Page last updated: 2024-10-28

guanidine and Rida

guanidine has been researched along with Rida in 7 studies

Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.

Research Excerpts

ExcerptRelevanceReference
"Neurodegenerative human CJD and sheep scrapie are diseases caused by several different transmissible encephalopathy (TSE) agents."1.42Rapid chemical decontamination of infectious CJD and scrapie particles parallels treatments known to disrupt microbes and biofilms. ( Botsios, S; Manuelidis, L; Tittman, S, 2015)
"The variant susceptible to classical scrapie has a larger population of the intermediate state than the resistant variant."1.37Microsecond unfolding kinetics of sheep prion protein reveals an intermediate that correlates with susceptibility to classical scrapie. ( Chen, KC; Roder, H; Wedemeyer, WJ; Xu, M, 2011)
"These data demonstrate that loss of scrapie infectivity can be a reversible process and that copper can enhance this restoration of proteinase K resistance and infectivity."1.30Reversibility of scrapie inactivation is enhanced by copper. ( Aiken, J; Bartz, J; Marsh, R; McKenzie, D; Mirwald, J; Olander, D, 1998)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Botsios, S1
Tittman, S1
Manuelidis, L1
Chen, KC1
Xu, M1
Wedemeyer, WJ1
Roder, H1
Kocisko, DA1
Lansbury, PT1
Caughey, B2
McKenzie, D1
Bartz, J1
Mirwald, J1
Olander, D1
Marsh, R1
Aiken, J1
Peretz, D1
Scott, MR1
Groth, D1
Williamson, RA1
Burton, DR1
Cohen, FE1
Prusiner, SB1
Lahiff, S1
Glennon, M1
O'Brien, L1
Lyng, J1
Smith, T1
Maher, M1
Shilton, N1
Callahan, MA1
Xiong , L1

Other Studies

7 other studies available for guanidine and Rida

ArticleYear
Rapid chemical decontamination of infectious CJD and scrapie particles parallels treatments known to disrupt microbes and biofilms.
    Virulence, 2015, Volume: 6, Issue:8

    Topics: Amyloid; Animals; Biofilms; Cell Line; Creutzfeldt-Jakob Syndrome; Decontamination; Detergents; Guan

2015
Microsecond unfolding kinetics of sheep prion protein reveals an intermediate that correlates with susceptibility to classical scrapie.
    Biophysical journal, 2011, Sep-07, Volume: 101, Issue:5

    Topics: Animals; Disease Susceptibility; Guanidine; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Bi

2011
Partial unfolding and refolding of scrapie-associated prion protein: evidence for a critical 16-kDa C-terminal domain.
    Biochemistry, 1996, Oct-15, Volume: 35, Issue:41

    Topics: Animals; Cricetinae; Endopeptidase K; Guanidine; Guanidines; In Vitro Techniques; Mesocricetus; Mole

1996
Reversibility of scrapie inactivation is enhanced by copper.
    The Journal of biological chemistry, 1998, Oct-02, Volume: 273, Issue:40

    Topics: Animals; Brain; Copper; Cricetinae; Endopeptidase K; Guanidine; Mesocricetus; Prion Diseases; Protei

1998
Strain-specified relative conformational stability of the scrapie prion protein.
    Protein science : a publication of the Protein Society, 2001, Volume: 10, Issue:4

    Topics: Animals; Antibodies; Cricetinae; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Guanidine; Mesoc

2001
Species-specific PCR for the identification of ovine, porcine and chicken species in meta and bone meal (MBM).
    Molecular and cellular probes, 2001, Volume: 15, Issue:1

    Topics: Animal Feed; Animals; Biotechnology; Chickens; DNA; Endonucleases; Food Analysis; Guanidine; Meat; M

2001
Reversibility of scrapie-associated prion protein aggregation.
    The Journal of biological chemistry, 2001, Jul-27, Volume: 276, Issue:30

    Topics: Animals; Blotting, Western; Brain; Cell-Free System; Circular Dichroism; Cricetinae; Endopeptidase K

2001