guanidine has been researched along with Poliomyelitis in 32 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Poliomyelitis: An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Moreover, the use of inhibitors of poliovirus RNA synthesis helped to dissociate those two events more clearly." | 1.28 | Lack of direct correlation between p220 cleavage and the shut-off of host translation after poliovirus infection. ( Carrasco, L; Pérez, L, 1992) |
| "Guanidine-dependent polioviruses are obtained in vitro by subculturing Brunenders, Mahoney, and Sabin strains in the presence of increasing concentrations of guanidine." | 1.24 | POLIOVIRUS: GUANIDINE DEPENDENCE AND LOSS OF NEUROVIRULENCE FOR MONKEYS. ( BROTZU, G; FERRARI, W; GESSA, GL; LODDO, B; SPANEDDA, A, 1964) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (90.63) | 18.7374 |
| 1990's | 1 (3.13) | 18.2507 |
| 2000's | 1 (3.13) | 29.6817 |
| 2010's | 1 (3.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanner, EJ | 1 |
| Liu, HM | 1 |
| Oberste, MS | 1 |
| Pallansch, M | 1 |
| Collett, MS | 1 |
| Kirkegaard, K | 1 |
| CASCIO, D | 1 |
| Verheyden, B | 1 |
| Lauwers, S | 1 |
| Rombaut, B | 1 |
| CROWTHER, D | 1 |
| MELNICK, JL | 2 |
| RIGHTSEL, WA | 1 |
| DICE, JR | 1 |
| McALPINE, RJ | 1 |
| TIMM, EA | 1 |
| McLEAN, IW | 1 |
| DIXON, GJ | 1 |
| SCHABEL, FM | 1 |
| LODDO, B | 22 |
| BARRERA-ORO, JG | 1 |
| UEDA, T | 3 |
| TOYOSHIMA, S | 3 |
| TSUJI, T | 2 |
| SETO, Y | 3 |
| NOMOTO, J | 2 |
| MUNTONI, S | 2 |
| SPANEDDA, A | 6 |
| BROTZU, G | 6 |
| FERRARI, W | 8 |
| GARZIA, A | 1 |
| GESSA, GL | 1 |
| Pérez, L | 1 |
| Carrasco, L | 1 |
32 other studies available for guanidine and Poliomyelitis
| Article | Year |
|---|---|
Dominant drug targets suppress the emergence of antiviral resistance.
Topics: Animals; Antiviral Agents; Capsid; Drug Evaluation, Preclinical; Drug Resistance, Viral; Genome, Vir | 2014 |
The significance of methylguanidine in polio blood.
Topics: Guanidine; Guanidines; Poliomyelitis | 1948 |
Quantitative RT-PCR ELISA to determine the amount and ratio of positive- and negative strand viral RNA synthesis and the effect of guanidine in poliovirus infected cells.
Topics: Biotin; DNA Primers; Enzyme-Linked Immunosorbent Assay; Guanidine; HeLa Cells; Humans; Nucleic Acid | 2003 |
Studies of the inhibitory action of guanidine on poliovirus multiplication in cell cultures.
Topics: Amidines; Cell Culture Techniques; Cell Proliferation; Guanidine; Guanidines; Poliomyelitis; Poliovi | 1961 |
Antiviral effect of guanidine.
Topics: Animals; Antiviral Agents; Enterovirus; Guanidine; Guanidines; Haplorhini; Humans; Poliomyelitis; Po | 1961 |
[Inhibition of the in vitro multiplication of poliomyelitis viruses using guanidine].
Topics: Amidines; Guanidine; Guanidines; In Vitro Techniques; Poliomyelitis; Poliovirus | 1961 |
[On the inhibitory activity, in vitro, of guanidine against the poliomyelitis virus. II. Lack of action of derivatives and analogues of guanidine].
