guanylthiourea has been researched along with Asphyxia* in 2 studies
2 other study(ies) available for guanylthiourea and Asphyxia
| Article | Year |
|---|---|
[Ultrastructural features of heart insufficiency and its correction during the post-asphyxia period].
The ultrastructure of myocardium was studied in the experiments on rats during 24 hours after 6-min mechanical asphyxia with following clinical death. It has been established that the contractile cardiac apparatus of myocytes lesions on the intracellular edema background is the main while energy production process impairs insignificantly. The effectiveness of anti-hypoxia, membrane stability and protease inhibiting preparations for prevention of postresuscitation myocardium lesion was examined. The contrykal protective action, suppressing the proteolytic ferment hyperactivity was determined. Topics: Animals; Aprotinin; Asphyxia; Coronary Disease; Guanylthiourea; Heart Arrest; Heart Failure; Myocardium; Prednisolone; Rats; Resuscitation | 1990 |
[Comparative study of several preparations in different models of cerebral hypoxia].
The antihypoxic effects of gutimine, piracetam, sodium hydroxybutyrate and lithium hydroxybityrate were studied on different models of brain hypoxia. All the drugs under study produced a remarkable antihypoxic effect in experimental asphyxic hypoxia, increasing brain resistance to oxygen deficiency and rapidly restituting brain function. Drug pretreatment of the animals with carotid artery occlusion raised the number of animals which survived 24 h after the operation. GABA salts appeared the most effective. Sodium hydroxybutyrate increased the lifespan of rats under histotoxic hypoxia. Topics: Animals; Asphyxia; Brain Ischemia; Disease Models, Animal; Drug Evaluation, Preclinical; Electrocardiography; Electroencephalography; Guanylthiourea; Hydroxybutyrates; Hypoxia, Brain; Lithium; Male; Organometallic Compounds; Piracetam; Rats; Sodium Nitrite; Sodium Oxybate | 1984 |