guanidine has been researched along with Osteoarthritis in 6 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nikolaeva, SS | 1 |
| Roshchina, AA | 1 |
| Zon Chkhol, K | 1 |
| Bykov, VA | 1 |
| Rebrova, GA | 1 |
| Koroleva, OA | 1 |
| Yakovleva, LV | 1 |
| Abramov, YV | 1 |
| Rebrov, LB | 1 |
| Manicourt, D | 1 |
| Howell, DS | 1 |
| Moskowitz, RW | 1 |
| Goldberg, V | 1 |
| Malemud, C | 1 |
| Pita, JC | 1 |
| Vasan, N | 1 |
| Zhao, M | 1 |
| Yoneda, M | 1 |
| Ohashi, Y | 1 |
| Kurono, S | 1 |
| Iwata, H | 1 |
| Ohnuki, Y | 1 |
| Kimata, K | 1 |
| Bayliss, MT | 1 |
| Howat, S | 1 |
| Davidson, C | 1 |
| Dudhia, J | 1 |
| Trujillo, PE | 1 |
| Mannik, M | 1 |
6 other studies available for guanidine and Osteoarthritis
| Article | Year |
|---|---|
Some biochemical characteristics and water exchange in human articular cartilage in osteoarthrosis.
Topics: Cartilage; Cartilage, Articular; Chromatography, Gel; Collagen; Femur; Guanidine; Humans; Hydrolases | 2002 |
Application of new techniques to separation of proteoglycan aggregates from normal and destabilized rabbit articular cartilages.
Topics: Animals; Cartilage, Articular; Disease Models, Animal; Guanidine; Guanidines; Macromolecular Substan | 1984 |
Proteoglycans in normal and severely osteoarthritic human cartilage.
Topics: Carbohydrates; Cartilage, Articular; Centrifugation, Density Gradient; Guanidine; Guanidines; Humans | 1980 |
Evidence for the covalent binding of SHAP, heavy chains of inter-alpha-trypsin inhibitor, to hyaluronan.
Topics: Alpha-Globulins; Amino Acid Sequence; Binding Sites; Cells, Cultured; Chromatography, Gel; Chromatog | 1995 |
The organization of aggrecan in human articular cartilage. Evidence for age-related changes in the rate of aggregation of newly synthesized molecules.
Topics: Age Factors; Aggrecans; Autoradiography; Cartilage, Articular; Chromatography, Gel; Electrophoresis, | 2000 |
IgG is bound by antigen-antibody bonds and some IgG and albumin are bound by intermolecular disulfide bonds to cartilage in rheumatoid arthritis and osteoarthritis.
Topics: Antigen-Antibody Reactions; Arthritis, Rheumatoid; Buffers; Cartilage, Articular; Disulfides; Dithio | 1992 |