guanidine has been researched along with Renal Insufficiency in 3 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A model of renal failure has been developed in male C57BL x Swiss-Webster mice using nephrectomy (NX) and/or arterial ligation." | 1.30 | Biochemical and histopathological changes in nephrectomized mice. ( Al Banchaabouchi, M; D'Hooge, R; De Deyn, PP; Levillain, O; Marescau, B; Van Daele, A; Van Marck, E, 1998) |
| "The four lenses from the renal failure patients were searched for evidence of carbamylation at lysyl or cysteinyl residues: carbamylation was not detected." | 1.29 | Glutathione adducts, not carbamylated lysines, are the major modification of lens alpha-crystallins from renal failure patients. ( Miesbauer, LR; Schwedler, J; Shun-Shin, GA; Smith, DL; Smith, JB; Sun, Y; Yang, Z; Zhou, X, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, JB | 1 |
| Shun-Shin, GA | 1 |
| Sun, Y | 1 |
| Miesbauer, LR | 1 |
| Yang, Z | 2 |
| Zhou, X | 1 |
| Schwedler, J | 1 |
| Smith, DL | 1 |
| Al Banchaabouchi, M | 2 |
| Marescau, B | 2 |
| D'Hooge, R | 2 |
| Van Marck, E | 1 |
| Van Daele, A | 1 |
| Levillain, O | 1 |
| De Deyn, PP | 2 |
3 other studies available for guanidine and Renal Insufficiency
| Article | Year |
|---|---|
Glutathione adducts, not carbamylated lysines, are the major modification of lens alpha-crystallins from renal failure patients.
Topics: Aged; Aged, 80 and over; Aging; Carbamates; Crystallins; Female; Glutathione; Guanidine; Guanidines; | 1995 |
Biochemical and histopathological changes in nephrectomized mice.
Topics: Animals; Arginine; Brain; Creatinine; Glycine; Guanidine; Guanidines; Ligation; Male; Mice; Mice, In | 1998 |
The effect of high protein diet on urea and guanidino compound levels in renal insufficient mice.
Topics: Animals; Body Weight; Chromatography, Gas; Dietary Proteins; Guanidine; Male; Mice; Mice, Inbred Str | 2001 |