Topics: Amidines; Guanidine; Guanidines; In Vitro Techniques; Inorganic Chemicals; Organic Chemicals; Poliom | 1961 |
[On the inhibitory activity, in vitro, of guanidine against the poliomyelitis virus. III. Lack of antagonism of certain molecules against the inhibition of cytopathogenic effect produced by guanidine in comparisons on poliomyelitis virus I].
Topics: Amidines; Amino Acids; Antifibrinolytic Agents; Guanidine; Guanidines; Hostility; In Vitro Technique | 1961 |
[On the inhibitory activity, in vitro, of guanidine against the poliomyelitis virus. IV. Influence of guanidine on viral multiplication].
Topics: Amidines; Guanidine; Guanidines; In Vitro Techniques; Leadership; Poliomyelitis; Poliovirus | 1961 |
[On the inhibitory activity, in vitro, of guanidine against the poliomyelitis virus. V. Curative activity of guanidine in infections of cell cultures by poliomyelitis virus I].
Topics: Amidines; Cell Culture Techniques; Guanidine; Guanidines; In Vitro Techniques; Poliomyelitis; Poliov | 1961 |
[On the inhibitory activity, in vitro, of guanidine against the poliomyelitis virus. VI. Recent research on the possible mechanism of antipoliomyelitic action of guanidine in vitro].
Topics: Amidines; Guanidine; Guanidines; In Vitro Techniques; Poliomyelitis; Poliovirus; Research | 1961 |
The effect of guanidine: (1). On experimental poliomyelitis induced by oral administration of virus to cynomolgus monkeys; (2). On naturally occurring enteroviruses of cynomolgus monkeys.
Topics: Administration, Oral; Amidines; Animals; Enterovirus; Guanidine; Guanidines; Macaca fascicularis; Po | 1961 |
Antiviral effect of guanidine and its derivatives. I. The inhibitory effect of guanidine on the multiplication of poliomyelitis virus in tissue culture.
Topics: Amidines; Antiviral Agents; Guanidine; Guanidines; Immunologic Tests; Poliomyelitis; Poliovirus | 1961 |
[On the inhibitory activity, in vitro, of guanidine towards poliomyelitis virus. XIII. Guanidine-dependence induced in vitro in poliomyelitis virus].
Topics: Drug Resistance, Microbial; Enterovirus C, Human; Guanidine; Guanidines; In Vitro Techniques; Poliom | 1962 |
[On the inhibitory activity, in vitro, of guanidine towards poliomyelitis virus. XII. Characterization of the guanidine-resistance induced in vitro in the poliomyelitis virus].
Topics: Biochemical Phenomena; Drug Resistance, Microbial; Enterovirus C, Human; Guanidine; Guanidines; In V | 1962 |
Guanidine conditioned infectivity of ribonucleic acid extracted from a strain of guanidine-dependent polio-1-virus.
Topics: Communicable Diseases; Guanidine; Guanidines; Poliomyelitis; Poliovirus; RNA; RNA, Viral | 1963 |
[On the inhibitory action in vitro of guanidine on poliomyelitis virus. XIV. Infectivity of ribonucleic acid extracted from a strain of guanidine-resistant poliovirus 1].
Topics: Enterovirus C, Human; Guanidine; Guanidines; In Vitro Techniques; Poliomyelitis; Poliovirus; RNA; RN | 1963 |
Protection against poliovirus paralysis by pretreatment with a guanidine-dependent poliovirus strain.
Topics: Guanidine; Guanidines; Paralysis; Poliomyelitis; Poliovirus | 1963 |
Inhibitory effect of guanidine on several viruses including polio and measles.
Topics: Adenoviridae; Encephalitis; Encephalitis Viruses; Encephalitis, Japanese; Guanidine; Guanidines; Mea | 1963 |
REGRESSION OF GUANIDINE-DEPENDENCE IN CLONED GUANIDINE-DEPENDENT POLIO VIRUSES.
