guanidine has been researched along with Pancreatic Neoplasms in 1 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hou, Q | 1 |
| Jiang, W | 1 |
| Li, W | 1 |
| Huang, C | 1 |
| Yang, K | 1 |
| Chen, X | 1 |
| Huang, M | 1 |
| Shu, C | 1 |
| Luo, G | 1 |
| Sun, H | 1 |
| Chu, Q | 1 |
| Wu, X | 1 |
1 other study available for guanidine and Pancreatic Neoplasms
| Article | Year |
|---|---|
Identification of a Novel, Potent, and Orally Bioavailable Guanidine-Based SHP2 Allosteric Inhibitor from Virtual Screening and Rational Structural Optimization for the Treatment of KRAS Mutant Cancers.
Topics: Animals; Early Detection of Cancer; Enzyme Inhibitors; Guanidine; Humans; Mice; Pancreatic Neoplasms | 2023 |