Survival; Guanidines; Immunosuppressive Agents; Liver Transplantation; Male; Pancreas Transplantation; Rats; Rats, Inbred Lew; Time Factors; Transplantation, Homologous; Transplantation, Isogeneic | 1987 |
Assessment of the anti-diabetic activity of deoxyspergualin in low-dose streptozotocin-induced diabetic mice.
Topics: Animals; Cyclosporins; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Guanidines; Immunosuppressive Agents; Male; Mice; Mice, Inbred ICR | 1988 |