Topics: Clone Cells; Drug Resistance; Drug Resistance, Microbial; Guanidine; Guanidines; Poliomyelitis; Poli | 1963 |
[PROTECTION OF CERCOPITHECUS AETHIOPS AGAINST VIRULENT POLIOVIRUS BY INOCULATION WITH GUANIDINE-DEPENDENT POLIOVIRUS].
Topics: Animals; Chlorocebus aethiops; Enterovirus C, Human; Guanidine; Guanidines; Haplorhini; Metabolism; | 1963 |
THE ANTIVIRAL EFFECT OF GUANIDINE AND ITS DERIVATIVES: III. THE DEVELOPMENT OF GUANIDINE RESISTANT AND GUANIDINE DEPENDENT POLIO VIRUS IN TISSUE CULTURE.
Topics: Antiviral Agents; Culture Media; Drug Resistance; Drug Resistance, Microbial; Enterovirus C, Human; | 1963 |
[INHIBITING ACTIVITY IN VITRO OF PYRIMIDINO-GUANIDINE DERIVATIVES ON POLIOMYELITIS VIRUS].
Topics: Antihypertensive Agents; Antiviral Agents; Enterovirus C, Human; Guanidine; Guanidines; In Vitro Tec | 1963 |
POLIOVIRUS: GUANIDINE DEPENDENCE AND LOSS OF NEUROVIRULENCE FOR MONKEYS.
Topics: Animals; Guanidine; Guanidines; Haplorhini; Immunologic Tests; Pharmacology; Poliomyelitis; Poliovir | 1964 |
In vitro inhibition of infectivity of polio viruses by guanidine.
Topics: Amidines; Guanidine; Guanidines; In Vitro Techniques; Poliomyelitis; Poliovirus | 1962 |
[Inhibition of the multiplication in vitro of poliomyelitis virus by the action of guanidine. X. Further research on the antipoliomyelitic activity in vitro of derivatives of guanidine in relation to their molecular structure].
Topics: Amidines; Guanidine; Guanidines; In Vitro Techniques; Molecular Structure; Poliomyelitis; Poliovirus | 1962 |
[Inhibition of the multiplication in vitro of poliomyelitis virus by the action of guanidine. XI. Lack of antagonism of 24-dinitrophenol and methylene blue against the antipoliomyelitic effect of guanidine].
Topics: Amidines; Dinitrophenols; Guanidine; Guanidines; Hostility; In Vitro Techniques; Methylene Blue; Nit | 1962 |
[Inhibition of the multiplication in vitro of poliomyelitis virus by the action of guanidine. XI. Potentiation of the anti-poliomyelitic effect of guanidine by 5-fluorouracil].
Topics: Amidines; Fluorouracil; Guanidine; Guanidines; In Vitro Techniques; Poliomyelitis; Poliovirus; Uraci | 1962 |
[Inhibition of the multiplication in vitro of poliomyelitis viruses by guanidine. VII. Absence of interference of vitamins, purine and pyrimidine bases in the inhibition by guanidine].
Topics: Amidines; Guanidine; Guanidines; In Vitro Techniques; Poliomyelitis; Poliovirus; Purines; Pyrimidine | 1962 |
[Preliminary research on the protective activity of guanidine in poliomyelitis infection in the mouse].
Topics: Amidines; Animals; Guanidine; Guanidines; Mice; Poliomyelitis; Research | 1961 |
[Inhibition of the multiplication in vitro of poliomyelitis viruses by guanidine. VIII. Elective inhibitory activity of guanidine on the PCE of enteroviruses].
Topics: Amidines; Elective Surgical Procedures; Enterovirus; Guanidine; Guanidines; In Vitro Techniques; Pol | 1962 |
Lack of direct correlation between p220 cleavage and the shut-off of host translation after poliovirus infection.
Topics: Antiviral Agents; Cold Temperature; Eukaryotic Initiation Factor-4F; Guanidine; Guanidines; HeLa Cel | 1992 |