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guanidine and Trypanosomiasis, African

guanidine has been researched along with Trypanosomiasis, African in 2 studies

Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.

Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reid, CM1
Ebikeme, C1
Barrett, MP1
Patzewitz, EM1
Müller, S1
Robins, DJ1
Sutherland, A1
HAWKING, F1

Other Studies

2 other studies available for guanidine and Trypanosomiasis, African

ArticleYear
Synthesis of novel benzamidine- and guanidine-derived polyazamacrocycles: Selective anti-protozoal activity for human African trypanosomiasis.
    Bioorganic & medicinal chemistry letters, 2008, Oct-15, Volume: 18, Issue:20

    Topics: Amino Acid Motifs; Animals; Antiprotozoal Agents; Benzamidines; Biological Transport; Cell Line; Che

2008
Trypanocidal action of p-biguanidoacetophenone amidinohydrazone.
    British journal of pharmacology and chemotherapy, 1962, Volume: 19

    Topics: Acetophenones; Animals; Guanidine; Guanidines; Mice; Pentamidine; Trypanocidal Agents; Trypanosoma b

1962