guanosine-triphosphate and Uveitis

guanosine-triphosphate has been researched along with Uveitis* in 1 studies

Other Studies

1 other study(ies) available for guanosine-triphosphate and Uveitis

ArticleYear
The sequence of human retinal S-antigen reveals similarities with alpha-transducin.
    FEBS letters, 1988, Jul-04, Volume: 234, Issue:1

    The complete amino acid sequence of human retinal S-antigen (48 kDa protein), a retinal protein involved in the visual process has been determined by cDNA sequencing. The largest cDNA was 1590 base pairs (bp) and it contained an entire coding sequence. The similarity of nucleotide sequence between the human and bovine is approximately 80%. The predicted amino acid sequence indicates that human S-antigen has 405 residues and its molecular mass is 45050 Da. The amino acid sequence homology between human and bovine is 81%. There is no overall sequence similarity between S-antigen and other proteins listed in the National Biomedical Research Foundation (NBRF) protein data base. However, local regions of sequence homology with alpha-transducin (T alpha) are apparent including the putative rhodopsin binding and phosphoryl binding sites. In addition, human S-antigen has sequences identical to bovine uveitopathogenic sites, indicating that some types of human uveitis may in part be related to the animal model of experimental autoimmune uveitis (EAU).

    Topics: Amino Acid Sequence; Animals; Antigens; Arrestin; Base Sequence; Cattle; Codon; DNA; Eye Proteins; Guanosine Triphosphate; Humans; Membrane Proteins; Molecular Sequence Data; Phosphodiesterase Inhibitors; Sequence Homology, Nucleic Acid; Transducin; Uveitis

1988