guanosine-5--o-(3-thiotriphosphate) and Lymphoma--Non-Hodgkin

guanosine-5--o-(3-thiotriphosphate) has been researched along with Lymphoma--Non-Hodgkin* in 1 studies

Other Studies

1 other study(ies) available for guanosine-5--o-(3-thiotriphosphate) and Lymphoma--Non-Hodgkin

Article	Year
Hormonal regulation of transcription of rDNA: use of nucleoside thiotriphosphates to measure initiation in isolated nuclei. Nucleic acids research, 1984, Nov-12, Volume: 12, Issue:21 Nuclei isolated from cultured mouse and rat cell lines initiated pre-rRNA chains at the correct site and with the correct nucleotide specificity (A for mouse, G for rat). Nucleic acid filter hybridization and S1 nuclease mapping were used to analyze the RNA products initiated with nucleoside (beta-S)triphosphates. Initiation of pre-rRNA was completely resistant to alpha-amanitin but was inhibited by either actinomycin D or heparin. Experiments with P1798 mouse lymphoma cells indicated that the antiproliferative effects of glucocorticoids on lymphoid cells includes a reduction in the ability of nuclei to initiate pre-rRNA chains. Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Nucleus; Dexamethasone; DNA Restriction Enzymes; DNA, Ribosomal; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Experimental; Mice; Nucleic Acid Precursors; Phosphorus Radioisotopes; Plasmids; Rats; RNA Precursors; RNA, Ribosomal; Thionucleotides; Transcription, Genetic; Tritium	1984

Article

Year

Hormonal regulation of transcription of rDNA: use of nucleoside thiotriphosphates to measure initiation in isolated nuclei.

Nucleic acids research, 1984, Nov-12, Volume: 12, Issue:21

Nuclei isolated from cultured mouse and rat cell lines initiated pre-rRNA chains at the correct site and with the correct nucleotide specificity (A for mouse, G for rat). Nucleic acid filter hybridization and S1 nuclease mapping were used to analyze the RNA products initiated with nucleoside (beta-S)triphosphates. Initiation of pre-rRNA was completely resistant to alpha-amanitin but was inhibited by either actinomycin D or heparin. Experiments with P1798 mouse lymphoma cells indicated that the antiproliferative effects of glucocorticoids on lymphoid cells includes a reduction in the ability of nuclei to initiate pre-rRNA chains.

Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Nucleus; Dexamethasone; DNA Restriction Enzymes; DNA, Ribosomal; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Experimental; Mice; Nucleic Acid Precursors; Phosphorus Radioisotopes; Plasmids; Rats; RNA Precursors; RNA, Ribosomal; Thionucleotides; Transcription, Genetic; Tritium

1984