guanidine has been researched along with Trypanosomiasis, African in 2 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (50.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Reid, CM | 1 |
Ebikeme, C | 1 |
Barrett, MP | 1 |
Patzewitz, EM | 1 |
Müller, S | 1 |
Robins, DJ | 1 |
Sutherland, A | 1 |
HAWKING, F | 1 |
2 other studies available for guanidine and Trypanosomiasis, African
Article | Year |
---|---|
Synthesis of novel benzamidine- and guanidine-derived polyazamacrocycles: Selective anti-protozoal activity for human African trypanosomiasis.
Topics: Amino Acid Motifs; Animals; Antiprotozoal Agents; Benzamidines; Biological Transport; Cell Line; Che | 2008 |
Trypanocidal action of p-biguanidoacetophenone amidinohydrazone.
Topics: Acetophenones; Animals; Guanidine; Guanidines; Mice; Pentamidine; Trypanocidal Agents; Trypanosoma b | 1962 |