guanidine has been researched along with Ovarian Neoplasms in 3 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carriers of germ line mutations in breast cancer susceptibility gene BRCA1 have an increased risk of developing breast and ovarian cancers; missense mutations have, however, been difficult to assess for disease association." | 1.36 | Toward classification of BRCA1 missense variants using a biophysical approach. ( Cook, R; Itzhaki, LS; Rowling, PJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vargas, JR | 1 |
| Stanzl, EG | 1 |
| Teng, NN | 1 |
| Wender, PA | 1 |
| Rowling, PJ | 1 |
| Cook, R | 1 |
| Itzhaki, LS | 1 |
| Modrzejewska, H | 1 |
| Brzezińska, E | 1 |
| Dramiński, M | 1 |
| Zgit-Wróblewska, A | 1 |
| Krzykowska, K | 1 |
| Rozpończyk, E | 1 |
| Greger, J | 1 |
1 review available for guanidine and Ovarian Neoplasms
| Article | Year |
|---|---|
Cell-penetrating, guanidinium-rich molecular transporters for overcoming efflux-mediated multidrug resistance.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line, T | 2014 |
2 other studies available for guanidine and Ovarian Neoplasms
| Article | Year |
|---|---|
Toward classification of BRCA1 missense variants using a biophysical approach.
Topics: Algorithms; Binding Sites; BRCA1 Protein; Breast Neoplasms; Escherichia coli; Female; Fluorescence P | 2010 |
A study of the influence of newly synthesized acyclonucleosides and 1,2,3,4-tetrahydroisoquinoline derivatives on deoxythymidine and deoxycytidine kinase activities in human neurofibrosarcoma and ovarian cancer.
Topics: Carbon Radioisotopes; Deoxycytidine Kinase; Female; Guanidine; Humans; Kinetics; Neurofibrosarcoma; | 2003 |