guanidine has been researched along with Uremia in 13 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zounr, RA | 1 |
| Khuhawar, MY | 1 |
| Jahangir, TM | 1 |
| Alamgir, M | 1 |
| CARR, MH | 1 |
| SCHLOERB, PR | 1 |
| OLSEN, NS | 1 |
| BASSETT, JW | 1 |
| Torremans, A | 1 |
| D'Hooge, R | 1 |
| Van de Vijver, G | 1 |
| Marescau, B | 4 |
| Vanholder, R | 1 |
| Lameire, N | 1 |
| De Deyn, PP | 4 |
| Van Bogaert, PP | 1 |
| Tofuku, Y | 1 |
| Kuroda, M | 1 |
| Muramoto, H | 1 |
| Takeda, R | 1 |
| Robitaille, P | 1 |
| Vanasse, M | 1 |
| Qureshi, IA | 1 |
| Dasgupta, A | 1 |
| Malik, S | 1 |
| Sorrentino, R | 1 |
| Sorrentino, L | 1 |
| Pinto, A | 1 |
| Rao, SV | 1 |
| Indira, K | 1 |
| Macdonald, RL | 1 |
| Swartz, RD | 1 |
| Hogaerth, R | 1 |
| Possemiers, I | 1 |
| Lowenthal, A | 2 |
| Ding, WD | 1 |
| Veening, H | 1 |
| Van Effen, RM | 1 |
| De Deyn, P | 1 |
| Lornoy, W | 1 |
| Becaus, I | 1 |
1 trial available for guanidine and Uremia
| Article | Year |
|---|---|
Serum guanidino compound levels in uremic pediatric patients treated with hemodialysis or continuous cycle peritoneal dialysis. Correlations between nerve conduction velocities and altered guanidino compound concentrations.
Topics: Adolescent; Adult; Arginine; Child; Child, Preschool; Creatinine; Female; Guanidine; Guanidines; Hum | 1995 |
12 other studies available for guanidine and Uremia
| Article | Year |
|---|---|
Improved Gas Chromatographic Determination of Guanidino Compounds Using Isovaleroylacetone and Ethyl Chloroformate as Derivatizing Reagents.
Topics: Acetone; Arginine; Boric Acids; Butyrates; Butyric Acid; Calibration; Chromatography, Gas; Creatinin | 2016 |
Analysis for guanidine and methlguanidine in uremic plasma.
Topics: Amidines; Guanidine; Guanidines; Humans; Plasma; Uremia | 1960 |
Blood levels of urea nitrogen, phenol, guanidine and creatinine in uremia.
Topics: Blood; Creatinine; Guanidine; Guanidines; Humans; Nitrogen; Phenol; Phenols; Urea; Uremia | 1951 |
Effect of NaCN on currents evoked by uremic retention solutes in dissociated mouse neurons.
Topics: Animals; Aspartic Acid; Cells, Cultured; Central Nervous System; Creatinine; Drug Interactions; Embr | 2004 |
[A study of guanidine metabolism in uremia, with special reference to serum guanidinoacetic acid in anephric patients].
Topics: Acute Kidney Injury; Adult; Aged; Animals; Blood Urea Nitrogen; Female; Glycine; Guanidine; Guanidin | 1984 |
Fast atom bombardment mass spectrometric determination of the molecular weight range of uremic compounds that displace phenytoin from protein binding: absence of midmolecular uremic toxins.
Topics: Drug Interactions; Guanidine; Guanidines; Hippurates; Humans; In Vitro Techniques; Indican; Methylgu | 1994 |
Effect of some products of protein catabolism on the endothelium-dependent and -independent relaxation of rabbit thoracic aorta rings.
Topics: Animals; Aorta, Thoracic; Creatinine; Endothelium, Vascular; Guanidine; Guanidines; In Vitro Techniq | 1993 |
Glutathione metabolism in uremic rat.
Topics: Animals; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Guanid | 1997 |
Guanidino compounds that are increased in cerebrospinal fluid and brain of uremic patients inhibit GABA and glycine responses on mouse neurons in cell culture.
Topics: Animals; Brain Chemistry; Cells, Cultured; Creatinine; Drug Synergism; GABA Antagonists; Glycine; Gu | 1990 |
Serum guanidino compound levels and clearances in uremic patients treated with continuous ambulatory peritoneal dialysis.
Topics: Adult; Aged; Dialysis Solutions; Female; Guanidine; Guanidines; Humans; Kidney Failure, Chronic; Mal | 1990 |
Determination of guanidino compounds by anion-exchange chromatography and amperometric detection.
Topics: Adult; Aged; Chromatography, Ion Exchange; Electrochemistry; Electrodes; Female; Guanidine; Guanidin | 1990 |
Guanidino compounds in uraemic dialysed patients.
Topics: Adult; Aged; Arginine; Creatine; Creatinine; Female; Guanidine; Guanidines; Humans; Male; Methylguan | 1986 |